Synthesis and pharmacological screening of derivatives of isoxazolo[4,5-d]pyrimidine

European Journal of Medicinal Chemistry

Volumn 43, Issue 11, 2008, Pages 2498-2504

  Wagner, Edwin ^a   Al Kadasi, Kamal ^a   Zimecki, Michał ^b   Sawka Dobrowolska, Wanda ^c  

^a WROCLAW MEDICAL UNIVERSITY   (Poland)

^b INSTITUTE OF IMMUNOLOGY AND EXPERIMENTAL THERAPY   (Poland)

^c UNIVERSITY OF WROC AW   (Poland)

Author keywords

Antitumor agents; Immunosuppressant; Isoxazole 4,5 d pyrimidines; Isoxazoles

Indexed keywords

3 (1,3,4 OXADIAZOL 2 YL) 5 METHYL 7 PHENYLISOXAZOLO[4,5 D]PYRIMIDINE; 5 (4 AMINO 5 BENZOYLISOXAZOL 3 YL)[1,3,4]OXADIAZOLE 2 CARBOXAMIDE; [4 AMINO 3 (1,3,4 OXADIAZOL 2 YL)ISOXAZOL 5 YL](PHENYL)METHANONE; IMMUNOSUPPRESSIVE AGENT; ISOXAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; DRUG SCREENING; DRUG SYNTHESIS; FEMALE; HUMORAL IMMUNITY; MALE; MOUSE; NONHUMAN; SHEEP; SPLEEN CELL;

ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG EVALUATION, PRECLINICAL; FEMALE; HUMANS; ISOXAZOLES; MALE; MICE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PYRIMIDINES; SPLEEN;

EID: 54049153928     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.01.035     Document Type: Article

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