Increased nuclear expression of growth hormone receptor in uterine cervical neoplasms of women under 40 years old

Tohoku Journal of Experimental Medicine

Volumn 216, Issue 2, 2008, Pages 165-172

  Dehari, Reiko ^a   Nakamura, Yoshiyasu ^a   Okamoto, Naoyuki ^a   Nakayama, Hiroki ^a  

^a KANAGAWA CANCER CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE RECEPTOR;

ADULT; AGED; ARTICLE; CANCER GROWTH; CELL MEMBRANE; CELL POPULATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SQUAMOUS EPITHELIUM; STROMA CELL; UTERINE CERVIX CARCINOMA;

ADULT; AGED; CELL NUCLEUS; EPITHELIUM; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; RECEPTORS, SOMATOTROPIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STROMAL CELLS; UTERINE CERVICAL NEOPLASMS;

EID: 54149085728     PISSN: 00408727     EISSN: 13493329     Source Type: Journal    
DOI: 10.1620/tjem.216.165     Document Type: Article

References (20)

1. Abe, Y., Ito, K., Okamura, C., Niikura, H., Terada, Y., Murakami, T., Takano, T., Ozawa, N., Nagai, H., Wada, Y., Uehara, S., Watanabe, T., Tanigawa, S., Wagatsuma, S., Yoshida, Y., Tgarashi, T., Suzuki, M., Nakagawa, K., Okamura, K. & Yaegashi, N. (2004) Cervical Cytologic Examination During Physical Checkup of Pregnant Women: Cervical Cancer Screening in Women Under the Age of Thirty. Tohoku J. Exp. Med., 204, 221-228.
2. Blumenfeld, Z., Barkey, R.J., Youdim, M.B.H., Brandes, J.M. & Amit, T. (1992) Growth Hormone (GH) - Binding Protein Regulation by Estrogen, Progesterone, and Gonadotropins in Human: The Effect of Ovulation Induction with Menopausal Gonadotropins, GH, and Gestation. J. Clin. Endocrinol. Metab., 75, 1242-1249.
3. Conway-Campbell, B.L, Wooh, J.W., Brooks, A.J., Gordon, D., Brown, R.J., Lichanska, A.M., Chin, H.S., Barton, C.L., Boyle, G.M. & Parsons, P.G. (2007) Nuclear targeting of the growth hormone receptor resulting in dysregulation of cell proliferation and tumorigenesis. Proc. Natl. Acad. Sci. USA, 104, 13331-13336.
4. Feton, J., Chevret, S., Asselain, B., de La Rochefordiere, A., Mathieu, G., Labib, A., Durand, J.C. & Salmon, R.J. (1990) Invasive cancer of the uterine cervix in young women: retrospective study of 236 cases. Bull. Cancer, 77, 109-116. (in French. Abstract)
5. Foerster, V. & Murtagh, J. (2007) Human Papillomavirus (HPV) vaccines: a Canadian update. Issues Emerg. Health Technol., 109, 1-8.
6. Garcia-Caballero, T., Mertani, H.M., Lambert, A., Gallego, R., Fraga, M., Pintos, E., Forteza, J., Chevallier, M., Lobie, P.E., Vonderhaar, B.K., Berias, A. & Morel, G. (2000) Increased expression of growth hormone and prolactine receptors in hepatocellular carcinomas. Endocrine, 12, 265-271.
7. Gebre-Medhin, M., Kindblom, L.G., Wennbo, H., Tornell, J. & Meis-Kinblom, J.M. (2001) Growth hormone receptor is expressed in human breast cancer. Am. J. Pathol., 158, 1217-1222.
8. Gerbaulet, A., Lartigau, E., Haie-Meder, C., Michel, G., Prade, M. & Lhomme, C. (1994) Cervical cancer in the young woman. Contracept. Fertil. Sex., 22, 405-409. (in French. Abstract)
9. Ho, K.K., O'Sullivan, A.J., Weissberger, A.J. & Kelly, J.J. (1996) Sex steroid regulation of growth hormone secretion and action. Horm. Res., 45, 67-73.
10. Hull, K.L. & Harvey, S. (2002) GH as a co-gonadotropin: the relevance of correlation changes in GH secretion and reproductive state. J. Endocrinol., 172, 1-19.
11. Jentys, W. & Rustowski, J. (1972) Uterine cervix cancer in young women. Ginekol. Pol., 43, 353-356. (in Polish. Abstract)
12. Lincoln, D.T., Temmin, L., al-Jarallah, M.A., Mathew, T.C. & Dashti, H. (1995) Primary Ki-1 lymphoma of the skin: expression of growth hormone receptors. Nutrition, 11, 627-631.
13. Maddux, H.R., Varia, M.A., Spann, C.O., Fowler, W.C. & Rosenman, J.G. (1990) Invasive carcinoma of the uterine cervix in women age 25 or less. Int. J. Radiat. Oncol. Biol. Phys., 19, 701-706.
14. Moscicki, A.B., Burt, V.G., Kanowitz, S., Darragh, T. & Shiboski, S. (1999) The Significance of Squamous Metaplasia in the Development of Low Grade Squamous Intraepithelial Lesions in Young Women. Cancer, 85, 1139-1144.
15. Stygar, D., Muravitskaya, N., Eriksson, B., Eriksson, H. & Sahlin, L. (2003) Effects of SERM (selective estrogen receptor modulator) treatment on growth and proliferation in the rat uterus. Reprod. Biol. Endocrinol., 1, 40.
16. Temmim, L., Kolle, S., Baker, H. & Sinowatz, F. (2000) Expression of growth hormone receptor in human liposarcomas and lipomas. Oncol. Rep., 7, 757-760.
17. Vecchia, C., Franceschi, S., Decarli, A., Fasoli, M., Gentile, A., Parazzini, F. & Regallo, M. (1986) Sexual Factors, Venereal Diseases, and the Risk of Intraepithelial and Invasive Cervical Neoplasia. Cancer, 58, 935-941.
18. Vespasiani, G.U., Perrone, G., Galati, G., D'Avola, D., Zardi, E.M., Rabitti, C., Bianchi, A., DeDominicis, E., Afeltra, A. & Picardi, A. (2006) Subcellular shift of the hepatic growth hormone receptor with progression of hepatitis C virus-related chronic liver disease. Histopathology, 48, 822-830.
19. Wang, Z., Prins, G.S., Coschigano, K.T., Kopchick, J.J., Green, J.E., Ray, V.H., Hedayat, S., Christov, K.T., Unteman, T.G. & Swanson, S.M. (2005) Disruption of growth hormone signaling retards early stage of prostate carcinogenesis in the C3(1)/antigen mouse. Endocrinology, 146, 5188-5196.
20. Wu, X., Liu, F., Yao, X., Li, W. & Chen, C. (2007) Growth hormone receptor expression is up-regulated during tumorigenesis of human colorectal cancer. J. Surg. Res., 143, 294-299.