Reversal of neuromuscular effects of adenosine by specific adenosine A1-receptor antagonist in live rats

International Journal of Neuroscience

Volumn 115, Issue 3, 2005, Pages 405-410

  Nitahara, Keiichi ^a,b   Vizi, E Sylvester ^a   Shono, Shinjiro ^a   Iihoshi, Mari ^a   Higuchi, Hideyuki ^a   Higa, Kazuo ^a  

^a FUKUOKA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

Adenosine; N(6) cyclopentyladenosine; Neuromuscular blocking agents; Purinergic P1; Receptors: adenosine A1; Vecuronium

Indexed keywords

6 N CYCLOPENTYLADENOSINE; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE; ADENOSINE A1 RECEPTOR AGONIST; ADENOSINE A1 RECEPTOR ANTAGONIST; DIPYRIDAMOLE; NEUROMUSCULAR BLOCKING AGENT; THEOPHYLLINE; VECURONIUM;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIAPHRAGM; DRUG EFFECT; DRUG POTENTIATION; MALE; NEUROMUSCULAR BLOCKING; NEUROMUSCULAR SYSTEM; NONHUMAN; PHRENIC NERVE; RAT; STEADY STATE; SYNAPTIC TRANSMISSION;

ADENOSINE; ANIMALS; DRUG INTERACTIONS; DRUG SYNERGISM; MALE; NEUROMUSCULAR JUNCTION; NEUROMUSCULAR NONDEPOLARIZING AGENTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ADENOSINE A1; SCIATIC NERVE; SYNAPTIC TRANSMISSION; VECURONIUM BROMIDE; XANTHINES;

EID: 14644408116     PISSN: 00207454     EISSN: None     Source Type: Journal    
DOI: 10.1080/00207450590520993     Document Type: Article

References (8)

1. Cunha, R. A., & Ribeiro, J. A. (2000). ATP as a presynaptic modulator. Life Science, 68, 119-137.
2. Giniatullin, R. A., & Scolova, E. M. (1998). ATP and adenosine inhibit transmitter release at the frog neuromuscular junction through distinct presynaptic receptors. British Journal of Pharmacology, 124, 839-844.
3. Gomes, J. A., Li, X., Pan, H. L., & Eisenach, J. C. (1999). Intrathecal adenosine interacts with a spinal noradrenergic system to produce antinociception in nerve-injured rats. Anesthesiology, 91, 1072-1079.
4. 1-purinoceptor-mediated inhibitory effect of adenosine and its stable analogues on the mouse hemidiaphragm preparation. Naunyn-Schmiedeberg's Archives of Pharmacology, 346, 197-202.
5. 1-receptor-mediated effect of adenosine on the release of acetylcholine from the myenteric plexus: Role and localization of ecto-ATPase and 5′-nucleotidase. Neuroscience, 67, 159-168.
6. Nitahara, K., Kornak, P., Nagashima, H., Vizi, E. S., Foldes, F. F., & Dan, K. (2000). Adenosine potentiation of neuromuscular blocking agents in guinea-pigs. British Journal of Anaesthesia, 84, 245-247.
7. Schwartz, A. D., Whitacre, C. L., Lin, Y., & Wilson, D. F. (2003). Adenosine inhibits N-type calcium channels at the rat neuromuscular junction Clinical Experimental Pharmacology and Physiology, 30, 174-177.
8. Sollevi, A., Ostergren, J., Fagrell, B., & Hjemdahl, P. (1984). Theophylline antagonizes cardiovascular responses to dipyridamole in man without affecting increases in plasma adenosine. Acta Physiologica Scandinavica, 121, 165-171.