Association of the FABP2 T54 variant with plasma triglycerides and insulin resistance in a multiethnic population

Clinical Chemistry

Volumn 54, Issue 10, 2008, Pages 1742-1744

  De Koning, Lawrence ^a,b   Merchant, Anwar T ^a,b   Hegele, Robert A ^d,e   Xie, Changchun ^a,b   Vuksan, Vlad ^f   Teo, Koon ^a,b,c,d   Yusuf, Salim ^a,b,c,d   Anand, Sonia S ^a,b,c,d,g  

^a MCMASTER UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c HAMILTON HEALTH SCIENCES   (Canada)

^d ROBARTS RESEARCH INSTITUTE   (Canada)

^e UNIVERSITY OF WESTERN ONTARIO   (Canada)

^f UNIVERSITY OF TORONTO   (Canada)

^g HAMILTON GENERAL HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; FATTY ACID BINDING PROTEIN; GLUCOSE; INSULIN; TRIACYLGLYCEROL; FABP2 PROTEIN, HUMAN;

ADULT; ALCOHOL CONSUMPTION; BINDING AFFINITY; BLOOD SAMPLING; BODY MASS; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; ETHNICITY; FATTY ACID TRANSPORT; FEMALE; GENETIC VARIABILITY; GENOTYPE; HEALTH BEHAVIOR; HOMEOSTASIS; HUMAN; INSULIN RESISTANCE; LETTER; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; ORAL GLUCOSE TOLERANCE TEST; PHYSICAL ACTIVITY; TRIACYLGLYCEROL BLOOD LEVEL; BLOOD; CANADA; ETHNIC GROUP; GENETICS; MIDDLE AGED; POPULATION GENETICS;

ADULT; CANADA; ETHNIC GROUPS; FATTY ACID-BINDING PROTEINS; GENETICS, POPULATION; HUMANS; INSULIN RESISTANCE; MIDDLE AGED; TRIGLYCERIDES;

EID: 54049091993     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2008.106682     Document Type: Letter

References (5)

1. Godsland IF, Johnston DG, Chaturvedi N. Mechanisms of disease: lessons from ethnicity in the role of triglyceride metabolism in ischemic heart disease. Nat Clin Pract Endocrinol Metab 2007;3:530-8.
2. Reimann M, Schutte AE, Schwarz PE. Insulin resistance - the role of ethnicity: evidence from Caucasian and African cohorts. Horm Metab Res 2007;39:853-7.
3. Galluzzi JR, Cupples LA, Otvos JD, Wilson PW, Schaefer EJ, Ordovas JM. Association of the A/T54 polymorphism in the intestinal fatty acid binding protein with variations in plasma lipids in the Framingham Offspring Study. Atherosclerosis 2001;159:417-24.
4. Agren JJ, Valve R, Vidgren H, Laakso M, Uusitupa M. Postprandial lipemic response is modified by the polymorphism at codon 54 of the fatty acid-binding protein 2 gene. Arterioscler Thromb Vasc Biol 1998;18:1606-10.
5. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985;28:412-9.