Modelling pulmonary blood flow

Respiratory Physiology and Neurobiology

Volumn 163, Issue 1-3, 2008, Pages 150-157

  Tawhai, Merryn H ^a   Burrowes, Kelly S ^b  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Heterogeneity; Model; Pulmonary

Indexed keywords

ARTERY BLOOD FLOW; COMPUTER MODEL; FRACTAL ANALYSIS; FUNCTIONAL MORPHOLOGY; HYDROSTATIC PRESSURE; LUNG BLOOD FLOW; LUNG CIRCULATION; LUNG FUNCTION; LUNG MODEL; LUNG PERFUSION; LUNG PRESSURE; LUNG STRUCTURE; MICROCIRCULATION; PRESSURE GRADIENT; PRIORITY JOURNAL; PULMONARY ARTERY; REGIONAL PERFUSION; REVIEW; VEIN BLOOD FLOW;

ANIMALS; COMPUTER SIMULATION; HUMANS; LUNG; MODELS, BIOLOGICAL; PULMONARY CIRCULATION; REGIONAL BLOOD FLOW;

EID: 54049132185     PISSN: 15699048     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.resp.2008.02.016     Document Type: Review

References (49)

1. Anthonisen N.R., and Milic-Emili J. Distribution of pulmonary perfusion in erect man. J. Appl. Physiol. 21 (1966) 760-766
2. Beck K.C., and Rehder K. Differences in regional vascular conductances in isolated dog lungs. J. Appl. Physiol. 61 (1986) 530-538
3. Bryan A.C., Bentivolgio L.G., Beerel F., MacLeish H., Zidulka A., and Bates D.V. Factors affecting regional distribution of ventilation and perfusion in the lung. J. Appl. Physiol. 19 (1964) 395-402
4. Burrowes K., Tawhai M., and Hunter P.J. Modeling RBC and neutrophil distribution through an anatomically based pulmonary capillary network. Ann. Biomed. Eng. 32 (2004) 585-595
5. Burrowes, K. S., 2005. An anatomically-based mathematical model of the human pulmonary circulation. Ph.D. Thesis. Auckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand.
6. Burrowes K.S., Hunter P.J., and Tawhai M.H. Anatomically-based finite element models of the human pulmonary arterial and venous trees including supernumerary vessels. J. Appl. Physiol. 99 (2005) 731-738
7. Burrowes K.S., Hunter P.J., and Tawhai M.H. Evaluation of pulmonary arterial flow heterogeneity via an image-based computational model. Acad. Radiol. 12 (2005) 1464-1474
8. Burrowes K.S., and Tawhai M.H. Computational predictions of pulmonary blood flow gradients: Gravity versus structure. Respir. Physiol. Neuro. 154 (2006) 515-523
9. deMello D., and Reid L.M. Arteries and veins. In: Crystal R.G., and West J.B. (Eds). The Lung: Scientific Foundations (1991), Raven Press Ltd., New York
10. Dhadwal A., Wiggs B., Doerschuk C., and Kamm R. Effects of anatomic variability on blood flow and pressure gradients in the pulmonary circulation. J. Appl. Physiol. 83 (1997) 1711-1720
11. Elliot F.M., and Reid L. Some new facts about the pulmonary artery and its branching pattern. Clin. Radiol. (1965)
12. Fahraeus R. The suspension stability of blood. Physiol. Rev. 9 (1929) 241-274
13. Fahraeus R., and Lindqvist T. The viscosity of the blood in narrow capillary tubes. J. Appl. Physiol. 96 (1931) 562-568
14. Fung Y., and Sobin S. Theory of sheet flow in lung alveoli. J. Appl. Physiol. 26 (1969) 472-488
15. Fung Y.C. Dynamics of blood flow and pressure-flow relationship. In: Crystal R.G., and West J.B. (Eds). The Lung: Scientific Foundations (1991), Raven Press, New York 1121-1145
16. Glenny R.W. Highlighted topic: physiological imaging of the lung. J. Appl. Physiol. 102 (2007) 1-2
17. Glenny R.W., Bernard S., Robertson H.T., and Hlastala M.P. Gravity is an important but secondary determinant of regional pulmonary blood flow in upright primates. J. Appl. Physiol. 86 (1999) 623-632
18. Glenny R.W., Hughes J.M.B., and West J.B. Point: counterpoint gravity is/is not the major factor determining the distribution of blood flow in the human lung. J. Appl. Physiol. 104 (2008) 1531-1533
19. Glenny R.W., and Robertson H.T. Fractal modeling of pulmonary blood flow heterogeneity. J. Appl. Physiol. 70 (1991) 1024-1030
20. Hanger C.C., Presson Jr. R.G., Okada O., Janke S.J., Watkins J.J., Wagner Jr. W.W., and Capen R.L. Computer determination of perfusion patterns in pulmonary capillary networks. J. Appl. Physiol. 82 (1997) 1283-1289
21. Hlastala M.P., and Berger A.J. Physiology of Respiration (2001), Oxford University Press, USA
22. Hlastala M.P., and Glenny R.W. Vascular structure determines pulmonary blood flow distribution. News Physiol. Sci. 14 (1999) 182-186
23. Hogg J.C. Neurophil kinetics in the pulmonary circulation. In: Said S.I. (Ed). The Pulmonary Circulation and Acute Lung Injury (1991), Futura, New York 253-269
24. Hogg J.C., and Doerschuk C.M. Leukocyte traffic in the lung. Annu. Rev. Physiol. 57 (1995) 97-114
25. Horsfield K. Morphometry of the small pulmonary arteries in man. Circ. Res. 42 (1978) 537-593
26. Horsfield K., Dart G., Olson D.E., Filley G.F., and Cumming G. Models of the human bronchial tree. J. Appl. Physiol. 31 (1971) 207-217
27. Horsfield K., and Gordon W.I. Morphometry of pulmonary veins in man. Lung 159 (1981) 211-218
28. Horsfield K., and Woldenberg M.J. Diameters and cross-sectional areas of branches in the human pulmonary arterial tree. Anat. Rec. 223 (1989) 245-251
29. Huang Y., Doerschuk C.M., and Kamm R.D. Computational modeling of RBC and neutrophil transit through the pulmonary capillaries. J. Appl. Physiol. 90 (2001) 545-564
30. Hughes J.M.B., Glazier J.B., Maloney J.E., and West J.B. Effect of extra-alveolar vessels on distribution of blood flow in the dog lung. J. Appl. Physiol. 25 (1968) 701-712
31. Jones A.T., Hansell D.M., and Evans J.H. Pulmonary perfusion in supine and prone postures: an electron beam study. J. Appl. Physiol. 76 (2001) 882-892
32. Krenz G., Linehan J., and Dawson C. A fractal continuum model of the pulmonary arterial tree. J. Appl. Physiol. 72 (1992) 2225-2237
33. Musch G., Layfield J.D.H., Harris R.S., Melo M.F.V., Winkler T., Callahan R.J., Fischman A.J., and Venegas J.G. Topographical distribution of pulmonary perfusion and ventilation, assessed by pet in supine and prone humans. J. Appl. Physiol. 93 (2002) 1841-1851
34. Ochs M., Nyengaard J.R., Jung A., Knudsen L., Voigt M., Wahlers T., Richter J., and Gundersen H.J. The number of alveoli in the human lung. Am. J. Resp. Crit. Care Med. 169 (2004) 120-124
35. Onuki T., and Nitta S. Computer simulation of geometry and hemodynamics of canine pulmonary arteries. Ann. Biomed. Eng. 21 (1993) 107-115
36. Parker J.C., Cave C.B., Ardell J.L., Hamm C.R., and Williams S.G. Vascular tree structure affects lung blood flow heterogeneity simulated in three dimensions. J. Appl. Physiol. 83 (1997) 1370-1382
37. Petersson J., Rohdin M., Sanchez-Crespo A., Nyren S., Jacobsson H., Larsson S.A., Lindahl S.G.E., Linnarsson D., Neradilek B., Polissar N.L., Glenny R.W., and Mure M. Posture primarily affects lung tissue distribution with minor effect on blood flow and ventilation. Respir. Physiol. Neuro. 156 (2007) 293-303
38. Pries A.R., Secomb T.W., and Gaehtgens P. Biophysical aspects of blood flow in the microvasculature. Cardiovasc. Res. 32 (1996) 654-667
39. Scultze-Neick I., Penny D.J., Derrick G.P.R.D., Rigby M.L., Kelleher A., Bush A., and Redington A.N. Pulmonary vascular-bronchial interactions: acute reduction in pulmonary blood flow alters lung mechanics. Heart 84 (2000) 284-289
40. Shaw A.M., Bunton D.C., Fisher A., McGrath J.C., Montgomery I., Daly C., and MacDonald A. V-shaped cushion at the origin of bovine pulmonary supernumerary arteries: Structure and putative function. J. Appl. Physiol. 87 (1999) 2348-2356
41. Spilker R.L., Feinstein J.A., Parker D.W., Reddy V.M., and Taylor C.A. Morphometry-based impedance boundary conditions for patient-specific modeling of blood flow in pulmonary arteries. Ann. Biomed. Eng. 35 (2007) 546-559
42. Tawhai M.H., Hunter P.J., Tschirren J., Reinhardt J.M., McLennan G., and Hoffman E.A. CT-based geometry analysis and finite element models of the human and ovine bronchial tree. J. Appl. Physiol. 97 (2004) 2310-2321
43. Wagner Jr. W.W., Todoran T.M., Tanabe N., Wagner T.M., Tanner J.A., Glenny R.W., and Presson Jr. R.G. Pulmonary capillary perfusion: intra-alveolar fractal patterns and interalveolar independence. J. Appl. Physiol. 86 (1999) 825-831
44. Weibel E.R. Morphometry of the Human Lung (1963), Springer-Verlag, Berlin
45. Weibel E.R. The Pathway For Oxygen: Structure and Function In Reply To: The Mammalian Respiratory System (1984), Harvard University Press, Cambridge, MA
46. West J.B. Respiratory Physiology-The Essentials (1979), Williams and Wilkins, Baltimore
47. West J.B. How it really happened-distribution of pulmonary blood flow. Am. J. Resp. Crit. Care. Med. 160 (1999) 1802-1803
48. West J.B., and Dollery C.T. Distribution of blood flow and ventilation-perfusion ratio in the lung, measured with radioactive carbon dioxide. J. Appl. Physiol. 15 (1960) 405-410
49. West J.B., Dollery C.T., and Naimark A. Distribution of blood flow in isolated lung; relation to vascular and alveolar pressures. J. Appl. Physiol. 19 (1964) 713-724