Osteonecrosis of femoral head in the stroke-prone spontaneously hypertensive rats, especially old rats

Clinical and Experimental Hypertension

Volumn 30, Issue 7, 2008, Pages 689-697

  Suzuki, Masahiko ^a   Kumagai, Kenji ^a,b   Osaki, Makoto ^a   Murata, Masakazu ^a   Tomita, Masato ^a   Miyata, Noriaki ^a   Hozumi, Akira ^a   Niwa, Masami ^a  

^a NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

^b NONE   (Japan)

Author keywords

Idiopathic osteonecrosis of the femoral head; Old rats; SHRSP

Indexed keywords

METHYLPREDNISOLONE ACETATE;

ADIPOCYTE; AGED; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE ATROPHY; BONE MARROW; BONE NECROSIS; CARDIOVASCULAR RISK; CELL DEGENERATION; CONTROLLED STUDY; ESSENTIAL HYPERTENSION; FEMORAL HEAD OSTEONECROSIS; FEMUR HEAD; IDIOPATHIC DISEASE; LIFESPAN; MALE; NONHUMAN; PATHOGENESIS; RAT; STROKE; STROKE PRONE SPONTANEOUSLY HYPERTENSIVE RAT;

AGING; ANIMALS; BLOOD PRESSURE; FEMUR HEAD NECROSIS; HYPERTENSION; LIPIDS; MALE; METHYLPREDNISOLONE; OXIDATIVE STRESS; RATS; RATS, INBRED SHR; STROKE;

EID: 54049086944     PISSN: 10641963     EISSN: 15256006     Source Type: Journal    
DOI: 10.1080/10641960802251883     Document Type: Article

References (17)

1. Yamori Y, Horie R, Akiguchi I, Kihara M, Nara Y, Lovenberg W. Symptomatological classification in the development of stroke in stroke-prone spontaneously hypertensive rats. Jpn Circ J. 1982;46:274-283.
2. Hirano T, Iwasaki K, Sagara K, Nishimura Y, Kumashiro T. Necrosis of the femoral head in growing rats. Occlusion of lateral epiphyseal vessels. Acta Orthop Scand. 1989; 60:407-410.
3. Iwasaki K, Hirano T, Sagara K, Nishimura Y. Idiopathic necrosis of the femoral epiphyseal nucleus in rats. Clin Orthop Relat Res. 1992;277:31-40.
4. Kikkawa M, Imai S, Hukuda S. Altered postnatal expression of insulin-like growth factor-I (IGF-I) and type X collagen preceding the Perthes' disease-like lesion of a rat model. J Bone Miner Res. 2000;15:111-119.
5. Shibahara M, Nishida K, Asahara H, Yoshikawa T, Mitani S, Kondo Y, Inoue H. Increased osteocyte apoptosis during the development of femoral head osteonecrosis in spontaneously hypertensive rats. Acta Med Okayama. 2000;54:67-74.
6. Tomita M, Shimokawa I, Maeda H, Higami Y, Kawahara T, Ikeda T, Hirano T. Dietary restriction reduces the prevalence of osteonecrosis of the caput femoris in spontaneously hypertensive rats. Calcif Tissue Int. 1999;64:259-262.
7. Wada M, Kumagai K, Murata M, S-Yamashita Y, Shindo H. Warfarin reduces the incidence of osteonecrosis of the femoral head in spontaneously hypertensive rats. J Orthop Sci. 2004;9:585-590.
8. Naito S, Ito M, Sekine I, Ito M, Hirano T, Iwasaki K, Niwa M. Femoral head necrosis and osteopenia in stroke-prone spontaneously hypertensive rats (SHRSPs). Bone 1993;14:745-753.
9. Murata M, Kumagai K, Miyata N, Osaki M, Shindo H. Osteonecrosis in stroke-prone spontaneously hypertensive rats: Effect of glucocorticoid. J Orthop Sci. 2007;12:289-295.
10. Arlet J. A traumatic necrosis of the femoral head: General report. In: Schoutens A, Arlet J, Gardeniers JWM, Hughes SPF, eds. Bone circulation and vascularization in normal and pathological conditions. New York: Plenum;1993:235.
11. Boss JH, Misselevich I, Bejar J, Norman D, Zinman C, Reis DN. Experimentally gained insight-based proposal apropos the treatment of osteonecrosis of the femoral head. Med Hypotheses. 2004;62:958-965.
12. Peled E, Bejar J, Zinman C, Boss JH. Vasculature deprivation-induced osteonecrosis of rats' femoral heads associated with the formation of deep surface depressions. Arch Orthop Trauma Surg. 2007;127:369-374.
13. Tägil M, Astrand J, Westman L, Aspenberg P, et al. Alendronate prevents collapse in mechanically loaded osteochondral grafts: A bone chamber study in rats. Acta Orthop Scand. 2004;75:756-761.
14. Uygur AM, Alper G, Tahsin B. The effect of steroid use on the pathogenesis of avascular necrosis of the femoral head: An animal model. Acta Orthop Traumatol Turc. 2007;41:58-63.
15. Ichiseki T, Ueda Y, Katsuda S, Kitamura K, Kaneuji A, Matsumoto T. Oxidative stress by glutathione depletion induces osteonecrosis in rats. Rheumatology. 2006;45:287-290.
16. Tsuzawa Y, Funahashi T, Nakamura T. Molecular mechanism of metabolic syndrome X: Contribution of adipocytokines adipocyte-derived bioactive substances. Ann NY Acad Sci. 1999;892:146-154.
17. Uchida Y, Ohba K, Yoshioka T, Irie K, Muraki T, Maru Y. Cellular carbonyl stress enhances the expression of plasminogen activator inhibitor-1 in rat white adipocytes via reactive oxygen species-dependent pathway. Journal of Biological Chemistry. 2004; 279:4075-4083.