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Volumn 52, Issue 18, 2008, Pages 1468-1481

Naturally Occurring Human Genetic Variation in the 3′-Untranslated Region of the Secretory Protein Chromogranin A Is Associated With Autonomic Blood Pressure Regulation and Hypertension in a Sex-Dependent Fashion

Author keywords

adrenal; catecholamine; chromaffin; hypertension; sympathetic

Indexed keywords

CATECHOLAMINE; CHROMOGRANIN A; DNA; MESSENGER RNA; SMALL INTERFERING RNA;

EID: 53949122279     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2008.07.047     Document Type: Article
Times cited : (39)

References (74)
  • 1
  • 2
    • 0026680263 scopus 로고
    • The chromogranins A and B: the first 25 years and future perspectives
    • Winkler H., and Fischer-Colbrie R. The chromogranins A and B: the first 25 years and future perspectives. Neuroscience 49 (1992) 497-528
    • (1992) Neuroscience , vol.49 , pp. 497-528
    • Winkler, H.1    Fischer-Colbrie, R.2
  • 3
    • 0025017742 scopus 로고
    • Is physiologic sympathoadrenal catecholamine release exocytotic in humans?
    • Takiyyuddin M.A., Cervenka J.H., Sullivan P.A., et al. Is physiologic sympathoadrenal catecholamine release exocytotic in humans?. Circulation 81 (1990) 185-195
    • (1990) Circulation , vol.81 , pp. 185-195
    • Takiyyuddin, M.A.1    Cervenka, J.H.2    Sullivan, P.A.3
  • 4
    • 0026783755 scopus 로고
    • Calcium and catecholamine interactions with adrenal chromogranins. Comparison of driving forces in binding and aggregation
    • Videen J.S., Mezger M.S., Chang Y.M., and O'Connor D.T. Calcium and catecholamine interactions with adrenal chromogranins. Comparison of driving forces in binding and aggregation. J Biol Chem 267 (1992) 3066-3073
    • (1992) J Biol Chem , vol.267 , pp. 3066-3073
    • Videen, J.S.1    Mezger, M.S.2    Chang, Y.M.3    O'Connor, D.T.4
  • 5
    • 0037024655 scopus 로고    scopus 로고
    • Inositol 1,4,5-trisphosphate receptor/Ca(2+) channel modulatory role of chromogranins A and B
    • Yoo S.H., So S.H., Huh Y.H., and Park H.Y. Inositol 1,4,5-trisphosphate receptor/Ca(2+) channel modulatory role of chromogranins A and B. Ann N Y Acad Sci 971 (2002) 300-310
    • (2002) Ann N Y Acad Sci , vol.971 , pp. 300-310
    • Yoo, S.H.1    So, S.H.2    Huh, Y.H.3    Park, H.Y.4
  • 6
    • 0035943417 scopus 로고    scopus 로고
    • Chromogranin A, an "on/off" switch controlling dense-core secretory granule biogenesis
    • Kim T., Tao-Cheng J.H., Eiden L.E., and Loh Y.P. Chromogranin A, an "on/off" switch controlling dense-core secretory granule biogenesis. Cell 106 (2001) 499-509
    • (2001) Cell , vol.106 , pp. 499-509
    • Kim, T.1    Tao-Cheng, J.H.2    Eiden, L.E.3    Loh, Y.P.4
  • 7
    • 0037024637 scopus 로고    scopus 로고
    • Studies of the dysglycemic peptide, pancreastatin, using a human forearm model
    • Cadman P.E., Rao F., Mahata S.K., and O'Connor D.T. Studies of the dysglycemic peptide, pancreastatin, using a human forearm model. Ann N Y Acad Sci 971 (2002) 528-529
    • (2002) Ann N Y Acad Sci , vol.971 , pp. 528-529
    • Cadman, P.E.1    Rao, F.2    Mahata, S.K.3    O'Connor, D.T.4
  • 8
    • 0023035470 scopus 로고
    • Pancreastatin, a novel pancreatic peptide that inhibits insulin secretion
    • Tatemoto K., Efendic S., Mutt V., Makk G., Feistner G.J., and Barchas J.D. Pancreastatin, a novel pancreatic peptide that inhibits insulin secretion. Nature 324 (1986) 476-478
    • (1986) Nature , vol.324 , pp. 476-478
    • Tatemoto, K.1    Efendic, S.2    Mutt, V.3    Makk, G.4    Feistner, G.J.5    Barchas, J.D.6
  • 9
    • 0029956552 scopus 로고    scopus 로고
    • Antibacterial activity of glycosylated and phosphorylated chromogranin A-derived peptide 173-194 from bovine adrenal medullary chromaffin granules
    • Strub J.M., Goumon Y., Lugardon K., et al. Antibacterial activity of glycosylated and phosphorylated chromogranin A-derived peptide 173-194 from bovine adrenal medullary chromaffin granules. J Biol Chem 271 (1996) 28533-28540
    • (1996) J Biol Chem , vol.271 , pp. 28533-28540
    • Strub, J.M.1    Goumon, Y.2    Lugardon, K.3
  • 10
    • 0027302614 scopus 로고
    • Vasostatins, comprising the N-terminal domain of chromogranin A, suppress tension in isolated human blood vessel segments
    • Aardal S., Helle K.B., Elsayed S., Reed R.K., and Serck-Hanssen G. Vasostatins, comprising the N-terminal domain of chromogranin A, suppress tension in isolated human blood vessel segments. J Neuroendocrinol 5 (1993) 405-412
    • (1993) J Neuroendocrinol , vol.5 , pp. 405-412
    • Aardal, S.1    Helle, K.B.2    Elsayed, S.3    Reed, R.K.4    Serck-Hanssen, G.5
  • 11
    • 0033613966 scopus 로고    scopus 로고
    • Desensitization of catecholamine release. The novel catecholamine release-inhibitory peptide catestatin (chromogranin a344-364) acts at the receptor to prevent nicotinic cholinergic tolerance
    • Mahata S.K., Mahata M., Parmer R.J., and O'Connor D.T. Desensitization of catecholamine release. The novel catecholamine release-inhibitory peptide catestatin (chromogranin a344-364) acts at the receptor to prevent nicotinic cholinergic tolerance. J Biol Chem 274 (1999) 2920-2928
    • (1999) J Biol Chem , vol.274 , pp. 2920-2928
    • Mahata, S.K.1    Mahata, M.2    Parmer, R.J.3    O'Connor, D.T.4
  • 12
    • 0030803637 scopus 로고    scopus 로고
    • Novel autocrine feedback control of catecholamine release. A discrete chromogranin a fragment is a noncompetitive nicotinic cholinergic antagonist
    • Mahata S.K., O'Connor D.T., Mahata M., et al. Novel autocrine feedback control of catecholamine release. A discrete chromogranin a fragment is a noncompetitive nicotinic cholinergic antagonist. J Clin Invest 100 (1997) 1623-1633
    • (1997) J Clin Invest , vol.100 , pp. 1623-1633
    • Mahata, S.K.1    O'Connor, D.T.2    Mahata, M.3
  • 13
    • 0028090414 scopus 로고
    • Genetic dissection of complex traits
    • Lander E.S., and Schork N.J. Genetic dissection of complex traits. Science 265 (1994) 2037-2048
    • (1994) Science , vol.265 , pp. 2037-2048
    • Lander, E.S.1    Schork, N.J.2
  • 14
    • 0026081016 scopus 로고
    • Chromogranin A storage and secretion: sensitivity and specificity for the diagnosis of pheochromocytoma
    • Hsiao R.J., Parmer R.J., Takiyyuddin M.A., and O'Connor D.T. Chromogranin A storage and secretion: sensitivity and specificity for the diagnosis of pheochromocytoma. Medicine (Baltimore) 70 (1991) 33-45
    • (1991) Medicine (Baltimore) , vol.70 , pp. 33-45
    • Hsiao, R.J.1    Parmer, R.J.2    Takiyyuddin, M.A.3    O'Connor, D.T.4
  • 15
    • 0021839129 scopus 로고
    • Plasma chromogranin A. Initial studies in human hypertension
    • O'Connor D.T. Plasma chromogranin A. Initial studies in human hypertension. Hypertension 7 (1985) I76-I79
    • (1985) Hypertension , vol.7
    • O'Connor, D.T.1
  • 17
    • 0029071546 scopus 로고
    • Chromogranin A in human hypertension. Influence of heredity
    • Takiyyuddin M.A., Parmer R.J., Kailasam M.T., et al. Chromogranin A in human hypertension. Influence of heredity. Hypertension 26 (1995) 213-220
    • (1995) Hypertension , vol.26 , pp. 213-220
    • Takiyyuddin, M.A.1    Parmer, R.J.2    Kailasam, M.T.3
  • 18
    • 0033507145 scopus 로고    scopus 로고
    • Catecholamine storage vesicle protein expression in genetic hypertension
    • O'Connor D.T., Takiyyuddin M.A., Printz M.P., et al. Catecholamine storage vesicle protein expression in genetic hypertension. Blood Press 8 (1999) 285-295
    • (1999) Blood Press , vol.8 , pp. 285-295
    • O'Connor, D.T.1    Takiyyuddin, M.A.2    Printz, M.P.3
  • 19
    • 0026654476 scopus 로고
    • Chromogranin A correlates with norepinephrine release rate
    • Dimsdale J.E., O'Connor D.T., Ziegler M., and Mills P. Chromogranin A correlates with norepinephrine release rate. Life Sci 51 (1992) 519-525
    • (1992) Life Sci , vol.51 , pp. 519-525
    • Dimsdale, J.E.1    O'Connor, D.T.2    Ziegler, M.3    Mills, P.4
  • 20
    • 22144495740 scopus 로고    scopus 로고
    • Hypertension from targeted ablation of chromogranin A can be rescued by the human ortholog
    • Mahapatra N.R., O'Connor D.T., Vaingankar S.M., et al. Hypertension from targeted ablation of chromogranin A can be rescued by the human ortholog. J Clin Invest 115 (2005) 1942-1952
    • (2005) J Clin Invest , vol.115 , pp. 1942-1952
    • Mahapatra, N.R.1    O'Connor, D.T.2    Vaingankar, S.M.3
  • 21
    • 10744224429 scopus 로고    scopus 로고
    • Both rare and common polymorphisms contribute functional variation at CHGA, a regulator of catecholamine physiology
    • Wen G., Mahata S.K., Cadman P., et al. Both rare and common polymorphisms contribute functional variation at CHGA, a regulator of catecholamine physiology. Am J Hum Genet 74 (2004) 197-207
    • (2004) Am J Hum Genet , vol.74 , pp. 197-207
    • Wen, G.1    Mahata, S.K.2    Cadman, P.3
  • 22
    • 0030877937 scopus 로고    scopus 로고
    • Development and validation of a noninvasive method to determine arterial pressure and vascular compliance
    • Brinton T.J., Cotter B., Kailasam M.T., et al. Development and validation of a noninvasive method to determine arterial pressure and vascular compliance. Am J Cardiol 80 (1997) 323-330
    • (1997) Am J Cardiol , vol.80 , pp. 323-330
    • Brinton, T.J.1    Cotter, B.2    Kailasam, M.T.3
  • 23
    • 33847609151 scopus 로고    scopus 로고
    • Population-based sample reveals gene-gender interactions in blood pressure in white Americans
    • Rana B.K., Insel P.A., Payne S.H., et al. Population-based sample reveals gene-gender interactions in blood pressure in white Americans. Hypertension 49 (2007) 96-106
    • (2007) Hypertension , vol.49 , pp. 96-106
    • Rana, B.K.1    Insel, P.A.2    Payne, S.H.3
  • 24
    • 0037109598 scopus 로고    scopus 로고
    • Prevalence of coronary heart disease associated with HFE mutations in adults attending a health appraisal center
    • Waalen J., Felitti V., Gelbart T., Ho N.J., and Beutler E. Prevalence of coronary heart disease associated with HFE mutations in adults attending a health appraisal center. Am J Med 113 (2002) 472-479
    • (2002) Am J Med , vol.113 , pp. 472-479
    • Waalen, J.1    Felitti, V.2    Gelbart, T.3    Ho, N.J.4    Beutler, E.5
  • 25
    • 33646164662 scopus 로고    scopus 로고
    • Rho kinase polymorphism influences blood pressure and systemic vascular resistance in human twins: role of heredity
    • Seasholtz T.M., Wessel J., Rao F., et al. Rho kinase polymorphism influences blood pressure and systemic vascular resistance in human twins: role of heredity. Hypertension 47 (2006) 937-947
    • (2006) Hypertension , vol.47 , pp. 937-947
    • Seasholtz, T.M.1    Wessel, J.2    Rao, F.3
  • 26
    • 12244264435 scopus 로고    scopus 로고
    • Genetic power calculator: design of linkage and association genetic mapping studies of complex traits
    • Purcell S., Cherny S.S., and Sham P.C. Genetic power calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics 19 (2003) 149-150
    • (2003) Bioinformatics , vol.19 , pp. 149-150
    • Purcell, S.1    Cherny, S.S.2    Sham, P.C.3
  • 27
    • 0033759719 scopus 로고    scopus 로고
    • Linkage disequilibrium analysis of biallelic DNA markers, human quantitative trait loci, and threshold-defined case and control subjects
    • Schork N.J., Nath S.K., Fallin D., and Chakravarti A. Linkage disequilibrium analysis of biallelic DNA markers, human quantitative trait loci, and threshold-defined case and control subjects. Am J Hum Genet 67 (2000) 1208-1218
    • (2000) Am J Hum Genet , vol.67 , pp. 1208-1218
    • Schork, N.J.1    Nath, S.K.2    Fallin, D.3    Chakravarti, A.4
  • 28
    • 19944389519 scopus 로고    scopus 로고
    • Functional allelic heterogeneity and pleiotropy of a repeat polymorphism in tyrosine hydroxylase: prediction of catecholamines and response to stress in twins
    • Zhang L., Rao F., Wessel J., et al. Functional allelic heterogeneity and pleiotropy of a repeat polymorphism in tyrosine hydroxylase: prediction of catecholamines and response to stress in twins. Physiol Genomics 19 (2004) 277-291
    • (2004) Physiol Genomics , vol.19 , pp. 277-291
    • Zhang, L.1    Rao, F.2    Wessel, J.3
  • 29
    • 33646756856 scopus 로고    scopus 로고
    • Pleiotropic effects of novel trans-acting loci influencing human sympathochromaffin secretion
    • Greenwood T.A., Rao F., Stridsberg M., et al. Pleiotropic effects of novel trans-acting loci influencing human sympathochromaffin secretion. Physiol Genomics 25 (2006) 470-479
    • (2006) Physiol Genomics , vol.25 , pp. 470-479
    • Greenwood, T.A.1    Rao, F.2    Stridsberg, M.3
  • 30
    • 33846100236 scopus 로고    scopus 로고
    • C-reactive protein, an 'intermediate phenotype' for inflammation: human twin studies reveal heritability, association with blood pressure and the metabolic syndrome, and the influence of common polymorphism at catecholaminergic/beta-adrenergic pathway loci
    • Wessel J., Moratorio G., Rao F., et al. C-reactive protein, an 'intermediate phenotype' for inflammation: human twin studies reveal heritability, association with blood pressure and the metabolic syndrome, and the influence of common polymorphism at catecholaminergic/beta-adrenergic pathway loci. J Hypertens 25 (2007) 329-343
    • (2007) J Hypertens , vol.25 , pp. 329-343
    • Wessel, J.1    Moratorio, G.2    Rao, F.3
  • 31
    • 0036628754 scopus 로고    scopus 로고
    • Early decline in the catecholamine release-inhibitory peptide catestatin in humans at genetic risk of hypertension
    • O'Connor D.T., Kailasam M.T., Kennedy B.P., Ziegler M.G., Yanaihara N., and Parmer R.J. Early decline in the catecholamine release-inhibitory peptide catestatin in humans at genetic risk of hypertension. J Hypertens 20 (2002) 1335-1345
    • (2002) J Hypertens , vol.20 , pp. 1335-1345
    • O'Connor, D.T.1    Kailasam, M.T.2    Kennedy, B.P.3    Ziegler, M.G.4    Yanaihara, N.5    Parmer, R.J.6
  • 32
    • 0031853152 scopus 로고    scopus 로고
    • Arterial response during cold pressor test in borderline hypertension
    • Lafleche A.B., Pannier B.M., Laloux B., and Safar M.E. Arterial response during cold pressor test in borderline hypertension. Am J Physiol 275 (1998) H409-H415
    • (1998) Am J Physiol , vol.275
    • Lafleche, A.B.1    Pannier, B.M.2    Laloux, B.3    Safar, M.E.4
  • 33
    • 0028942227 scopus 로고
    • Relation between cold pressor test and development of hypertension based on 28-year follow-up
    • Kasagi F., Akahoshi M., and Shimaoka K. Relation between cold pressor test and development of hypertension based on 28-year follow-up. Hypertension 25 (1995) 71-76
    • (1995) Hypertension , vol.25 , pp. 71-76
    • Kasagi, F.1    Akahoshi, M.2    Shimaoka, K.3
  • 34
    • 0034471927 scopus 로고    scopus 로고
    • Measurements of chromogranins and chromogranin-related peptides by immunological methods
    • Stridsberg M. Measurements of chromogranins and chromogranin-related peptides by immunological methods. Adv Exp Med Biol 482 (2000) 319-327
    • (2000) Adv Exp Med Biol , vol.482 , pp. 319-327
    • Stridsberg, M.1
  • 35
    • 0034047119 scopus 로고    scopus 로고
    • Characterisation of N-terminal chromogranin A and chromogranin B in mammals by region-specific radioimmunoassays and chromatographic separation methods
    • Stridsberg M., Angeletti R.H., and Helle K.B. Characterisation of N-terminal chromogranin A and chromogranin B in mammals by region-specific radioimmunoassays and chromatographic separation methods. J Endocrinol 165 (2000) 703-714
    • (2000) J Endocrinol , vol.165 , pp. 703-714
    • Stridsberg, M.1    Angeletti, R.H.2    Helle, K.B.3
  • 36
    • 0028874025 scopus 로고
    • Measurements of chromogranin A, chromogranin B (secretogranin I), chromogranin C (secretogranin II) and pancreastatin in plasma and urine from patients with carcinoid tumours and endocrine pancreatic tumours
    • Stridsberg M., Oberg K., Li Q., Engstrom U., and Lundqvist G. Measurements of chromogranin A, chromogranin B (secretogranin I), chromogranin C (secretogranin II) and pancreastatin in plasma and urine from patients with carcinoid tumours and endocrine pancreatic tumours. J Endocrinol 144 (1995) 49-59
    • (1995) J Endocrinol , vol.144 , pp. 49-59
    • Stridsberg, M.1    Oberg, K.2    Li, Q.3    Engstrom, U.4    Lundqvist, G.5
  • 37
    • 0025641583 scopus 로고
    • A more sensitive and specific radioenzymatic assay for catecholamines
    • Kennedy B., and Ziegler M.G. A more sensitive and specific radioenzymatic assay for catecholamines. Life Sci 47 (1990) 2143-2153
    • (1990) Life Sci , vol.47 , pp. 2143-2153
    • Kennedy, B.1    Ziegler, M.G.2
  • 38
    • 0033624287 scopus 로고    scopus 로고
    • Beta2-adrenergic receptor polymorphisms at codon 16, cardiovascular phenotypes and essential hypertension in whites and African Americans
    • Herrmann V., Buscher R., Go M.M., et al. Beta2-adrenergic receptor polymorphisms at codon 16, cardiovascular phenotypes and essential hypertension in whites and African Americans. Am J Hypertens 13 (2000) 1021-1026
    • (2000) Am J Hypertens , vol.13 , pp. 1021-1026
    • Herrmann, V.1    Buscher, R.2    Go, M.M.3
  • 39
    • 0035895258 scopus 로고    scopus 로고
    • High-throughput development and characterization of a genomewide collection of gene-based single nucleotide polymorphism markers by chip-based matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
    • Buetow K.H., Edmonson M., MacDonald R., et al. High-throughput development and characterization of a genomewide collection of gene-based single nucleotide polymorphism markers by chip-based matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Proc Natl Acad Sci U S A 98 (2001) 581-584
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 581-584
    • Buetow, K.H.1    Edmonson, M.2    MacDonald, R.3
  • 40
    • 28644434277 scopus 로고    scopus 로고
    • Pyrosequencing: history, biochemistry and future
    • Ahmadian A., Ehn M., and Hober S. Pyrosequencing: history, biochemistry and future. Clin Chim Acta 363 (2006) 83-94
    • (2006) Clin Chim Acta , vol.363 , pp. 83-94
    • Ahmadian, A.1    Ehn, M.2    Hober, S.3
  • 41
    • 0345704610 scopus 로고
    • Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
    • Greene L.A., and Tischler A.S. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci U S A 73 (1976) 2424-2428
    • (1976) Proc Natl Acad Sci U S A , vol.73 , pp. 2424-2428
    • Greene, L.A.1    Tischler, A.S.2
  • 42
    • 0034017850 scopus 로고    scopus 로고
    • GOLD-graphical overview of linkage disequilibrium
    • Abecasis G.R., and Cookson W.O. GOLD-graphical overview of linkage disequilibrium. Bioinformatics 16 (2000) 182-183
    • (2000) Bioinformatics , vol.16 , pp. 182-183
    • Abecasis, G.R.1    Cookson, W.O.2
  • 43
    • 0035154452 scopus 로고    scopus 로고
    • Genetic analysis of case/control data using estimated haplotype frequencies: application to APOE locus variation and Alzheimer's disease
    • Fallin D., Cohen A., Essioux L., et al. Genetic analysis of case/control data using estimated haplotype frequencies: application to APOE locus variation and Alzheimer's disease. Genome Res 11 (2001) 143-151
    • (2001) Genome Res , vol.11 , pp. 143-151
    • Fallin, D.1    Cohen, A.2    Essioux, L.3
  • 44
    • 0036284203 scopus 로고    scopus 로고
    • Testing association of statistically inferred haplotypes with discrete and continuous traits in samples of unrelated individuals
    • Zaykin D.V., Westfall P.H., Young S.S., Karnoub M.A., Wagner M.J., and Ehm M.G. Testing association of statistically inferred haplotypes with discrete and continuous traits in samples of unrelated individuals. Hum Hered 53 (2002) 79-91
    • (2002) Hum Hered , vol.53 , pp. 79-91
    • Zaykin, D.V.1    Westfall, P.H.2    Young, S.S.3    Karnoub, M.A.4    Wagner, M.J.5    Ehm, M.G.6
  • 45
    • 4444367508 scopus 로고    scopus 로고
    • Haplotype reconstruction from genotype data using imperfect phylogeny
    • Halperin E., and Eskin E. Haplotype reconstruction from genotype data using imperfect phylogeny. Bioinformatics 20 (2004) 1842-1849
    • (2004) Bioinformatics , vol.20 , pp. 1842-1849
    • Halperin, E.1    Eskin, E.2
  • 46
    • 0027849290 scopus 로고
    • A remark on algorithm 643: FEXACT: an algorithm for performing Fisher's exact test in R×C contingency tables
    • Clarkson D., Fan Y.-A., and Joe H. A remark on algorithm 643: FEXACT: an algorithm for performing Fisher's exact test in R×C contingency tables. ACM Transactions on Mathematical Software 19 (1993) 484-488
    • (1993) ACM Transactions on Mathematical Software , vol.19 , pp. 484-488
    • Clarkson, D.1    Fan, Y.-A.2    Joe, H.3
  • 47
    • 1842539516 scopus 로고    scopus 로고
    • A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other
    • Nyholt D.R. A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am J Hum Genet 74 (2004) 765-769
    • (2004) Am J Hum Genet , vol.74 , pp. 765-769
    • Nyholt, D.R.1
  • 48
    • 67649345185 scopus 로고
    • An improved Bonferroni procedure for multiple test of significance
    • Simes R.J. An improved Bonferroni procedure for multiple test of significance. Biometrika 73 (1986) 751-754
    • (1986) Biometrika , vol.73 , pp. 751-754
    • Simes, R.J.1
  • 49
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: a practical and powerful approach to multiple testing
    • Benjamini Y., and Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Ser B (Methodological) 57 (1995) 289-300
    • (1995) J R Stat Soc Ser B (Methodological) , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 50
    • 0031966959 scopus 로고    scopus 로고
    • Multipoint quantitative-trait linkage analysis in general pedigrees
    • Almasy L., and Blangero J. Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet 62 (1998) 1198-1211
    • (1998) Am J Hum Genet , vol.62 , pp. 1198-1211
    • Almasy, L.1    Blangero, J.2
  • 51
    • 0034657115 scopus 로고    scopus 로고
    • Genetic analysis of the age at menopause by using estimating equations and Bayesian random effects models
    • Do K.A., Broom B.M., Kuhnert P., et al. Genetic analysis of the age at menopause by using estimating equations and Bayesian random effects models. Stat Med 19 (2000) 1217-1235
    • (2000) Stat Med , vol.19 , pp. 1217-1235
    • Do, K.A.1    Broom, B.M.2    Kuhnert, P.3
  • 52
    • 33747821745 scopus 로고    scopus 로고
    • RegRNA: an integrated web server for identifying regulatory RNA motifs and elements
    • Huang H.Y., Chien C.H., Jen K.H., and Huang H.D. RegRNA: an integrated web server for identifying regulatory RNA motifs and elements. Nucleic Acids Res 34 (2006) W429-W434
    • (2006) Nucleic Acids Res , vol.34
    • Huang, H.Y.1    Chien, C.H.2    Jen, K.H.3    Huang, H.D.4
  • 53
    • 0033591465 scopus 로고    scopus 로고
    • Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure
    • Mathews D.H., Sabina J., Zuker M., and Turner D.H. Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure. J Mol Biol 288 (1999) 911-940
    • (1999) J Mol Biol , vol.288 , pp. 911-940
    • Mathews, D.H.1    Sabina, J.2    Zuker, M.3    Turner, D.H.4
  • 54
    • 0036842012 scopus 로고    scopus 로고
    • Genomic association/linkage of sodium lithium countertransport in CEPH pedigrees
    • Schork N.J., Gardner J.P., Zhang L., et al. Genomic association/linkage of sodium lithium countertransport in CEPH pedigrees. Hypertension 40 (2002) 619-628
    • (2002) Hypertension , vol.40 , pp. 619-628
    • Schork, N.J.1    Gardner, J.P.2    Zhang, L.3
  • 55
    • 0020117867 scopus 로고
    • Physiological aspects of primary hypertension
    • Folkow B. Physiological aspects of primary hypertension. Physiol Rev 62 (1982) 347-504
    • (1982) Physiol Rev , vol.62 , pp. 347-504
    • Folkow, B.1
  • 56
    • 0034491799 scopus 로고    scopus 로고
    • SIMCOAL: a general coalescent program for the simulation of molecular data in interconnected populations with arbitrary demography
    • Excoffier L., Novembre J., and Schneider S. SIMCOAL: a general coalescent program for the simulation of molecular data in interconnected populations with arbitrary demography. J Hered 91 (2000) 506-509
    • (2000) J Hered , vol.91 , pp. 506-509
    • Excoffier, L.1    Novembre, J.2    Schneider, S.3
  • 57
    • 21044446071 scopus 로고    scopus 로고
    • Human response to alpha2-adrenergic agonist stimulation studied in an isolated vascular bed in vivo: biphasic influence of dose, age, gender, and receptor genotype
    • King D., Etzel J.P., Chopra S., et al. Human response to alpha2-adrenergic agonist stimulation studied in an isolated vascular bed in vivo: biphasic influence of dose, age, gender, and receptor genotype. Clin Pharmacol Ther 77 (2005) 388-403
    • (2005) Clin Pharmacol Ther , vol.77 , pp. 388-403
    • King, D.1    Etzel, J.P.2    Chopra, S.3
  • 58
    • 0033809769 scopus 로고    scopus 로고
    • Gender differences in sensitivity to adrenergic agonists of forearm resistance vasculature
    • Kneale B.J., Chowienczyk P.J., Brett S.E., Coltart D.J., and Ritter J.M. Gender differences in sensitivity to adrenergic agonists of forearm resistance vasculature. J Am Coll Cardiol 36 (2000) 1233-1238
    • (2000) J Am Coll Cardiol , vol.36 , pp. 1233-1238
    • Kneale, B.J.1    Chowienczyk, P.J.2    Brett, S.E.3    Coltart, D.J.4    Ritter, J.M.5
  • 59
    • 0031922716 scopus 로고    scopus 로고
    • Cardiovascular reactivity to video game predicts subsequent blood pressure increases in young men: the CARDIA study
    • Markovitz J.H., Raczynski J.M., Wallace D., Chettur V., and Chesney M.A. Cardiovascular reactivity to video game predicts subsequent blood pressure increases in young men: the CARDIA study. Psychosom Med 60 (1998) 186-191
    • (1998) Psychosom Med , vol.60 , pp. 186-191
    • Markovitz, J.H.1    Raczynski, J.M.2    Wallace, D.3    Chettur, V.4    Chesney, M.A.5
  • 61
    • 0038307297 scopus 로고    scopus 로고
    • Androgens and cardiovascular disease
    • Liu P.Y., Death A.K., and Handelsman D.J. Androgens and cardiovascular disease. Endocr Rev 24 (2003) 313-340
    • (2003) Endocr Rev , vol.24 , pp. 313-340
    • Liu, P.Y.1    Death, A.K.2    Handelsman, D.J.3
  • 62
    • 0024416661 scopus 로고
    • Cardiovascular reactivity to the cold pressor test as a predictor of hypertension
    • Menkes M.S., Matthews K.A., Krantz D.S., et al. Cardiovascular reactivity to the cold pressor test as a predictor of hypertension. Hypertension 14 (1989) 524-530
    • (1989) Hypertension , vol.14 , pp. 524-530
    • Menkes, M.S.1    Matthews, K.A.2    Krantz, D.S.3
  • 63
    • 0035714529 scopus 로고    scopus 로고
    • Gender differences in the regulation of blood pressure
    • Reckelhoff J.F. Gender differences in the regulation of blood pressure. Hypertension 37 (2001) 1199-1208
    • (2001) Hypertension , vol.37 , pp. 1199-1208
    • Reckelhoff, J.F.1
  • 64
    • 0347601668 scopus 로고    scopus 로고
    • Cardiovascular haemodynamic response to repeated mental stress in normotensive subjects at genetic risk of hypertension: evidence of enhanced reactivity, blunted adaptation, and delayed recovery
    • Schneider G.M., Jacobs D.W., Gevirtz R.N., and O'Connor D.T. Cardiovascular haemodynamic response to repeated mental stress in normotensive subjects at genetic risk of hypertension: evidence of enhanced reactivity, blunted adaptation, and delayed recovery. J Hum Hypertens 17 (2003) 829-840
    • (2003) J Hum Hypertens , vol.17 , pp. 829-840
    • Schneider, G.M.1    Jacobs, D.W.2    Gevirtz, R.N.3    O'Connor, D.T.4
  • 66
    • 0035220161 scopus 로고    scopus 로고
    • The future of genetic case-control studies
    • Schork N.J., Fallin D., Thiel B., et al. The future of genetic case-control studies. Adv Genet 42 (2001) 191-212
    • (2001) Adv Genet , vol.42 , pp. 191-212
    • Schork, N.J.1    Fallin, D.2    Thiel, B.3
  • 67
    • 33644979662 scopus 로고    scopus 로고
    • Early phenotypic changes in hypertension: a role for the autonomic nervous system and heredity
    • Lillie E.O., and O'Connor D.T. Early phenotypic changes in hypertension: a role for the autonomic nervous system and heredity. Hypertension 47 (2006) 331-333
    • (2006) Hypertension , vol.47 , pp. 331-333
    • Lillie, E.O.1    O'Connor, D.T.2
  • 69
    • 0034135982 scopus 로고    scopus 로고
    • Heredity and the autonomic nervous system in human hypertension
    • O'Connor D.T., Insel P.A., Ziegler M.G., et al. Heredity and the autonomic nervous system in human hypertension. Curr Hypertens Rep 2 (2000) 16-22
    • (2000) Curr Hypertens Rep , vol.2 , pp. 16-22
    • O'Connor, D.T.1    Insel, P.A.2    Ziegler, M.G.3
  • 70
    • 31144448042 scopus 로고    scopus 로고
    • AU-rich elements and associated factors: are there unifying principles?
    • Barreau C., Paillard L., and Osborne H.B. AU-rich elements and associated factors: are there unifying principles?. Nucleic Acids Res 33 (2005) 7138-7150
    • (2005) Nucleic Acids Res , vol.33 , pp. 7138-7150
    • Barreau, C.1    Paillard, L.2    Osborne, H.B.3
  • 71
    • 0142135190 scopus 로고    scopus 로고
    • Chromogranin B-induced secretory granule biogenesis: comparison with the similar role of chromogranin A
    • Huh Y.H., Jeon S.H., and Yoo S.H. Chromogranin B-induced secretory granule biogenesis: comparison with the similar role of chromogranin A. J Biol Chem 278 (2003) 40581-40589
    • (2003) J Biol Chem , vol.278 , pp. 40581-40589
    • Huh, Y.H.1    Jeon, S.H.2    Yoo, S.H.3
  • 72
    • 0028307990 scopus 로고
    • Sympatho-adrenal secretion in humans: factors governing catecholamine and storage vesicle peptide co-release
    • Takiyyuddin M.A., Brown M.R., Dinh T.Q., et al. Sympatho-adrenal secretion in humans: factors governing catecholamine and storage vesicle peptide co-release. J Auton Pharmacol 14 (1994) 187-200
    • (1994) J Auton Pharmacol , vol.14 , pp. 187-200
    • Takiyyuddin, M.A.1    Brown, M.R.2    Dinh, T.Q.3
  • 73
    • 0023838230 scopus 로고
    • Enkephalins in human phaeochromocytomas: localization in immunoreactive, high molecular weight form to the soluble core of chromaffin granules
    • Parmer R.J., and O'Connor D.T. Enkephalins in human phaeochromocytomas: localization in immunoreactive, high molecular weight form to the soluble core of chromaffin granules. J Hypertens 6 (1988) 187-198
    • (1988) J Hypertens , vol.6 , pp. 187-198
    • Parmer, R.J.1    O'Connor, D.T.2
  • 74
    • 0035451780 scopus 로고    scopus 로고
    • On the allelic spectrum of human disease
    • Reich D.E., and Lander E.S. On the allelic spectrum of human disease. Trends Genet 17 (2001) 502-510
    • (2001) Trends Genet , vol.17 , pp. 502-510
    • Reich, D.E.1    Lander, E.S.2


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