Do cortisol concentrations predict short-term outcomes in extremely low birth weight infants?

Pediatrics

Volumn 122, Issue 4, 2008, Pages 775-781

  Aucott, Susan W ^a,e   Watterberg, Kristi L ^c   Shaffer, Michele L ^d   Donohue, Pamela K ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^d PENN STATE COLLEGE OF MEDICINE   (United States)

^e JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

Bronchopulmonary dysplasia; Extremely preterm infants; Hydrocortisone; Outcomes of high risk infants

Indexed keywords

HYDROCORTISONE; HYDROCORTISONE SODIUM SUCCINATE; HYPERTENSIVE AGENT; PLACEBO; ANTIINFLAMMATORY AGENT; DRUG DERIVATIVE;

ADRENAL INSUFFICIENCY; ARTICLE; BRAIN HEMORRHAGE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; DIAGNOSTIC VALUE; DIGESTIVE SYSTEM PERFORATION; DISEASE ASSOCIATION; ENCEPHALOMALACIA; EXTREMELY LOW BIRTH WEIGHT; FEMALE; HIGH RISK POPULATION; HUMAN; HYDROCORTISONE BLOOD LEVEL; INFANT; MAJOR CLINICAL STUDY; MALE; MORBIDITY; MORTALITY; MULTICENTER STUDY; OUTCOME ASSESSMENT; PREDICTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; RETROLENTAL FIBROPLASIA; RISK ASSESSMENT; TREATMENT DURATION; COMPARATIVE STUDY; DOSE RESPONSE; FOLLOW UP; NEWBORN; PROGNOSIS; SURVIVAL RATE; TIME; UNITED STATES;

ADRENAL INSUFFICIENCY; ANTI-INFLAMMATORY AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; FOLLOW-UP STUDIES; HUMANS; HYDROCORTISONE; INFANT, EXTREMELY LOW BIRTH WEIGHT; INFANT, NEWBORN; PROGNOSIS; PROSPECTIVE STUDIES; SURVIVAL RATE; TIME FACTORS; UNITED STATES;

EID: 54049104356     PISSN: 00314005     EISSN: 10984275     Source Type: Journal    
DOI: 10.1542/peds.2007-2252     Document Type: Article

References (28)

1. Watterberg KL, Demers LM, Scott SM, Murphy S. Chorioamnionitis and early lung inflammation in babies who develop bronchopulmonary dysplasia. Pediatrics. 1996;97(2):210-215
2. Watterberg KL, Scott SM, Naeye RL. Chorioamnionitis, Cortisol and acute lung disease in very low birth weight infants. Pediatrics. 1997;99(2). Available at: www.pediatrics.org/cgi/ content/full/99/2/e6
3. Scott SM, Watterberg KL. Effect of gestational age, postnatal age, and illness on plasma cortisol concentrations in premature infants. Pediatr Res. 1995;37(1):112-116
4. Huysman MW, Hokken-Koelega AC, De Ridder MA, Sauer PJ. Adrenal function in sick very preterm infants. Pediatr Res. 2000; 48(5):629-633
5. Watterberg KL, Gerdes JS, Cook KL. Impaired glucocorticoid synthesis in premature infants developing chronic lung disease. Pediatr Res. 2001;50(2):190-195
6. Scott SM, Cimino DF. Evidence for developmental hypopituitarism in ill preterm infants. J Perinatol. 2004;24(7):429-434
7. Watterberg KL, Scott SM. Evidence of early adrenal insufficiency in babies who develop bronchopulmonary dysplasia. Pediatrics. 1995;95(1):120-125
8. Watterberg KL, Gerdes JS, Gifford KL, Lin H-M. Prophylaxis against early adrenal insufficiency to prevent chronic lung disease in premature infants. Pediatrics. 1999;104(6): 1258 -1263
9. Watterberg KL, Gerdes JS, Cole CH, et al. Prophylaxis of early adrenal insufficiency to prevent bronchopulmonary dysplasia: a multicenter trial. Pediatrics. 2004;114(6):1649-1657
10. Peltoniemi O, Kari MA, Heinonen K, et al. Pretreatment cortisol values may predict responses to hydrocortisone administration for the prevention of bronchopulmonary dysplasia in high-risk infants. J Pediatr. 2005;146(5):632-637
11. Korte C, Styne D, Merritt TA, et al. Adrenocortical function in the very low birth weight infant: improved testing sensitivity and association with neonatal outcome. J Pediatr. 1996;128(2): 257-263
12. Lambert SWJ, Bruining HA, de Jong FH. Corticosteroid therapy in severe illness. N Engl J Med. 1997;337(18):1285-1292
13. Cooper MS, Stewart PM. Corticosteroid insufficiency in acutely illpatients. N Engl J Med. 2003;348(8):727-734
14. Joosten KFM, DeKleija ED, Westerterp M, et al. Endocrine and metabolic responses in children with meningococcal sepsis: striking differences between survivors and nonsurvivors. J Clin EndocrinolMetab. 2000;85(10):3746-3753
15. Seri I, Tan R, Evans J. Cardiovascular effects of hydrocortisone in preterm infants with pressor-resistant hypotension. Pediatrics. 2001;107(5):1070-1074
16. Ng PC, Lee CH, Lam CW, et al. Transient adrenocortical insufficiency of prematurity and systemic hypotension in very low birthweight infants. Arch Dis Child Fetal Neonatal Ed. 2004; 89(2):F119-F126
17. Ng PC, Lee CH, Bnur FL, et al. A double-blind, randomized, controlled study of a "stress dose" of hydrocortisone for rescue treatment of refractory hypotension in preterm infants. Pediatrics. 2006;117(2):367-375
18. Noori S, Friedlich P, Wong P, et al. Hemodynamic changes after low-dosage hydrocortisone administration in vasopressor-treated preterm and term infants. Pediatrics. 2006;118(4): 1456-1466
19. Anand KJS, Sipwell WG, Anysley-Green A. Randomised trial of fentanyl anesthesia in preterm babies undergoing surgery. Lancet. 1987;1(8524):62-66
20. Anand KJS, Hickey PR. Halothane-morphine compared with high-dose sufentanil for anesthesia and postoperative analgesia in neonatal cardiac surgery. N Engl J Med. 1992;326(1):1-9
21. Finer NN, Powers RJ, Ou CH, et al. Prospective evaluation of postnatal steroid administration: a 1-year experience from the California Perinatal Quality Care Collaborative. Pediatrics. 2006;117(3):704-712
22. Bolt RJ, van Weissenbruch MM, Popp-Snijders C, et al. Fetal growth and the function of the adrenal cortex in preterm infants. J Clin Endocrinol Metab. 2002;87(3):1194-1199
23. al Saedi S, Dean H, Dent W, Cronin C. Reference ranges for serum cortisol and 17-hydroxyprogesterone levels in preterm infants. J Pediatr. 1995;126(6):985-987
24. Banks BA, Stouffer N, Cnaan A, et al. Association of plasma cortisol and chronic lung disease in preterm infants. Pediatrics. 2001;107(3):494-498
25. Arnold JD, Bonacruz G, Garth LI, et al. Antenatal glucocorticoids modulate the amplitude of pulsatile cortisol secretion in premature neonates. Pediatr Res. 1998;44(6):876-881
26. Yoder B, Martin H. McCurnin DC, Coalson JJ. Impaired urinary cortisol excretion and early cardiopulmonary dysfunction in immature baboons. Pediatr Res. 2002;51(4):426-432
27. Heckmann M, Hartmann MF, Kampschulte B, et al. Cortisol production rates in preterm infants in relation to growth and illness: a noninvasive prospective study using gas chromatog- raphy-mass spectrometry. J Clin Endocrinol Metab. 2005;90(10): 5737-5742
28. 3) and hydrocortisone supplementation in preterm infants less than 30 weeks gestation: results of the THORN trial: Thyroid Hormone Replacement in Neonates. Pe- diatr R.es. 2003;53(1):48-56