Colletoic acid, a novel 11β-hydroxysteroid dehydrogenase type 1 inhibitor from Colletotrichum gloeosporioides SANK 21404

Journal of Antibiotics

Volumn 61, Issue 3, 2008, Pages 136-141

  Aoyagi, Azusa ^a   Ito Kobayashi, Mariko ^a   Ono, Yasunori ^a   Furukawa, Yoji ^a   Takahashi, Mizuki ^a   Muramatsu, Yasunori ^a   Umetani, Megumi ^a   Takatsu, Toshio ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

11 HSD1 inhibitor; Colletoic acid; Colletotrichum gloeosporioides; Fermentation; Isolation; Structure; Taxonomy

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 1; COLLETOIC ACID; COLLETOTRICHUM GLOEOSPORIORDES EXTRACT; PLANT EXTRACT; SESQUITERPENE; UNCLASSIFIED DRUG; 11BETA HYDROXYSTEROID DEHYDROGENASE; CYCLOPENTANE DERIVATIVE; ENZYME INHIBITOR; ESTER; SPIRO COMPOUND;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; COLLETOTRICHUM; COLLETOTRICHUM GLOEOSPORIORDES; DRUG ACTIVITY; DRUG ISOLATION; DRUG STRUCTURE; FUNGUS; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY DIFFRACTION; CHEMICAL STRUCTURE; CHEMISTRY; CLASSIFICATION; CONFORMATION; DOSE RESPONSE; DRUG ANTAGONISM; FERMENTATION; HUMAN; KINETICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

FUNGI; GLOMERELLA CINGULATA;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1; 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2; CHEMISTRY, PHYSICAL; COLLETOTRICHUM; CRYSTALLOGRAPHY, X-RAY; CYCLOPENTANES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; ESTERS; FERMENTATION; HUMANS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR CONFORMATION; SPIRO COMPOUNDS;

EID: 54049098360     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.1038/ja.2008.122     Document Type: Article

References (14)

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