Chain length dependence of the interactions of bisquaternary ligands with the Torpedo nicotinic acetylcholine receptor

Biochemical Pharmacology

Volumn 73, Issue 3, 2007, Pages 417-426

  Carter, Chris R J ^a   Cao, Liren ^a   Kawai, Hideki ^b   Smith, Peter A ^a   Dryden, William F ^a   Raftery, Michael A ^b   Dunn, Susan M J ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Bisquaternary agonists; Ligand gated ion channels; Suberyldicholine; Torpedo nicotinic acetylcholine receptor; Xenopus oocyte expression

Indexed keywords

ACETYLCHOLINE; ADIPYL BISCHOLINE; AZELYL BISCHOLINE; BISCHOLINE ESTER; BISQUATERNARY LIGAND; DICHOLINE SUBERATE; DODECANYL BISCHOLINE; GLUTARYL BISCHOLINE; LIGAND; MALONYL BISCHOLINE; NICOTINIC RECEPTOR; OXALYL BISCHOLINE; PIMELYL BISCHOLINE; SEBACYL BISCHOLINE; SUXAMETHONIUM;

ACETYLCHOLINE RELEASE; ARTICLE; BINDING AFFINITY; BINDING SITE; DISSOCIATION CONSTANT; DRUG CONFORMATION; DRUG POTENCY; DRUG RECEPTOR BINDING; EQUILIBRIUM CONSTANT; LIGAND BINDING; MEMBRANE VESICLE; NONHUMAN; PRIORITY JOURNAL; TORPEDO; VOLTAGE CLAMP;

ACETYLCHOLINE; ANIMALS; BINDING, COMPETITIVE; CHOLINE; LIGANDS; NICOTINIC AGONISTS; PROTEIN CONFORMATION; RECEPTORS, NICOTINIC; STRUCTURE-ACTIVITY RELATIONSHIP; THENOYLTRIFLUOROACETONE; TORPEDO;

EID: 33845652693     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2006.10.011     Document Type: Article

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