메뉴 건너뛰기




Volumn 8, Issue 10, 2008, Pages 1425-1429

Endophenotypes in the genetic research of ADHD over the last decade: Have they lived up to their expectations?

Author keywords

[No Author keywords available]

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; CATECHOL METHYLTRANSFERASE; DOPAMINE 4 RECEPTOR; DOPAMINE 5 RECEPTOR; DOPAMINE BETA MONOOXYGENASE; DOPAMINE TRANSPORTER;

EID: 54249103534     PISSN: 14737175     EISSN: 17448360     Source Type: Journal    
DOI: 10.1586/14737175.8.10.1425     Document Type: Editorial
Times cited : (26)

References (33)
  • 2
    • 0036674495 scopus 로고    scopus 로고
    • Neuroscience of attention-deficit/ hyperactivity disorder: The search for endophenotypes
    • Castellanos FX, Tannock R. Neuroscience of attention-deficit/ hyperactivity disorder: the search for endophenotypes. Nat. Rev. Neurosci. 3, 617-628 (2002).
    • (2002) Nat. Rev. Neurosci , vol.3 , pp. 617-628
    • Castellanos, F.X.1    Tannock, R.2
  • 3
    • 0038823525 scopus 로고    scopus 로고
    • The endophenotype concept in psychiatry: Etymology and strategic intentions
    • Gottesman II, Gould TD. The endophenotype concept in psychiatry: etymology and strategic intentions. Am. J. Psychiatry 160, 636-645 (2003).
    • (2003) Am. J. Psychiatry , vol.160 , pp. 636-645
    • Gottesman, I.I.1    Gould, T.D.2
  • 4
    • 0030065627 scopus 로고    scopus 로고
    • Parents of children with attention-deficit/ hyperactivity disorder: Psychological and attentional impairment
    • Murphy KR, Barkley RA. Parents of children with attention-deficit/ hyperactivity disorder: psychological and attentional impairment. Am. J. Orthopsychiatry 66, 93-102 (1996).
    • (1996) Am. J. Orthopsychiatry , vol.66 , pp. 93-102
    • Murphy, K.R.1    Barkley, R.A.2
  • 5
    • 0036840690 scopus 로고    scopus 로고
    • Neurocognitive impairments in nonpsychotic parents of children with schizophrenia and attention-deficit/hyperactivity disorder
    • Asarnow RF, Nuechterlein KH, Subotnik KL et al. Neurocognitive impairments in nonpsychotic parents of children with schizophrenia and attention-deficit/hyperactivity disorder. Arch. Gen. Psychiatry 59, 1053-1060 (2002).
    • (2002) Arch. Gen. Psychiatry , vol.59 , pp. 1053-1060
    • Asarnow, R.F.1    Nuechterlein, K.H.2    Subotnik, K.L.3
  • 6
    • 0033867903 scopus 로고    scopus 로고
    • Neuropsychological functioning in nonreferred siblings of children with attention deficit hyperactivity disorder
    • Seidman LJ, Biederman J, Monuteaux M, Weber W, Faraone SV. Neuropsychological functioning in nonreferred siblings of children with attention deficit hyperactivity disorder. J. Abnorm. Psychol. 109, 252-265 (2002).
    • (2002) J. Abnorm. Psychol , vol.109 , pp. 252-265
    • Seidman, L.J.1    Biederman, J.2    Monuteaux, M.3    Weber, W.4    Faraone, S.V.5
  • 7
    • 35248837050 scopus 로고    scopus 로고
    • Testing for neuropsychological endophenotypes in siblings discordant for attention-deficit/hyperactivity disorder
    • Bidwell LC, Willcutt EG, DeFries JC, Pennington BF. Testing for neuropsychological endophenotypes in siblings discordant for attention-deficit/hyperactivity disorder. Biol. Psychiatry 62, 991-998 (2007).
    • (2007) Biol. Psychiatry , vol.62 , pp. 991-998
    • Bidwell, L.C.1    Willcutt, E.G.2    DeFries, J.C.3    Pennington, B.F.4
  • 8
    • 39549093548 scopus 로고    scopus 로고
    • Deficits in visuo-spatial working memory, inhibition and oculomotor control in boys with ADHD and their non-affected brothers
    • Rommelse NN, Van der Stigchel S, Witlox J et al. Deficits in visuo-spatial working memory, inhibition and oculomotor control in boys with ADHD and their non-affected brothers. J. Neural Transm. 115, 249-260 (2008).
    • (2008) J. Neural Transm , vol.115 , pp. 249-260
    • Rommelse, N.N.1    Van der Stigchel, S.2    Witlox, J.3
  • 9
    • 40049102368 scopus 로고    scopus 로고
    • Speed, variability, and timing of motor output in ADHD: Which measures are useful for endophenotypic research?
    • Rommelse NN, Altink ME, Oosterlaan J et al. Speed, variability, and timing of motor output in ADHD: which measures are useful for endophenotypic research? Behav. Genet. 38, 121-132 (2008).
    • (2008) Behav. Genet , vol.38 , pp. 121-132
    • Rommelse, N.N.1    Altink, M.E.2    Oosterlaan, J.3
  • 11
    • 7244231017 scopus 로고    scopus 로고
    • Evaluating the endophenotype model of ADHD neuropsychological deficit: Results for parents and siblings of children with ADHD combined and inattentive subtypes
    • Nigg JT, Blaskey LG, Stawicki JA, Sachek J. Evaluating the endophenotype model of ADHD neuropsychological deficit: results for parents and siblings of children with ADHD combined and inattentive subtypes. J. Abnorm. Psychol. 113, 614-625 (2004).
    • (2004) J. Abnorm. Psychol , vol.113 , pp. 614-625
    • Nigg, J.T.1    Blaskey, L.G.2    Stawicki, J.A.3    Sachek, J.4
  • 12
    • 36048957548 scopus 로고    scopus 로고
    • Reaction time performance in ADHD: Improvement under fast-incentive condition and familial effects
    • Andreou P, Neale BM, Chen W et al. Reaction time performance in ADHD: improvement under fast-incentive condition and familial effects. Psychol. Med. 37, 1703-1715 (2007).
    • (2007) Psychol. Med , vol.37 , pp. 1703-1715
    • Andreou, P.1    Neale, B.M.2    Chen, W.3
  • 13
    • 41049107236 scopus 로고    scopus 로고
    • Support for an independent familial segregation of executive and intelligence endophenotypes in ADHD families
    • DOI: 10.1186/1744-9081-4-4 , Epub ahead of print
    • Rommelse NN, Altink ME, Oosterlaan J, Buschgens CJ, Buitelaar J, Sergeant JA. Support for an independent familial segregation of executive and intelligence endophenotypes in ADHD families. Psychol. Med. DOI: 10.1186/1744-9081-4-4 (2008) (Epub ahead of print).
    • (2008) Psychol. Med
    • Rommelse, N.N.1    Altink, M.E.2    Oosterlaan, J.3    Buschgens, C.J.4    Buitelaar, J.5    Sergeant, J.A.6
  • 14
    • 0035171492 scopus 로고    scopus 로고
    • Deficient inhibition as a marker for familial ADHD
    • Crosbie J, Schachar R. Deficient inhibition as a marker for familial ADHD. Am. J. Psychiatry 158, 1884-1890 (2001).
    • (2001) Am. J. Psychiatry , vol.158 , pp. 1884-1890
    • Crosbie, J.1    Schachar, R.2
  • 15
    • 20044379261 scopus 로고    scopus 로고
    • Inhibition of motor responses in siblings concordant and discordant for attention deficit hyperactivity disorder
    • Schachar RJ, Crosbie J, Barr CL et al. Inhibition of motor responses in siblings concordant and discordant for attention deficit hyperactivity disorder. Am. J. Psychiatry 162, 1076-1082 (2005).
    • (2005) Am. J. Psychiatry , vol.162 , pp. 1076-1082
    • Schachar, R.J.1    Crosbie, J.2    Barr, C.L.3
  • 18
    • 33750482252 scopus 로고    scopus 로고
    • Activation in ventral prefrontal cortex is sensitive to genetic vulnerability for attention-deficit hyperactivity disorder
    • Durston S, Mulder M, Casey BJ, Ziermans T, van Engeland H. Activation in ventral prefrontal cortex is sensitive to genetic vulnerability for attention-deficit hyperactivity disorder. Biol. Psychiatry 60, 1062-1070 (2006).
    • (2006) Biol. Psychiatry , vol.60 , pp. 1062-1070
    • Durston, S.1    Mulder, M.2    Casey, B.J.3    Ziermans, T.4    van Engeland, H.5
  • 19
    • 37849021590 scopus 로고    scopus 로고
    • Preliminary report of familial clustering of EEG measures in ADHD
    • Loo SK, Smalley SL. Preliminary report of familial clustering of EEG measures in ADHD. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B, 107-109 (2008).
    • (2008) Am. J. Med. Genet. B Neuropsychiatr. Genet , vol.147 B , pp. 107-109
    • Loo, S.K.1    Smalley, S.L.2
  • 20
    • 50849109805 scopus 로고    scopus 로고
    • Action monitoring in boys with attention-deficit/hyperactivity disorder, their nonaffected siblings, and normal control subjects: Evidence for an endophenotype
    • Albrecht B, Brandeis D, Uebel H et al. Action monitoring in boys with attention-deficit/hyperactivity disorder, their nonaffected siblings, and normal control subjects: evidence for an endophenotype. Biol. Psychiatry 64(7), 615-625 (2008).
    • (2008) Biol. Psychiatry , vol.64 , Issue.7 , pp. 615-625
    • Albrecht, B.1    Brandeis, D.2    Uebel, H.3
  • 21
    • 2342435328 scopus 로고    scopus 로고
    • Magnetic resonance imaging of boys with attention-deficit/hyperactivity disorder and their unaffected siblings
    • Durston S, Hulshoff Pol HE, Schnack HG et al. Magnetic resonance imaging of boys with attention-deficit/hyperactivity disorder and their unaffected siblings. J. Am. Acad. Child Adolesc. Psychiatry. 43, 332-340 (2004).
    • (2004) J. Am. Acad. Child Adolesc. Psychiatry , vol.43 , pp. 332-340
    • Durston, S.1    Hulshoff Pol, H.E.2    Schnack, H.G.3
  • 22
    • 33947724401 scopus 로고    scopus 로고
    • A structural MRI study in monozygotic twins concordant or discordant for attention/hyperactivity problems: Evidence for genetic and environmental heterogeneity in the developing brain
    • Van 't Ent D, Lehn H, Derks EM et al. A structural MRI study in monozygotic twins concordant or discordant for attention/hyperactivity problems: evidence for genetic and environmental heterogeneity in the developing brain. Neuroimage 35, 1004-1020 (2007).
    • (2007) Neuroimage , vol.35 , pp. 1004-1020
    • Van 't Ent, D.1    Lehn, H.2    Derks, E.M.3
  • 23
    • 37849002182 scopus 로고    scopus 로고
    • Familial vulnerability to ADHD affects activity in the cerebellum in addition to the prefrontal systems
    • Mulder MJ, Baeyens D, Davidson MC et al. Familial vulnerability to ADHD affects activity in the cerebellum in addition to the prefrontal systems. J. Am. Acad. Child Adolesc. Psychiatry 47, 68-75 (2008).
    • (2008) J. Am. Acad. Child Adolesc. Psychiatry , vol.47 , pp. 68-75
    • Mulder, M.J.1    Baeyens, D.2    Davidson, M.C.3
  • 24
    • 57349168683 scopus 로고    scopus 로고
    • A review and analysis of the relationship between neuropsychological measures and DAT1 in ADHD
    • DOI: 10.1002/ajmg.b.30848 , Epub ahead of print
    • Rommelse NNJ, Altink ME, Arias-Vásquez A et al. A review and analysis of the relationship between neuropsychological measures and DAT1 in ADHD. Am. J. Med. Genet. B Neuropsychiatr. Genet. DOI: 10.1002/ajmg.b.30848 (2008) (Epub ahead of print).
    • (2008) Am. J. Med. Genet. B Neuropsychiatr. Genet
    • Rommelse, N.N.J.1    Altink, M.E.2    Arias-Vásquez, A.3
  • 25
    • 46349084451 scopus 로고    scopus 로고
    • Neuropsychological endophenotype approach to genome-wide linkage analysis identifies susceptibility loci for ADHD on 2q21.1 and 13q12.11
    • Rommelse NN, Arias-Vásquez A, Altink ME et al. Neuropsychological endophenotype approach to genome-wide linkage analysis identifies susceptibility loci for ADHD on 2q21.1 and 13q12.11. Am. J. Hum. Genet. 83, 99-105 (2008).
    • (2008) Am. J. Hum. Genet , vol.83 , pp. 99-105
    • Rommelse, N.N.1    Arias-Vásquez, A.2    Altink, M.E.3
  • 26
    • 33645779095 scopus 로고    scopus 로고
    • Endophenotypes successfully lead to gene identification: Results from the collaborative study on the genetics of alcoholism
    • Dick DM, Jones K, Saccone N et al. Endophenotypes successfully lead to gene identification: results from the collaborative study on the genetics of alcoholism. Behav. Genet. 36, 112-126 (2006).
    • (2006) Behav. Genet , vol.36 , pp. 112-126
    • Dick, D.M.1    Jones, K.2    Saccone, N.3
  • 27
    • 37849053744 scopus 로고    scopus 로고
    • Dopamine transporter genotype conveys familial risk of attention-deficit/hyperactivity disorder through striatal activation
    • Durston S, Fossella JA, Mulder MJ et al. Dopamine transporter genotype conveys familial risk of attention-deficit/hyperactivity disorder through striatal activation. J. Am. Acad. Child Adolesc. Psychiatry 47, 61-67 (2008).
    • (2008) J. Am. Acad. Child Adolesc. Psychiatry , vol.47 , pp. 61-67
    • Durston, S.1    Fossella, J.A.2    Mulder, M.J.3
  • 28
    • 34748918319 scopus 로고    scopus 로고
    • Walters JT, Owen MJ. Endophenotypes in psychiatric genetics. Mol. Psychiatry 12, 886-890 (2007).
    • Walters JT, Owen MJ. Endophenotypes in psychiatric genetics. Mol. Psychiatry 12, 886-890 (2007).
  • 29
    • 20444423267 scopus 로고    scopus 로고
    • Statistical approaches to complex phenotypes: Evaluating neuropsychological endophenotypes for attention-deficit/hyperactivity disorder
    • Waldman ID. Statistical approaches to complex phenotypes: evaluating neuropsychological endophenotypes for attention-deficit/hyperactivity disorder. Biol. Psychiatry 57, 1347-1356 (2005).
    • (2005) Biol. Psychiatry , vol.57 , pp. 1347-1356
    • Waldman, I.D.1
  • 30
    • 33747325407 scopus 로고    scopus 로고
    • The adrenergic receptor α-2A gene (ADRA2A) and neuropsychological executive functions as putative endophenotypes for childhood ADHD
    • Waldman ID, Nigg JT, Gizer IR, Park L, Rappley MD, Friderici K. The adrenergic receptor α-2A gene (ADRA2A) and neuropsychological executive functions as putative endophenotypes for childhood ADHD. Cogn. Affect. Behav. Neurosci. 6, 18-30 (2006).
    • (2006) Cogn. Affect. Behav. Neurosci , vol.6 , pp. 18-30
    • Waldman, I.D.1    Nigg, J.T.2    Gizer, I.R.3    Park, L.4    Rappley, M.D.5    Friderici, K.6
  • 31
    • 20444396885 scopus 로고    scopus 로고
    • Neuropsychologic theory and findings in attention-deficit/ hyperactivity disorder: The state of the field and salient challenges for the coming decade
    • Nigg JT. Neuropsychologic theory and findings in attention-deficit/ hyperactivity disorder: the state of the field and salient challenges for the coming decade. Biol. Psychiatry 57, 1424-1435 (2005).
    • (2005) Biol. Psychiatry , vol.57 , pp. 1424-1435
    • Nigg, J.T.1
  • 32
    • 33745801135 scopus 로고    scopus 로고
    • An examination of the behavioral and neuropsychological correlates of three ADHD candidate gene polymorphisms (DRD4 7+, DBD TaqI A2, and DAT1 40 bp VNTR) in hyperactive and normal children followed to adulthood
    • Barkley RA, Smith KM, Fischer M, Navia B. An examination of the behavioral and neuropsychological correlates of three ADHD candidate gene polymorphisms (DRD4 7+, DBD TaqI A2, and DAT1 40 bp VNTR) in hyperactive and normal children followed to adulthood. Am. J. Med. Genet. B Neuropsychiatr. Genet. 141B, 487-498 (2006).
    • (2006) Am. J. Med. Genet. B Neuropsychiatr. Genet , vol.141 B , pp. 487-498
    • Barkley, R.A.1    Smith, K.M.2    Fischer, M.3    Navia, B.4
  • 33
    • 50549087030 scopus 로고    scopus 로고
    • Intra-individual variability in ADHD, autism spectrum disorders and Tourette's syndrome
    • Geurts HM, Grasman RP, Verté S et al. Intra-individual variability in ADHD, autism spectrum disorders and Tourette's syndrome. Neuropsychologia 46(13), 3030-3041 (2008).
    • (2008) Neuropsychologia , vol.46 , Issue.13 , pp. 3030-3041
    • Geurts, H.M.1    Grasman, R.P.2    Verté, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.