Computational modeling of RBC and neutrophil transit through the pulmonary capillaries

Journal of Applied Physiology

Volumn 90, Issue 2, 2001, Pages 545-564

  Huang, Yaqi ^a   Doerschuk, Claire M ^b   Kamm, Roger D ^a,c  

^a USA   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Hemodynamics; Microcirculation; Neutrophil margination; Pulmonary circulation; Simulation

Indexed keywords

ARTICLE; CAPILLARY FLOW; ERYTHROCYTE; HEMODYNAMICS; LUNG CAPILLARY PRESSURE; LUNG CIRCULATION; LUNG MODEL; NEUTROPHIL CHEMOTAXIS; PRIORITY JOURNAL;

EID: 0035140679     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.2001.90.2.545     Document Type: Article

References (41)

1. Effects of anatomic variability on blood flow and pressure gradients in the pulmonary capillaries
2. Comparison of neutrophil and capillary diameters and their relation to neutrophil sequestration in the lung
3. The site of neutrophil (PMN) accumulation within the pulmonary capillary bed after infusion of zymosan-activated plasma (ZAP)
4. Structural model for passive granulocyte behavior based on mechanical deformation and recovery after deformation tests
5. Passive material behavior of granulocytes based on large deformation and recovery after deformation tests
6. Apparent viscosity and cortical tension of blood granulocytes determined by micropipet aspiration
7. Analysis of the effects of measured white blood cell entrance times on hemodynamics in a computer model of a microvascular bed
8. Theory of sheet flow in lung alveoli
9. Stochastic flow in capillary blood vessels
10. Elasticity of pulmonary alveolar sheet
11. Pulmonary alveolar blood flow
12. Sites of leukocyte sequestration in the pulmonary microcirculation
13. Effect of capillary pressure and lung distension on capillary recruitment
14. Neutrophil kinetics and lung injury
15. Neutrophil kinetics in the pulmonary circulation
16. Erythrocyte and polymorphonuclear cell transit time and concentration in human pulmonary capillaries
17. Leukocyte traffic in the lung
18. A semi-empirical model of apparent blood viscosity as a function of vessel diameter and discharge hematocrit
19. Capillary network geometry and red cell distribution in hamster cremaster muscle
20. Flow through zone 1 lungs utilizes alveolar corner vessels
21. Effect of dispersion of vessel diameters and lengths in stochastic networks. II. Modeling of microvascular hematocrit distribution
22. Physiological neutrophil sequestration in the lung: Visual evidence for localization in capillaries
23. Three-dimensional reconstruction of alveoli in the rat lung for pressure-volume relations
24. Rapid flow of passive neutrophils into a 4 μm pipet and measurement of cytoplasmic viscosity
25. Temporal capillary perfusion patterns in single alveolar walls of intact dogs
26. Network models of peripheral circulation
27. Distribution of pulmonary capillary red blood cell transit times
28. Stability of alveolar capillary opening pressures
29. Blood flow in microvascular networks-experiments and simulation
30. Resistance to blood flow in microvessels in vivo
31. Size of microspheres passing through pulmonary circuit in the dog
32. Morphometry of human leukoctyes
33. Cell distribution in capillary networks
34. Mechanics of blood flow in microcirculation
35. Flow of red blood cells in narrow capillaries: Role of membrane tension
36. Pulmonary capillary length in dog, cat and rabbit
37. Morphometrische analyse von zahl, volumen, und oberflache der alveolen und kapillaren der menschlichen lunge
38. Contributions of capillary pathway size and neutrophil deformability to neutrophil transit through rabbit lungs
39. Cortical shell-liquid core model for passive flow of liquid-like spherical cells into micropipets