Vasculature deprivation-induced osteonecrosis of rats' femoral heads associated with the formation of deep surface depressions

Archives of Orthopaedic and Trauma Surgery

Volumn 127, Issue 5, 2007, Pages 369-374

  Peled, Eli ^a   Bejar, Jacob ^a   Zinman, Chaim ^a   Boss, Jochanan H ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

Avascular osteonecrosis of the femoral head; Drilling of necrotic femoral head; Drilling related depression of femoral head; Rat model of human disease; Spontaneously arising depression of femoral head

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AVASCULAR NECROSIS; BONE BLOOD FLOW; BONE DEFECT; BONE REMODELING; FEMALE; FEMUR HEAD; FEMUR HEAD NECROSIS; FIBROCARTILAGE; HISTOPATHOLOGY; JOINT PRESSURE; NONHUMAN; OSTEOARTHRITIS; PATHOLOGICAL ANATOMY; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; RETROSPECTIVE STUDY; SYNOVIAL FLUID; TISSUE NECROSIS;

ANIMALS; BONE REMODELING; DISEASE MODELS, ANIMAL; FEMALE; FEMUR HEAD; FEMUR HEAD NECROSIS; NEOVASCULARIZATION, PATHOLOGIC; OSTEOGENESIS; RATS; RATS, SPRAGUE-DAWLEY; RETROSPECTIVE STUDIES;

EID: 34250634029     PISSN: 09368051     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00402-006-0258-7     Document Type: Article

References (24)

1. Norman D, Misselevich I, Peled E, Salman S, Boss JH, Zinman C (2004) Intraosseous conduit-induced enhancement of ingrowth of blood vessels into the necrotic femoral head of rats. J Orthopaed Traumatol 4:26-33
2. Leder K, Knahr K (1995) Effect of core decompression in the early stages of necrosis of the femoral head. Orthop Int Edn 3:411-422
3. Norman D, Reis D, Zinman C, Misselevich I, Boss JH (1998) Vascular deprivation-induced necrosis of the femoral head of the rat. An experimental model of avascular osteonecrosis in the skeletally immature individual or Legg-Perthes disease. Int J Exp Pathol 79:173-181
4. Levin D, Norman D, Zinman C, Rubinstein L, Sabo E, Misselevich I, Reis D, Boss JH (1999) Treatment of experimental avascular necrosis of the femoral head with hyperbaric oxygen in rats: Histological evaluation of the femoral heads during the early phase of the reparative process. Exp Mol Pathol 67:99-108
5. Peskin B, Shupak A, Levin D, Norman D, Jacob Z, Boss JH, Misselevich I, Reis DN, Zinman C (2001) Effects of non-weight bearing and hyperbaric oxygen therapy in vascular deprivation-induced osteonecrosis of the rat femoral head. Undersea Hyperb Med 28:187-194
6. Norman D, Miller Y, Sabo E, Misselevich I, Peskin B, Zinman C, Levin D, Reis DN, Boss JH. Rubinstein L, Sabo E, Misselevich I, Reis D, Boss JH (2002) The effects of enoxaparin on the reparative processes in experimental osteonecrosis of the femoral head of the rat. Acta Pathol Microbiol Immunol Scand 110:221-228
7. Boss JH, Misselevich I (2001) Review: Experimental avascular osteonecrosis. Curr Orthop 15:57-67
8. Boss JH, Misselevich I (2003) Osteonecrosis of the femoral head of laboratory animals: The lessons learned from a comparative study of osteonecrosis in man and experimental animals. Vet Pathol 40:345-354
9. Levin D, Norman D, Zinman C, Misselevich I, Reis NR, Boss JH (1999) Osteoarthritis-like disorder in rats with vascular deprivation-induced necrosis of the femoral head. Pathol Res Pract 195:637-642
10. Sokoloff L (1987) Osteoarthritis as a remodeling process. J Rheumatol 14:7-10
11. Jackson DW, Lalor PA, Aberman HM, Simon TM (2001) Spontaneous repair of full-thickness defects of articular cartilage in a goat model. A preliminary study. J Bone Joint Surg 83A:53-64
12. Beck M, Siebenrock KA, Affolter B, Notzli H, Parvizi J, Ganz R (2004) Increased intraarticular pressure reduces blood flow to the femoral head. Clin Orthop 424:149-152
13. Vadasz Z, Misselevich I, Norman D, Peled E, Boss JH (2004) Localization of vascular endothelial growth factor during the early reparative phase of the rats' vessels deprivation-induced osteonecrosis of the femoral heads. Exp Mol Pathol 77:145-148
14. Dürr HD, Martin H, Pellengahr C, Schlemmer M, Maier M, Jansson (2004) The cause of subchondral bone cysts in osteoarthrosis: A finite element analysis. Acta Orthop Scand 75:554-558
15. Huang GS, Chan WP, Chang TC, Chen CY, Yu JS (2003) MR imaging of bone marrow edema and joint effusion in patients with osteonecrosis of the femoral head: Relationship to pain. AJR Am J Roentgenol 181:545-549
16. Crane AR, Scarano JJ (1967) Synovial cysts (ganglia) of bone. Report of two cases. J Bone Joint Surg 49A:355-361
17. Williams HJ, Davies AM, Allen G, Evans N, Mangham DC (2004) Imaging features of intraosseous ganglia: A report of 45 cases. Eur Radiol 14:1761-1769
18. Schmalzried TP, Akizuki KH, Fedenko AN, Mirra J (1997) The role of access of joint fluid to bone in periarticular osteolysis. A report of four cases. J Bone Joint Surg Am 79A:447-452
19. Milgram JW (1983) Morphologic alterations of the subchondral bone in advanced degenerative arthritis. Clin Orthop 173:293-312
20. Ekholm R, Norbäck B (1951) On the relationship between articular changes and function. Acta Orthop Scand 21:81-98
21. Sabokbar A, Crawford R, Murray DW, Athanasou NA (2000) Macrophage-osteoclast differentiation and bone resorption in osteoarthrotic subchondral acetabular cysts. Acta Orthop Scand 71:255-261
22. von Rechenberg B, Leutenegger C, Zlinsky K, McIlwraith CW, Akens MK, Auer JA (2001) Upregulation of mRNA of interleukin-1 and -6 in subchondral cystic lesions of four horses. Equine Vet J 33:143-149
23. Ryu KN, Kim EJ, Yoo MC, Park YK, Sartoris DJ, Resnick D (1997) Ischemic necrosis of the entire femoral head and rapidly destructive hip disease: potential causative relationship. Skeletal Radiol 26:143-149
24. Mont MA, Jones LC, Elias JJ, Inoue N, Yoon TR, Chao EY, Hungerford DS (2001) Strut autografting with and without osteogenic protein-1: A preliminary study of a canine femoral head defect model. J Bone Joint Surg 83A:1013-1022