Contrast-Enhanced Transrectal Ultrasound for Assessing Vascularization of Hypoechoic BPH Nodules in the Transition and Peripheral Zones: Comparison with Pathological Examination

Ultrasound in Medicine and Biology

Volumn 34, Issue 11, 2008, Pages 1758-1764

  Yang, Jing Chun ^a   Tang, Jie ^a   Li, Yanmi ^a   Fei, Xiang ^a   Shi, Huaiyin ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Benign prostatic hyperplasia (BPH); Contrast agent; microvessel density (MVD); Ultrasound; vascular endothelial growth factor (VEGF)

Indexed keywords

BENIGN PROSTATIC HYPERPLASIA (BPH); CONTRAST AGENT; MICROVESSEL DENSITY (MVD); ULTRASOUND; VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF);

ABERRATIONS; ACOUSTIC WAVES; BIOACTIVITY; BIOPSY; BLOOD VESSELS; IMAGE SEGMENTATION; OPTICAL PROPERTIES; PEPTIDES; SELF ASSEMBLY; ULTRASONIC IMAGING; ULTRASONICS;

ENDOTHELIAL CELLS;

CD34 ANTIGEN; PROSTATE SPECIFIC ANTIGEN; SONOVUE; VASCULOTROPIN;

ADULT; AGED; ARTICLE; CAPILLARY DENSITY; CLINICAL ASSESSMENT; CONTRAST ENHANCEMENT; CONTROLLED STUDY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PERIPHERAL CIRCULATION; PRIORITY JOURNAL; PROSTATE BIOPSY; PROSTATE HYPERTROPHY; TRANSRECTAL ULTRASONOGRAPHY; VASCULARIZATION;

AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; BIOPSY; CONTRAST MEDIA; HUMANS; MALE; MIDDLE AGED; NEOVASCULARIZATION, PATHOLOGIC; PHOSPHOLIPIDS; PROSTATE; PROSTATIC HYPERPLASIA; SULFUR HEXAFLUORIDE; ULTRASONOGRAPHY, INTERVENTIONAL; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 54049093682     PISSN: 03015629     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ultrasmedbio.2008.04.009     Document Type: Article

References (22)

1. Egawa S., Ohori M., Uchida T., Mashimo S., and Kuwao S. Nodular hyperplasia in the peripheral zone of the prostate gland. Br J Urol 74 (1994) 520-521
2. Foster C.S. Pathology of benign prostatic hyperplasia. Prostate 9 Suppl (2000) 4
3. Jackson M.W., Bentel J.M., and Tilley W.D. Vascular endothelial growth factor (VEGF) expression in prostate cancer and benign prostatic hyperplasia. J Urol 157 (1997) 2323-2328
4. Halpern E.J., and Strup S.E. Using gray-scale and color and power Doppler sonography to detect prostatic cancer. AJR Am J Roentgenol 174 (2000) 623-627
5. Halpern E.J., McCue P.A., and Aksnes A.K. Contrast-enhanced US of the prostate with Sonazoid: comparison with whole-mount prostatectomy specimens in 12 patients. Radiology 222 (2002) 361-366
6. Hamper U.M., Sheth S., Walsh P.C., Holtz P.M., and Epstein J.I. Stage B adenocarcinoma of the prostate: Transrectal US and pathologic correlation of nonmalignant hypoechoic peripheral zone lesions. Radiology 180 (1991) 101-104
7. Keck P.J., Hauser S.D., Krivi G., Sanzo K., Warren T., Feder J., and Connolly D.T. Vascular permeability factor, an endothelial cell mitogen related to PDGF. Science 246 (1989) 1309-1312
8. Kerley S.W., Corica F.A., and Qian J. Peripheral zone involvement by prostatic hyperplasia. J Urol Pathol 6 (1997) 87-94
9. Leung D.W., Cachianes G., Kuang W.J., Goeddel D.V., and Ferrara N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246 (1989) 1306-1309
10. McNeal J.E. Normal and pathologic anatomy of prostate. Urology 17 Suppl (1981) 11
11. Moore R.A. Benign hypertrophy of the prostate: A morphological study. J Urol 50 (1993) 680-710
12. Ohori M., Egawa S., and Wheeler T.M. Nodules resembling nodular hyperplasia in the peripheral zone of the prostate gland. J Urol Pathol 2 (1994) 222-223
13. Oyen R.H., Van de Voorde W.M., Van Poppel H.P., Brys P.P., Ameye F.E., Franssens Y.M., Baert A.L., and Baert L.V. Benign hyperplastic nodules that originate in the peripheral zone of the prostate gland. Radiology 189 (1993) 707-711
14. Patel U., and Rickards D. The diagnostic value of color Doppler flow in the peripheral zone of the prostate, with histological correlation. Br J Urol 74 (1994) 590-595
15. Ramsey E.W. Benign prostatic hyperplasia: A review. Can J Urol 7 (2000) 1135
16. Ravindranath N., Wion D., Brachet P., and Djakiew D. Epidermal growth factor modulates the expression of vascular endothelial growth factor in the human prostate. J Androl 22 (2001) 432-443
17. Sun H.B., Xia S.J., and Tang X.D. Expression of different genes in transitional zone and peripheral zone of human normal prostate. Natl Med J China 85 (2005) 610-613
18. Tang J., Li X., Wang N., Zhang S., Lin Q., Li J., and Shi H. Correlation between hypoechoic nodules on ultrasonography and benign hyperplasia in the prostatic outer gland. J Ultrasound Med 24 (2005) 483-488
19. Trojan L., Thomas D., Friedrich D., Grobholz R., Knoll T., Alken P., and Michel M.S. Expression of different vascular endothelial markers in prostate cancer and BPH tissue: An immunohistochemical and clinical evaluation. Anticancer Res 24 (2004) 1651-1656
20. Van de Voorde W.M., Oyen R.H., Van Poppel H.P., Wouters K., Baert L.V., and Lauweryns J.M. Peripherally localized benign hyperplastic nodules of the prostate. Mod Pathol 8 (1995) 46-50
21. Weider N. Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors. Breast Cancer Res Treat 36 (1995) 169-180
22. Wilson S.R., and Burns P.N. Microbubble contrast for radiological imaging: 2. Applications. Ultrasound Q 22 (2006) 15-18