Digital imaging, spectroscopy, and liquid crystals in a hand-held, non-invasive device to determine hemoglobin concentration

Journal of the Society for Information Display

Volumn 15, Issue 6, 2007, Pages 399-407

  Suner, Selim ^a,b,c   McMurdy, John ^c   Jay, Gregory ^b   Crawford, Gregory ^c  

^a RHODE ISLAND HOSPITAL   (United States)

^b BROWN UNIVERSITY   (United States)

^c BROWN UNIVERSITY   (United States)

Author keywords

Anemia; Digital imaging; Hemoglobin; Liquid crystal; Spectroscopy

Indexed keywords

ANEMIA; BLOOD TESTS; COLOR DECOMPOSITIONS; DIGITAL IMAGES; DIGITAL IMAGING; GOLD STANDARDS; HAND-HELD DEVICES; HEALTH CONCERNS; HEMOGLOBIN CONCENTRATIONS; MEASURING; PARASITIC DISEASES; SPECTROSCOPIC CHARACTERISTICS; UNITED STATES; WORK-FORCE;

BLOOD; BLOOD VESSELS; BUBBLES (IN FLUIDS); CONCENTRATION (PROCESS); CRYSTALLOGRAPHY; CRYSTALS; DEVELOPING COUNTRIES; DIGITAL ARITHMETIC; ELECTROMAGNETIC WAVES; LIGHT SOURCES; LIQUID CRYSTALS; POWDERS;

HEMOGLOBIN;

EID: 54149097325     PISSN: 10710922     EISSN: None     Source Type: Journal    
DOI: 10.1889/1.2749326     Document Type: Article

References (28)

1. E DeMaeyer and M Adiels-Yagman, "The prevalance of anemia in the world," World Health Statistics 38, 302-316 (1985).
2. WHO Technical Report Series 405, 5-37 (1968).
3. E M Lackritz, C C Campbell, T K Ruebush, A W Hightower, W Wakube, R W Steketee, and JBO Were, "Effect of blood-transfusion on survival among children in a Kenyan hospital," Lancet 340, 524-528 (1992).
4. D Llewellynjones, "Severe anaemia in pregnancy (as seen in Kuala Lumpur, Malaysia)," Aust New Zealand J Obstet Gynaecol 5, 191-197 (1965).
5. G Gardiner, V Edgerton, B Senewiratne, B R J, and Y Ohira, "Physical Work Capacity and Metabolic Sress in Subjects with Iron Deficiency Anemia," Amer J Clinical Nutrition 30 (1977).
6. R J Stoltzfus, A Edward-Raj, M L Dreyfuss, M Albonico, A Montresor, M D Thapa, K P West, H M Chwaya, L Savioli, and J Tielsch, "Clinical pallor is useful to detect severe anemia in populations where anemia is prevalent and severe," J Nutrition 129, 1675-1681 (1999).
7. H D Kalter, G Burnham, P R Kolstad, M Hossain, J A Schillinger, N Z Khan, S Saha, V de Wit, N Kenya-Mugisha, B Schwartz, and R E Black, "Evaluation of clinical signs to diagnose anaemia in Uganda and Bangladesh, in areas with and without malaria," Bull World Health, Organization 75, 103-111 (1997).
8. O L Hung, N S Kwon, A E Cole, G R Dacpano, T Wu, W K Chiang, and L R Goldfrank, "Evaluation of the physician's ability to recognize the presence or absence of anemia, fever, and jaundice," Academic Emergency Medicine 7, 146-156 (2000).
9. M Chowdhury, V Chongsuuvivatwong, A Geater, H Akhter, and T Winn, "Taking a medical history and using a colour scale during clinical examination of pallor improves detection of anemia," Tropical Medicine and International Health, 7, 133-139 (2002).
10. E O Ekunwe, "Predictive value of conjunctival pallor in the diagnosis of anaemia," West Afr J Med 16, 246-250 (1997).
11. T Getaneh, T Girma, T Belachew, and S Teklemariam, "The utility of pallor detecting anemia in under five years old children," Ethiopian Medical J 38, 77-84 (2000).
12. S P Luby, P N Kazembe, S C Redd, C Ziba, O C Nwanyanwu, A W Hightower, C Franco, L Chitsulo, and J J Wirima, "Using clinical signs to diagnose anemia in African children," Bull World Health Organization 73, 477-482 (1995).
13. A Montresor, M Albonico, N Khalfan, R J Stoltzfus, J M Tielsch, H M Chwaya, and L Savioli, "Field trial of a haemoglobin colour scale: an effective tool to detect anaemia in preschool children," Tropical Medicine & International Health 5, 129-133 (2000).
14. M Sari, S de Pee, E Martini, S Herman, Sugiatmi, M W Bloem, and R Yip, "Estimating the prevalence of anaemia: a comparison of three methods," Bull World Health Organization 79, 506-511 (2001).
15. T N Sheth, N K Choudhry, M Bowes, and A S Detsky, "The relation of conjunctival pallor to the presence of anemia," J General Internal Medicine 12, 102-106 (1997).
16. M G N Spinelli, J M P Souza, S B Souza, and E H Sesoko, "Reliability and validity of palmar and conjunctival pallor for anemia detection purposes," Revista de Sade Pblica 37, 404-408 (2003).
17. C Valeiras, A Calvo, A Roca, F Gude, and A Gonzalez Quintela, "Value of touch in the diagnosis of fever and of paleness in the diagnosis of anemia. Observational study in adults," An Med Interna 19, 120-125 (2002).
18. N R van den Broek, C Ntonya, E Mhango, and S A White, "Diagnosing anaemia in pregnancy in rural clinics: assessing the potential of the Haemoglobin Colour Scale," Bull World Health Organization 77, 15-21 (1999).
19. M W Weber, S D Kellingray, A Palmer, S Jaffar, E K Mulholland, and B M Greenwood, "Pallor as a clinical sign of severe anaemia in children: an investigation in the Gambia," Bull World Health Organization 75, 113-118 (1997).
20. S Suner, G Crawford, J McMurdy, and G Jay, "Noninvasive determination of Hemoglobin by Digital Photography of Palpebral Conjunctiva," J Emergency Medicine (accepted for publication) (2007).
21. D M Haaland and E V Thomas, "Partial least-squares methods for spectral analyses. 1. Relation to other quantitative calibration methods and the extraction of qualitative information," Analytical Chemistry 60, 1193-1202 (1988).
22. D M Haaland and E V Thomas, "Partial least-squares methods for spectral analyses. 2. Application to simulated and glass spectral data," Analytical Chemistry 60, 1202-1208 (1988).
23. J W McMurdy, G D Jay, S Suner, F M Traspalacios, and G P Crawford, "Diffuse reflectance spectra of the palpebral conjunctiva and its utility as a noninvasive indicator of total hemoglobin," J Biomedical Optics 11, 014019 (2006).
24. G Lammel, S Schweizer, and P Renaud, "Microspectrometer based on a tunable optical filter of porous silicon," Sensors and Actuators A-Physical 92, 52-59 (2001).
25. D H You, C J Yu, and S D Lee, "Reflective configuration of vertically aligned deformed-helix ferroelectric liquid crystal display," Ferroelectries 278, 805-812 (2002).
26. H R Kim, Y W Lee, S J Kim, D W Kim, C J Yu, B Lee, and S D Lee, "A rotatable waveplate using a vertically aligned deformed-helix ferroelectric liquid crystal," Ferroelectrics 312, 479-484 (2004).
27. D V Wick, T Martinez, M V Wood, J M Wilkes, M T Gruneisen, V A Berenberg, M V Vasil'ev, A P Onokhov, and L A Beresnev, "Deformedhelix ferroelectric liquid-crystal spatial light modulator that demonstrates high diffraction efficiency and 370-line pairs mm resolution," Applied Optics 38, 3798-3803 (1999).
28. J W McMurdy, G D Jay, and G P Crawford, "Monolithic microspectrometer using tunable ferroelectric liquid crystals," Appl Phys Lett 89, 081105 (2006).