BMI influences prognosis following surgery and adjuvant chemotherapy for lymph node positive breast cancer

Breast Journal

Volumn 14, Issue 4, 2008, Pages 357-365

  Vitolins, Mara Z ^a,c   Kimmick, Gretchen G ^b   Douglas Case, L ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c WAKE FOREST UNIVERSITY HEALTH SCIENCES   (United States)

Author keywords

BMI; Breast cancer; Recurrence; Time to recurrence; Weight

Indexed keywords

CYCLOPHOSPHAMIDE; DOXORUBICIN; FLUOROURACIL; PREDNISONE; PROGESTERONE RECEPTOR; TAMOXIFEN; VINCRISTINE;

ADULT; AGED; ARTICLE; BODY MASS; BREAST CANCER; CANCER ADJUVANT THERAPY; CANCER RECURRENCE; CANCER SURGERY; CANCER SURVIVAL; CONTROLLED STUDY; DISEASE FREE SURVIVAL; FEMALE; FOLLOW UP; HUMAN; LYMPH NODE DISSECTION; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MASTECTOMY; OBESITY; PROGNOSIS; TREATMENT OUTCOME; ADJUVANT CHEMOTHERAPY; AGE; BREAST TUMOR; CLINICAL TRIAL; LYMPH NODE; METABOLISM; MIDDLE AGED; MORTALITY; MULTIVARIATE ANALYSIS; PATHOLOGY; PHASE 2 CLINICAL TRIAL; PROPORTIONAL HAZARDS MODEL; PROSPECTIVE STUDY; SURVIVAL; TUMOR RECURRENCE;

ADULT; AGE FACTORS; AGED; BODY MASS INDEX; BREAST NEOPLASMS; CHEMOTHERAPY, ADJUVANT; FEMALE; FOLLOW-UP STUDIES; HUMANS; LYMPH NODES; LYMPHATIC METASTASIS; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASM RECURRENCE, LOCAL; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; RECEPTORS, PROGESTERONE; SURVIVAL ANALYSIS;

EID: 54049136137     PISSN: 1075122X     EISSN: 15244741     Source Type: Journal    
DOI: 10.1111/j.1524-4741.2008.00598.x     Document Type: Article

References (32)

1. American Cancer Society. Cancer Facts & Figures. Atlanta: American Cancer Society, 2007.
2. Kaye SA, Folsom AR, Soler JT, Prineas RJ, Potter JD. Associations of body mass and fat distribution with sex hormone concentrations in postmenopausal women. Int J Epidemiol 1991;20:151-6.
3. Yu H, Rohan T. Role of the insulin-like growth factor family in cancer development and progression. J Natl Cancer Inst 2000;92:1472-89.
4. Hankinson SE, Willett WC, Manson JE, et al. Alcohol, height, and adiposity in relation to estrogen and prolactin levels in postmenopausal women. J Natl Cancer Inst 1995;87:1297-302.
5. Siiteri PK. Adipose tissue as a source of hormones. Am J Clin Nutr 1987;45:277-82.
6. Bernstein L, Ross RK. Endogenous hormones and breast cancer risk. Epidemiol Rev 1993;15:48-65.
7. Selby C. Sex hormone binding globulin: origin, function, and clinical significance. Ann Clin Biochem 1990;27:532-11.
8. Goodwin PJ, Boyd NF. Body size and breast cancer prognosis: a critical review of the evidence. Breast Cancer Res Treat 1990;16:205-14.
9. Ryu SY, Kim CB, Nam CM, et al. Is body mass index the prognostic factor in breast cancer? A meta-analysis. J Korean Med Sci 2001;16:610-4.
10. Chlebowski RT, Aiello E, McTiernan A. Weight loss in breast cancer patient management. J Clin Oncol 2002;20:1128-43.
11. Kimmick GG, Shelton BJ, Case LD, Cooper MR, Muss HB. Long-term follow-up of a phase II trial studying a weekly doxorubi-cin-based multiple drug adjuvant therapy for stage II node-positive carcinoma of the breast. Breast Cancer Res Treat 2002;72:233-43.
12. Cox DR. Regression models and life-tables (with discussion). J Royal Stat Soc B 1972;34:187-220.
13. National Heart, Lung and Blood Institute. Clinical Guidelines on the Identification, Evaluation, and Treatment of Over-weight and Obesity in Adults: The Evidence Report. NIH Publication Number 98-4083. Bethesda, MD: National Institutes of Health, 1998.
14. Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 1958;53:457-81.
15. Therneau TM, Grambsch PM, Fleming TR. Martingale based residuals for survival models. Biometrika 1990;77:147-60.
16. Therneau TM, Grambsch PM. Modeling Survival Data: Extending the Cox Model. New York: Springer-Verlag, 2000.
17. Dignam JJ, Wieand K, Johnson KA, Fisher B, Xu L, Mamo-unas EP. Obesity, tamoxifen use, and outcomes in women with estrogen receptor positive early stage breast cancer. J Natl Cancer Inst 2003;95:1467-76.
18. Suissa S, Pollak M, Spitzer WO, Margolese R. Body size and breast cancer prognosis: a statistical explanation of the discrepancies. Cancer Res 1989;49:3113-6.
19. den Tonkelaar I, de Waard F, Seidell JC, Fracheboud J. Obesity and subcutaneous fat patterning in relation to survival of postmenopausal breast cancer patients participating in the DOM project. Breast Cancer Res Treat 1995;34:129-37.
20. Maehle BO, Tretli S. Pre-morbid body mass index in breast cancer: reversed effect on survival in hormone receptor negative patients. Breast Cancer Res Treat 1996;41:123-30.
21. Donegan WL, Hartz AJ, Rimm AA. The association of body weight with recurrent cancer of the breast. Cancer 1978;41:1590-4.
22. Boyd NF, Campbell JE, Germanson T, Thomson DB, Sutherland DJ, Meakin JW. Body weight and prognosis in breast cancer. J Natl Cancer Inst 1981;67:785-9.
23. Newman SC, Lees AW, Jenkins HJ. The effect of body mass index and oestrogen receptor level on survival of breast cancer patients. Int J Epidemiol 1997;26:484-90.
24. Tartter PI, Papatestas AE, Ioannovich J, Mulvihill MN, Lesnick G, Aufses AH Jr. Cholesterol and obesity as prognostic factors I breast cancer. Cancer 1981;47:2222-7.
25. Kimura M. Obesity as prognostic factors in breast cancer. Diabetes Res Clin Pract 1990;10:S247-51.
26. Haybittle J, Houghton J, Baum M. Social class and weight as prognostic factors in early breast cancer. Br J Cancer 1997;75:729-33.
27. Lees AW, Jenkins HJ, May CL, Cherian G, Lam EW, Hanson J. Risk factors and 10-year breast cancer survival in northern Alberta. Breast Cancer Res Treat 1989;13:143-51.
28. Hebert JR, Hurley TG, Ma Y. The effect of dietary exposures on recurrence and mortality in early stage breast cancer. Breast Cancer Res Treat 1998;51:17-28.
29. Lethaby AE, Mason BH, Harvey VJ, Holdaway IM. Survival of women with node negative breast cancer in the Auckland region. N Z Med J 1996;109:330-3.
30. van der Wal BC, Butzelaar RM, van der Meij S, Boermeester MA. Axillary lymph node ratio and total number of removed lymph nodes: predictors of survival in stage I and II breast cancer. Eur J Surg Oncol 2002;28:481-9.
31. Jain M, Miller AB. Pre-morbid body size and the prognosis of women with breast cancer. Int J Cancer 1994;59:363-8.
32. Borugian MJ, Sheps SB, Kim-Sing C, et al. Waist-to-hip ratio and breast cancer mortality. Am J Epidemiol 2003;158:963-8.