Expression of mucin core proteins in extramammary Paget's disease

Pathology International

Volumn 52, Issue 5-6, 2002, Pages 390-399

  Yoshii, Noriko ^a   Kitajima, Shinichi ^b   Yonezawa, Suguru ^a   Matsukita, Sumika ^a   Setoyama, Mitsuru ^c   Kanzaki, Tamotsu ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b National Sanatorium Hoshizuka Keiaien   (Japan)

^c UNIVERSITY OF MIYAZAKI   (Japan)

Author keywords

Extramammary Paget's disease; Intraepithelial lesion; Invasive lesion; Microinvasive lesion; Mucin core protein

Indexed keywords

CORE PROTEIN; MUCIN 1; MUCIN 2; MUCIN 5AC; MUCIN 6; UNCLASSIFIED DRUG; CA 15-3 ANTIGEN; MUC 2 PROTEIN; MUCIN; TUMOR MARKER;

ADULT; AGED; APOCRINE GLAND; ARTICLE; CANCER INVASION; CELL INVASION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; PAGET SKIN DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SEBACEOUS GLAND; SKIN DEFECT; SKIN EPITHELIUM; SWEAT GLAND; BIOSYNTHESIS; FEMALE GENITAL TRACT TUMOR; MALE GENITAL TRACT TUMOR; METABOLISM; MIDDLE AGED; PATHOLOGY; PENIS; SCROTUM; SKIN; VULVA;

AGED; AGED, 80 AND OVER; CA-15-3 ANTIGEN; FEMALE; GENITAL NEOPLASMS, FEMALE; GENITAL NEOPLASMS, MALE; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGE; MUCINS; PAGET'S DISEASE, EXTRAMAMMARY; PENIS; SCROTUM; SKIN; SUPPORT, NON-U.S. GOV'T; TUMOR MARKERS, BIOLOGICAL; VULVA; HUMANS; MIDDLE AGED;

EID: 0036019566     PISSN: 13205463     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1827.2002.01364.x     Document Type: Article

References (49)

1. Mammary and extramammary Paget's disease
2. A comparative study of cytokeratin expression in Paget cells located at various sites
3. Gene expression of gastric type mucin (MUC5AC) in pancreatic tumors: Its relationship with the biological behavior of the tumor
4. Immunohistochemical study of MUC5AC expression in human gastric carcinomas using a novel monoclonal antibody
5. Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin
6. Cloning and sequencing of a human pancreatic tumor mucin cDNA
7. Episialin, a carcinoma-associated mucin, is generated by a polymorphic gene encoding splice variants with alternative amino termini
8. Molecular cloning of human intestinal mucin cDNAs. Sequence analysis and evidence for genetic polymorphism
9. Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5)
10. Characterization of the human mucin gene MUC5AC: A consensus cysteine-rich domain for 11p15 mucin genes?
11. Degenerate 87-base-pair tandem repeats create hydrophilic/hydrophobic alternating domains in human mucin peptides mapped to 11p15
12. Human gastric mucin. Identification of a unique species by expression cloning
13. Molecular cloning, sequence, and specificity of expression of the gene encoding the low molecular weight human salivary mucin (MUC7)
14. Chromosomal localization of a human mucin gene (MUC8) and cloning of the cDNA corresponding to the carboxy terminus
15. Allelic polymorphism and chromosomal localization of the human oviductin gene (MUC9)
16. Intestinal metaplasia of human stomach displays distinct patterns of mucin (MUC1, MUC2, MUC5AC, and MUC6) expression
17. Mucin core protein expression in extrahepatic bile duct carcinoma is associated with metastases to the liver and poor prognosis
18. Immunohistochemical study of mucin carbohydrates and core proteins in hepatolithiasis and cholangiocarcinoma
19. Immunohistochemical study of mucin carbohydrates and core protein in human pancreatic tumors
20. MUC1 mucin expression as a marker of progression and metastasis of human colorectal carcinoma
21. Expression of MUC1 and MUC2 mucin antigens in intrahepatic bile duct tumors: Its relationship with a new morphological classification of cholangiocarcinoma
22. MUC2 gene expression is found in noninvasive tumors but not in invasive tumors of the pancreas and liver: Its close relationship with prognosis of the patients
23. Tissue and tumor distribution of human polymorphic epithelial mucin
24. Mucin glycoproteins in gastrointestinal malignancies and metastasis
25. A core protein epitope of the polymorphic epithelial mucin detected by the monoclonal antibody SM-3 is selectively exposed in a range of primary carcinomas
26. Expression of mucin carbohydrates and core proteins in carcinomas of the ampulla of Vater: Their relationship to prognosis
27. Expression of MUC1 and MUC2 mucins in gastric carcinomas: Its relationship with the prognosis of the patients
28. Expression cloning of gastric mucin complementary DNA and localization of mucin gene expression
29. MUC6 apomucin shows a distinct normal tissue distribution that correlates with lewis antigen expression in the human stomach
30. Diversity of mucin genes, structure, function, and expression
31. Mucin genes and the proteins they encode: Structure, diversity, regulation
32. MUC-2 human small intestinal mucin gene structure: Repeated arrays and polymorphism
33. Molecular cloning of human intestinal mucin (MUC) cDNA. Identification of the amino terminus and overall sequence similarity to preprovon Willbrand factor
34. Vulvar Paget's disease: A clinicopathologic and immunohistochemical study of 19 cases
35. Comparative study for histology, proliferative activity, glycoproteins, and p53 protein between old and recent colorectal adenomas in Japan
36. Mammary and extramammary Paget's disease: Expression of Ca 15-3, Ka-93, CA 19-9 and CD44 in Paget cells and adjacent normal skin
37. DF3 (CA15-3) antibody as a marker of cutaneous adnexal tumors
38. Tumor and cysts of the epidermis
39. Mammary and extramammary Paget's disease
40. Cytokeratins, CEA, and mucin histochemistry in the diagnosis and characterization of extramammary Paget's disease
41. Stimulation of growth by both androgen and estrogen of the EMP-K1 transplantable tumor with androgen and estrogen receptors from human extramammary Paget's disease in nude mice
42. Expression of gastric type mucins in mammary Paget's disease
43. Expression of mucin antigens in human cancers and its relationship with malignancy potential
44. Effect of MUC1 mucin and anti-adhesion molecule on tumor cell growth
45. Suppression of cellular aggregation by high level of episialin
46. Episialin (MUC1) inhibits cytotoxic lymphocyte-target cell interaction
47. Episialin (MUC1) over-expression inhibits integrin-mediated cell adhesion to extracellular matrix components
48. Cancer-associated MUC1 mucin inhibits human T-cell proliferation, which is reversible by IL-2
49. A mechanism for inhibition of E-cadherin mediated cell-cell adhesion by the membrane-associated mucin episialin/MUC1