Mucin immunohistochemistry in the diagnosis and mapping of extramammary Paget's disease

Journal of Cellular and Molecular Medicine

Volumn 12, Issue 5A, 2008, Pages 1605-1610

  Smith, R F ^a   Stern, B H ^b   Smith, A A ^a  

^a BARRY UNIVERSITY   (United States)

^b PA ^*  (United States)

Author keywords

Apomucin; Epithelial membrane antigen; Extramammary Paget's disease; MUC1; MUC5AC; Mucin; Mucin core protein; Paget cells

Indexed keywords

MUCIN;

ARTICLE; HUMAN; IMMUNOHISTOCHEMISTRY; METABOLISM; PAGET SKIN DISEASE;

HUMANS; IMMUNOHISTOCHEMISTRY; MUCINS; PAGET'S DISEASE, EXTRAMAMMARY;

EID: 54049096289     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2007.00188.x     Document Type: Article

References (42)

1. Lloyd J, Flanagan AM. Mammary and extramammary Paget's disease. J Clin Pathol. 2000 53 : 742 9.
2. Eller JJ, Eller WD. Tumors of the Skin. Philadelphia : Lea & Febiger 1951.
3. Jones RE, Austin C, Ackerman AB. Extramammary Paget's disease: a critical reexamination. Am J Dermatopathol. 1979 1 : 101 32.
4. Sasai Y, Nakama T, Kasuda M. Sialomucin in Paget cells of extrammary Paget's disease. Histochem J. 1983 15 : 987 97.
5. Kondo Y, Kashima K, Daa T, Fujiwara S, Nakayama I, Yokoyama Y. The ectopic expression of gastric mucin in extramam-mary and mammary Paget's disease. Am J Surg Pathol. 2002 26 : 617 23.
6. Toker C. Clear cells of the nipple epidermis. Cancer. 1970 25 : 601 10.
7. Helwig EB, Graham JH. Anogenital (extramammary) Paget's disease. A clinicopathological study. Cancer. 1963 16 : 387 403.
8. th ed. Philadelphia : Saunders 2000.
9. Reed W, Oppedal BR, Eeg Larsen T. Immunohistology is valuable in distinguishing between Paget's disease, Bowen's disease and superficial spreading malignant melanoma. Histopathology. 1990 16 : 583 8.
10. Marucci G, Betts CH, Golouh R, Peterse JL, Forschini MP, Eusebi V. Toker cells are probably precursors of Paget cell carcinoma: a morphological and ultrasound description. Virchows Arch. 2002 44 : 117 23.
11. Wilman JH, Golitz LE, Fitzpatrick JE. Vulvar clear cells of Toker: precursor of extramammary Paget's disease. Am J Dermatopathol. 2005 27 : 185 8.
12. Rosen T, Harting M, Gibson M. Treatment of Bowen's Disease with topical 5% imiquimod cream: retrospective study. Dermatol Surg. 2007 33 : 427 32.
13. Patel MJ, Stockfleth E. Does progression from actinic keratosis and Bowen's disease end with treatment: diclofenac 3% gel, an old drug in a new environment? Br J Dermatol. 2007 156 Suppl 3 : 53 6.
14. Pierie JP, Choudry U, Muzikansky A, Finkelstein DM, Ott MJ. Prognosis and management of extramammary Paget's disease and the association with secondary malignancies. J Am Coll Surg. 2003 196 : 45 50.
15. Thomas CJ, Wood GC, Marks VJ. Mohs micrographic surgery in the treatment of rare aggressive cutaneous tumors: the Geisinger experience. Dermatol Surg. 2007 13 : 333 9.
16. Yanagi T, Kato N, Osawa R. Radiotherapy for extramammary Paget's disease: histopathological findings after radiotherapy. Clin Dermatol. 2007 32 : 506 8.
17. Alguacil-Garcia A, O'Connor R. Mucin-negative biopsy in extra-mammary Paget's disease. A diagnostic problem. Histopathology. 1989 15 : 429 31.
18. Kohler S, Rouse RV, Smoller BR. The differential diagnosis of pagetoid cells in the epidermis. Mod Pathol. 1998 11 : 70 92.
19. Lundquist K, Kohler S, Rouse RV. Intraepidermal cytokeratin 7 expression is not restricted to Paget cells but is also seen in Toker cells and Merkel cells. Am J Surg Pathol. 1999 23 : 212 9.
20. Shah KD, Tabibzadeh SS, Gerber MA. Immunohistochemical distinction of Paget's disease from Bowen's disease and superficial spreading melanoma with the use of monoclonal cytokeratin antibodies. Am J Clin Pathol. 1987 88 : 689 95.
21. Willamson JD, Colome M I, Sahin A, Ayala AG, Medeiros J. Pagetoid Bowen's disease, a report of 2 cases that express cytokeratin 7. Arch Pathol Lab Med. 2000 124 : 427 30.
22. Yoshii N, Kitajima S, Yonezawa S, Matsukita S, Setoyama, Kanazaki T. Expression of mucin core proteins in extramammary Paget's disease. Pathol Int. 2002 52 : 360 89.
23. Liegl B, Gogg-Kamerer M, Tessaro E, Horn L-C, Moinfar F. Mammary and extra-mammary Paget's disease: an immunohistochemical study of 83 cases. Histopathology. 2007 50 : 439 47.
24. Litvinov SV, Hilkens J. The epithelial sialomucin, episialin, is sialylated during recycling. J Biol Chem. 1993 268 : 21364 71.
25. Moniaux N, Escande F, Porchet N, Aubert J-P, Batra SK. Structural organization and classification of the human mucin genes. Front Biosci. 2001 6 : D1192 206.
26. Schofield DP, Simms MS, Bishop MC. MUC1 mucin in urological malignancy. BJU Int. 2003 91 : 560 6.
27. Tatemoto Y, Saka M, Tanimura T, Mori M. Immunohistochemical observations on binding of monoclonal antibodies to epithelial membrane antigen in epithelial tumors of the oral cavity and skin. Oral Surg Oral Med Pathol. 1987 64 : 721 6.
28. Cooper HL, Cook IS, Theaker JM, Mallipeddi R, McGrath J, Friedmann, Healy E. Expression and glycosylation of MUC1 in epidermolysis bullosa-associated and sporadic cutaneous squamous cell carcinomas. Brit J Dermatol. 2004 151 : 540 5.
29. nd ed. New York, Blakiston, 1954.
30. McNulty JM, Kambour MJ, Smith AA. Use of an improved zirconyl hematoxylin stain in the diagnosis of Barrett's esophagus. J Cell Mol Med. 2004 8 : 382 7.
31. rd ed. Oxford, ButterworthHeinemann, 2000.
32. Davenport HA. Histological and histochemical technics. Philadelphia, Saunders, 1960.
33. Guyonnet-Duperat V, Audie J-P, Debailleul V, Laine A, Buisine M-P, Galiegue-Zoutina S, Pigny P, Degand P, Aubert J-P, Porchet N. Characterization of the human mucin gene MUC5AC: a consensus cysteine-rich domain for 11p15 mucin genes? Biochem J. 1995 305 : 211 9.
34. Gendler SJ, Spicer AP. Epithelial mucin genes. Ann Rev Physiol. 1995 57 : 607 34.
35. Reis CA, David L, Nielsen PA, Clausen H, Migorodskaya K, Roepstorff P, Sobrino-Simoes M. Immunohistochemical study of MUC5AC expression in human gastric carcinomas using a novel monoclonal anti-bocy. Int J Cancer. 1997 74 : 112 21.
36. Karanikas V, Patton K, Jamieson G, Pietersz G, McKenzie I. Affinity of anti-bodies to MUC1 antigens. Tumor Biol. 1997 19 : 71 8.
37. Pietersz GA, Li W, Osinski C, Apostolopoulos V, McKenzie IF. Definition of MHC-restricted CTL epitopes from non-variable number of tandem repeat sequences of MUC1. Vaccine 2000 18 : 2059 71.
38. Karsten U, Serttas N, Paulsen H, Danielczyk A, Goletz S. Binding patterns of DTR-specific antibodies reveal a glyco-sylation-conditioned tumor-specific epitope of the epithelial mucin (MUC1). Glycobiology 2004 14 : 681 92.
39. Appert DL, Otley CC, Phillips PK, Roenigk RK. Role of multiple scouting biopsies before Mohs micrographic surgery for extramammary Paget's disease. Dermatol Surg. 2005 31 : 1417 22.
40. Fanning J, Lambert L, Hale TM, Morris PC, Schuerch C. Paget's disease of the vulva: prevalence of associated vulvar adenocarcinoma, invasive Paget's disease, and recurrence after surgical excision. Am J Obstet Gynecol. 1999 180 : 24 7.
41. Hendi A, Brodland DG, Zitelli JA. Extramammary Paget's disease: surgical treatment with Mohs micrographic surgery. J Am Acad Dermatol. 2004 51 : 767 73.
42. Shepherd V, Davidson EJ, Davies-Humphreys J. Extramammary Paget's disease. Brit J Obset Gynecol. 2005 112 : 273 9.