Modulating activity in the motor cortex affects performance for the two hands differently depending upon which hemisphere is stimulated

European Journal of Neuroscience

Volumn 28, Issue 8, 2008, Pages 1667-1673

  Vines, Bradley W ^a,b   Nair, Dinesh ^a   Schlaug, Gottfried ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Human; Motor; Rehabilitation; Stroke; Transcranial direct current stimulation

Indexed keywords

ARTICLE; BRAIN ASYMMETRY; BRAIN DEPTH STIMULATION; CONTROLLED STUDY; HAND MOVEMENT; HUMAN; HUMAN EXPERIMENT; MOTOR ACTIVITY; MOTOR COORDINATION; MOTOR CORTEX; NERVE EXCITABILITY; NORMAL HUMAN; PRIORITY JOURNAL; TASK PERFORMANCE;

ACTION POTENTIALS; ADULT; CORPUS CALLOSUM; DOMINANCE, CEREBRAL; ELECTRIC STIMULATION; EVOKED POTENTIALS, MOTOR; FUNCTIONAL LATERALITY; HAND; HUMANS; MOTOR CORTEX; MOTOR SKILLS; MOVEMENT; NEURAL PATHWAYS; NEURONS; NEUROPSYCHOLOGICAL TESTS; PSYCHOMOTOR PERFORMANCE;

EID: 53949107495     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2008.06459.x     Document Type: Article

References (45)

1. Boggio, P.S., Castro, L.O., Savagim, E.A., Braite, R., Cruz, V.C., Rocha, R.R., Rigonatti, S.P., Silva, M.T. Fregni, F. (2006) Enhancement of non-dominant hand motor function by anodal transcranial direct current stimulation. Neurosci. Lett., 404, 232 236.
2. Duque, J., Murase, N., Celnik, P., Hummel, F., Harris-Love, M., Mazzocchio, R., Olivier, E. Cohen, L.G. (2007) Intermanual differences in movement-related interhemispheric inhibition. J. Cogn. Neurosci., 19, 204 213.
3. Ferbert, A., Priori, A., Rothwell, J.C., Day, B.L., Colebatch, J.G. Marsden, C.D. (1992) Interhemispheric inhibition of the human motor cortex. J. Physiol., 453, 525 546.
4. Fregni, F., Boggio, P.S., Mansur, C.G., Wagner, T., Ferreira, M.J., Lima, M.C., Rigonatti, S.P., Marcolin, M.A., Freedman, S.D., Nitsche, M.A. Pascual-Leone, A. (2005) Transcranial direct current stimulation of the unaffected hemisphere in stroke patients. Neuroreport, 16, 1551 1555.
5. Gandiga, P.C., Hummel, F.C. Cohen, L.G. (2006) Transcranial DC stimulation (tDCS): a tool for double-blind sham-controlled clinical studies in brain stimulation. Clin. Neurophysiol., 117, 845 850.
6. Garry, M.I., Kamen, G. Nordstrom, M.A. (2004) Hemispheric differences in the relationship between corticomotor excitability changes following a fine-motor task and motor learning. J. Neurophysiol., 91, 1570 1578.
7. Gilio, F., Rizzo, V., Siebner, H.R. Rothwell, J.C. (2003) Effects on the right motor hand-area excitability produced by low-frequency rTMS over human contralateral homologous cortex. J. Physiol., 551, 563 573.
8. Gorsler, A., Bäumer, T., Weiller, C., Münchau, A. Liepert, J. (2003) Interhemispheric effects of high and low frequency rTMS in healthy humans. Clin. Neurophysiol., 114, 1800 1807.
9. Halsband, U. (1992) Left-hemisphere preponderance in trajectorial learning. Neuroreport, 3, 397 400.
10. Herwig, U., Satrapi, P. Schonfeldt-Lecuona, C. (2003) Using the international 10-20 EEG system for positioning of transcranial magnetic stimulation. Brain Topogr., 16, 95 99.
11. Homan, R.W., Herman, J. Purdy, P. (1987) Cerebral location of international 10-20 system electrode placement. Electroencephalogr. Clin. Neurophysiol., 66, 376 382.
12. Hummel, F. Cohen, L.G. (2006) Non-invasive brain stimulation: a new strategy to improve neurorehabilitation after stroke? Lancet Neurol., 5, 708 712.
13. Hummel, F., Celnik, P., Giraux, P., Floel, A., Wu, W., Gerloff, C. Cohen, L.G. (2005) Effects of non-invasive cortical stimulation on skilled motor function in chronic stroke. Brain, 128, 490 499.
14. Iyer, M.B., Mattu, U., Grafman, J., Lomarev, M., Sato, S. Wassermann, E.M. (2005) Safety and cognitive effect of frontal DC brain polarization in healthy individuals. Neurology, 64, 872 875.
15. Jäncke, L., Steinmetz, H., Benilow, S. Ziemann, U. (2004) Slowing fastest finger movements of the dominant hand with low-frequency rTMS of the hand area of the primary motor cortex. Exp. Brain Res., 155, 196 203.
16. Kincses, T.Z., Antal, A., Nitsche, M.A., Bártfai, O. Paulus, W. (2003) Facilitation of probabilistic classification learning by transcranial direct current stimulation of the prefrontal cortex in the human. Neuropsychologia, 42, 113 117.
17. Kobayashi, M., Hutchinson, S., Schlaug, G. Pascual-Leone, A. (2004) Ipsilateral motor cortex activation on functional magnetic resonance imaging during unilateral hand movements is related to interhemispheric interactions. Neuroimage, 20, 2259 2270.
18. Koeneke, S., Lutz, K., Herwig, U., Ziemann, U. Jancke, L. (2006) Extensive training of elementary finger tapping movements changes the pattern of motor cortex excitability. Exp. Brain Res., 174, 199 209.
19. Koski, L. Dobkin, B.H. (2005) Standardizing and validating transcranial magnetic stimulation measures for use in stroke rehabilitation research. Clin. Neurophysiol., 116, 740 741.
20. Levit-Binnun, N., Handzy, N.Z., Peled, A., Modai, I. Moses, E. (2007) Transcranial magnetic stimulation in a finger-tapping task separates motor from timing mechanisms and induces frequency doubling. J. Cogn. Neurosci., 19, 721 733.
21. Liebetanz, D., Nitsche, M.A., Tergau, F. Paulus, W. (2002) Pharmacological approach to the mechanisms of transcranial DC-stimulation- induced after-effects of human motor cortex excitability. Brain, 125, 2238 2247.
22. Mansur, C.G., Fregni, F., Boggio, P.S., Riberto, M., Gallucci-Neto, J., Santos, C.M., Wagner, T., Rigonatti, S.P., Marcolin, M.A. Pascual-Leone, A. (2005) A sham stimulation-controlled trial of rTMS of the unaffected hemisphere in stroke patients. Neurology, 64, 1802 1804.
23. Muellbacher, W., Ziemann, U., Boroojerdi, B. Hallett, M. (2000) Effects of low-frequency transcranial magnetic stimulation on motor excitability and basic motor behavior Clin. Neurophysiology, 111, 1002 1007.
24. Murase, N., Duque, J., Mazzocchio, R. Cohen, L.G. (2004) Influence of interhemispheric interactions on motor function in chronic stroke. Ann. Neurol., 55, 400 409.
25. Nair, D.G., Hutchinson, S., Fregni, F., Alexander, M., Pascual-Leone, A. Schlaug, G. (2007) Imaging correlates of motor recovery from cerebral infarction and their physiological significance in well-recovered patients. Neuroimage, 34, 253 263.
26. Netz, J., Ziemann, U. Hömberg, V. (1995) Hemispheric asymmetry of transcallosal inhibition in man. Exp. Brain Res., 104, 527 533.
27. Nitsche, M.A. Paulus, W. (2000) Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation. J. Physiol., 527, 633 639.
28. Nitsche, M.A. Paulus, W. (2001) Sustained excitability elevations induced by transcranial DC motor cortex stimulation in humans. Neurology, 57, 1899 1901.
29. Nitsche, M.A., Fricke, K., Henschke, U., Schlitterlau, A., Liebetanz, D., Lang, N., Henning, S., Tergau, F. Paulus, W. (2003a) Pharmacological modulation of cortical excitability shifts induced by transcranial DC stimulation. J. Physiol., 553, 293 301.
30. Nitsche, M.A., Schauenburg, A., Lang, N., Liebetanz, D., Exner, C., Paulus, W. Tergau, F. (2003b) Facilitation of implicit motor learning by weak transcranial direct current stimulation of the primary motor cortex in the human. J. Cog. Neurosci., 15, 619 626.
31. Ohn, S.H., Park, C.-I., Yoo, W.-K., Ko, M.-H., Choi, K.P., Kim, G.-M., Lee, Y.T. Kim, Y.-H. (2007) Time-dependent effect of transcranial direct current stimulation on the enhancement of working memory. Neuroreport, 19, 43 47.
32. Okamoto, M., Dan, H., Sakamoto, K., Takeo, K., Shimizu, K., Kohno, S., Oda, I., Isobe, S., Suzuki, T., Kohyama, K. Dan, I. (2004) Three-dimensional probabilistic anatomical cranio-cerebral correlation via the international 10-20 system oriented for transcranial functional brain mapping. Neuroimage, 21, 99 111.
33. Oldfield, R.C. (1971) The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia, 9, 97 113.
34. Pal, P.K., Hanajima, R., Gunraj, C.A., Li, J.-Y., Wagle-Shukla, A., Morgante, F. Chen, R. (2005) Effect of low-frequency repetitive transcranial magnetic stimulation on interhemispheric inhibition. J. Neurophysiol., 94, 1668 1675.
35. Robertson, E.M., Press, D.Z. Pascual-Leone, A. (2005) Off-line learning and the primary motor cortex. J. Neurosci., 25, 6372 6378.
36. Rogalewski, A., Breitenstein, C., Nitsche, M.A., Paulus, W. Knecht, S. (2004) Transcranial direct current stimulation disrupts tactile perception. Eur. J. Neurosci., 20, 313 316.
37. Schulze, K., Luders, E. Jancke, L. (2002) Intermanual transfer in a simple motor task. Cortex, 38, 805 815.
38. Siebner, H.R., Lang, N., Rizzo, V., Nitsche, M.A., Paulus, W., Lemon, R.N. Rothwell, J.C. (2004) Preconditioning of low frequency repetitive transcranial magnetic stimulation with transcranial direct current stimulation: evidence for homeostatic plasticity in the human motor cortex. J. Neurosci., 24, 3379 3385.
39. Takeuchi, N., Chuma, T., Matsuo, Y., Watanabe, I. Ikoma, K. (2005) Repetitive transcranial magnetic stimulation of contralesional primary motor cortex improves hand function after stroke. Stroke, 36, 2681 2686.
40. Talelli, P. Rothwell, J. (2006) Does brain stimulation after stroke have a future? Curr. Opin. Neurol., 19, 543 550.
41. Vines, B.W., Nair, D.G. Schlaug, G. (2006a) Contralateral and ipsilateral motor effects after transcranial direct current stimulation. Neuroreport, 17, 671 674.
42. Vines, B.W., Schnider, N. Schlaug, G. (2006b) Testing for causality with tDCS: pitch memory and the left supramarginal gyrus. Neuroreport, 17, 1047 1050.
43. Wahl, M., Lauterbach-Soon, B., Hattingen, E., Ogrezeanu, G., Lanfermann, H. Ziemann, U. (2007) Determining the topography of interhemispheric fibres in the human corpus callosum (CC) between the primary motor cortices with a combined fMRI/DTI-fibretracking procedure. Clin. Neurophysiol., 118, e109 e110.
44. Wassermann, E.M., Wedegaertner, F.R., Ziemann, U., George, M.S. Chen, R. (1998) Crossed reduction of human motor cortex excitability by 1-Hz transcranial magnetic stimulation. Neurosci. Lett., 250, 141 144.
45. Wittenberg, G.F., Bastian, A.J., Dromerick, A.W., Thach, W.T. Powers, W.J. (2000) Mirror movements complicate interpretation of cerebral activation changes during recovery from subcortical infarction. Neuralrehabil. Neural. Repair, 14, 213 221.