Adenosine and adenosine uptake inhibitors potentiate the neuromuscular blocking action of rocuronium mediated by adenosine A1 receptors in isolated rat diaphragms

Acta Anaesthesiologica Scandinavica

Volumn 52, Issue 10, 2008, Pages 1415-1422

  Narimatsu, E ^a   Niiya, T ^a   Kawamata, M ^a   Namiki, A ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 2 CHLORO 6 N CYCLOPENTYLADENOSINE; 6 N [2 (3,5 DIMETHOXYPHENYL) 2 (2 METHYLPHENYL)ETHYL]ADENOSINE; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE; ADENOSINE A1 RECEPTOR; DIPYRIDAMOLE; MIDAZOLAM; ROCURONIUM; THEOPHYLLINE;

ARTICLE; CONTROLLED STUDY; DIAPHRAGM; DRUG POTENTIATION; IC 50; IN VITRO STUDY; MALE; NEUROMUSCULAR BLOCKING; NONHUMAN; PRIORITY JOURNAL; RAT;

ADENOSINE; ANDROSTANOLS; ANIMALS; DIAPHRAGM; DIPYRIDAMOLE; DRUG SYNERGISM; ELECTRIC STIMULATION; MALE; MIDAZOLAM; MODELS, ANIMAL; NEUROMUSCULAR BLOCKING AGENTS; PHENETHYLAMINES; RATS; RATS, WISTAR; RECEPTOR, ADENOSINE A1; XANTHINES;

EID: 54049115884     PISSN: 00015172     EISSN: 13996576     Source Type: Journal    
DOI: 10.1111/j.1399-6576.2008.01714.x     Document Type: Article

References (25)

1. Amanullah AM, Bevegård S, Lindvall K, Aasa M. Assessment of left ventricular wall motion in angina pectoris by two-dimensional echocardiography and myocardial perfusion by technetium-99 m sestamibi tomography during adenosine-induced coronary vasodilation and comparison with coronary angiography. Am J Cardiol 1993 72 : 983 9.
2. Klabunde RE. Dipyridamole inhibition of adenosine metabolism in human blood. Eur J Pharmacol 1983 93 : 21 6.
3. Hammond JR, Paterson AR, Clanachan AS. Benzodiazepine inhibition of site-specific binding of nit robenzylthioinosine, an inhibitor of adenosine transport. Life Sci 1981 29 : 2207 14.
4. Bender AS, Hertz L. Similarities of adenosine uptake systems in astrocytes and neurons in primary cultures. Neurochem Res 1986 11 : 1507 24.
5. Smith DO. Sources of adenosine released during neuromuscular transmission in the rat. J Physiol 1991 432 : 343 54.
6. Todd KJ, Robitaille R. Purinergic modulation of synaptic signalling at the neuromuscular junction. Pflugers Arch 2006 452 : 608 14.
7. Correia-de-Sá P, Sebastião AM, Ribeiro JA. Inhibitory and excitatory effects of adenosine receptor agonists on evoked transmitter release from phrenic nerve ending of the rat. Br J Pharmacol 1991 103 : 1614 20.
8. Correia-de-Sá P, Timóteo MA, Ribeiro JA. Presynaptic A1 inhibitory/A2A facilitatory adenosine receptor activation balance depends on motor nerve stimulation paradigm at the rat hemidiaphragm. J Neurophysiol 1996 76 : 3910 9.
9. Silinsky EM. Adenosine decreases both presynaptic calcium currents and neurotransmitter release at the mouse neuromuscular junction. J Physiol 2004 558 : 389 401.
10. Schwartz AD, Whitacre CL, Lin Y, Wilson DF. Adenosine inhibits N-type calcium channels at the rat neuromuscular junction. Clin Exp Pharmacol Physiol 2003 30 : 174 7.
11. Oliveira L, Timoteo MA, Correia-de-Sa P. Modulation by adenosine of both muscarinic M1-facilitation and M2-inhibition of [3H]-acetylcholine release from the rat motor nerve terminals. Eur J Neurosci 2002 15 : 1728 36.
12. Sebastiao AM, Ribeiro JA. On the adenosine receptor and adenosine inactivation at the rat diaphragm neuromuscular junction. Br J Pharmacol 1988 94 : 109 20.
13. Oliveira L, Timoteo MA, Correia-de-Sa P. Tetanic depression is overcome by tonic adenosine A(2A) receptor facilitation of L-type Ca(2+) influx into rat motor nerve terminals. J Physiol 2004 560 : 157 68.
14. Nitahara K, Kornak P, Nagashima H, Vizi ES, Foldes FF, Dan K. Adenosine potentiation of neuromuscular blocking agents in guinea-pigs. Br J Anaesth 2000 84 : 245 7.
15. Nitahara K, Vizi ES, Shono S, Iihoshi M, Higuchi H, Higa K. Reversal of neuromuscular effects of adenosine by specific adenosine A1-receptor antagonist in live rats. Int J Neurosci 2005 115 : 405 10.
16. Prior C, Breadon EL, Lindsay KE. Modulation by presynaptic adenosine A1 receptors of nicotinic receptor antagonist-induced neuromuscular block in the mouse. Eur J Pharmacol 1997 327 : 103 8.
17. Paton WD, Waud DR. The margin of safety of neuromuscular transmission. J Physiol 1967 191 : 59 90.
18. Stepp DW, Van Bibber R, Kroll K, Feigl EO. Quantitative relation between interstitial adenosine concentration and coronary blood flow. Circ Res 1996 79 : 601 10.
19. Jonzon B, Karlberg KE, Querrol-Ferrer V, Sylvén C. Effects of adenosine on ex vivo filtragometry platelet aggregation in relation to plasma levels. Acta Physiol Scand 1997 159 : 245 8.
20. Uematsu T, Kozawa O, Matsuno H, Niwa M, Yoshikoshi H, Oh-uchi M, Kohno K, Nagashima S, Kanamaru M. Pharmacokinetics and tolerability of intravenous infusion of adenosine (SUNY4001) in healthy volunteers. Br J Clin Pharmacol 2000 50 : 177 81.
21. Narimatsu E, Aoki M. Involvement of the adenosine neuromodulatory system in the benzodiazepine-induced depression of excitatory synaptic transmissions in rat hippocampal neurons in vitro. Neurosci Res 1999 33 : 57 64.
22. Narimatsu E, Aoki M. Transient depression of excitatory synaptic transmission induced by adenosine uptake inhibition in rat hippocampal slices. Brain Res 2000 862 : 284 7.
23. Raschko JW, Synold TW, Chow W, Coluzzi P, Hamasaki V, Leong LA, Margolin KA, Morgan RJ, Shibata SI, Somlo G, Tetef ML, Yen Y, ter Veer A, Doroshow JH. A phase I study of carboplatin and etoposide administered in conjunction with dipyridamole, prochlorperazine and cyclosporine A. Cancer Chemother Pharmacol 2000 46 : 403 10.
24. Smith MT, Eadie MJ, Brophy TO. The pharmacokinetics of midazolam in man. Eur J Clin Pharmacol 1981 19 : 271 8.
25. Moschitto LJ, Greenblatt DJ. Concentration-independent plasma protein binding of benzodiazepines. J Pharm Pharmacol 1983 35 : 179 80.