Mechanism of hydrolysis of dicholine esters with long polymethylene chain by human butyrylcholinesterase

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1784, Issue 11, 2008, Pages 1818-1824

  Grigoryan, Hasmik ^a   Halebyan, Ghukas ^a   Lefebvre, Bertrand ^b   Brasme, Bernardin ^b   Masson, Patrick ^b  

^a CJSC Scientific Research Institute of Biotechnology   (Armenia)

^b CENTRE DE RECHERCHES   (France)

Author keywords

Butyrylcholinesterase; Dicholinesters of dicarboxylic acids; Kinetic mass spectrometry; Two step hydrolysis, Molecular modeling (docking)

Indexed keywords

ADIPIC ACID; ADIPYLDICHOLINE; CARBON; CHOLINE DERIVATIVE; CHOLINESTERASE; DICARBOXYLIC ACID; DICHOLINE ESTER; POLY(METHYL METHACRYLATE); SEBACOYLDICHOLINE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONFORMATION; ENZYME ANALYSIS; ENZYME BINDING; HUMAN; HYDROLYSIS; MASS SPECTROMETRY; MOLECULAR MODEL; PRIORITY JOURNAL;

AMINO ACID MOTIFS; BUTYRYLCHOLINESTERASE; CARBON; CATALYTIC DOMAIN; CHOLINE; ESTERS; HUMANS; HYDROLYSIS; KINETICS; MASS SPECTROMETRY; METHANE; MODELS, BIOLOGICAL; MODELS, MOLECULAR; PIPECOLIC ACIDS; PROTEIN BINDING; SERINE;

EID: 54049143783     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2008.08.005     Document Type: Article

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