Does brain stimulation after stroke have a future?

Current Opinion in Neurology

Volumn 19, Issue 6, 2006, Pages 543-550

  Talelli, Penelope ^a   Rothwell, John ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Cortical stimulation; Poststroke plasticity; Repetitive transcranial magnetic stimulation; Stroke rehabilitation; Transcranial direct current stimulation

Indexed keywords

APHASIA; BRAIN CORTEX; BRAIN DEPTH STIMULATION; BRAIN FUNCTION; DIRECT CURRENT; ELECTROSTIMULATION; HEMISPHERE; HUMAN; MOTOR DYSFUNCTION; NERVE CELL PLASTICITY; REVIEW; STROKE; TRANSCRANIAL MAGNETIC STIMULATION; VISUAL DEPRIVATION;

APHASIA; CEREBRAL CORTEX; CEREBROVASCULAR ACCIDENT; ELECTRIC STIMULATION THERAPY; HUMANS; PARESIS; PERCEPTUAL DISORDERS; RECOVERY OF FUNCTION; TRANSCRANIAL MAGNETIC STIMULATION; TREATMENT OUTCOME;

EID: 33751023605     PISSN: 13507540     EISSN: None     Source Type: Journal    
DOI: 10.1097/WCO.0b013e32801080d1     Document Type: Review

References (32)

1. Talelli P, Greenwood RJ, Rothwell JC. Arm function after stroke: neurophysiological correlates and recovery mechanisms assessed by transcranial magnetic stimulation. Clin Neurophysiol 2006; 117:1641-1659. This is a detailed account of the current research using TMS to quantify damage and explore recovery mechanisms after motor stroke.
2. Zhang W, Linden DJ. The other side of the engram: experience-driven changes in neuronal intrinsic excitability. Nat Rev Neurosci 2003; 4:885-900.
3. Nudo RJ, Wise BM, SiFuentes F, et al. Neural substrates for the effects of rehabilitative training on motor recovery after ischemic infarct. Science 1996; 272:1791-1794.
4. Ward NS, Cohen LG. Mechanisms underlying recovery of motor function after stroke. Arch Neurol 2004; 61:1844-1848.
5. Gerloff C, Bushara K, Sailer A, et al. Multimodal imaging of brain reorganization in motor areas of the contralesional hemisphere of well recovered patients after capsular stroke. Brain 2006; 129:791-808. This sophisticated study employs a multimodal design to explore potential differences in the role of the contralesional motor areas in stroke patients with different levels of recovery.
6. Tsubokawa T, Katayama Y, Yamamoto T, et al. Chronic motor cortex stimulation in patients with thalamic pain. J Neurosurg 1993; 78:393-401.
7. Brown JA, Pilitsis JG. Motor cortex stimulation. Pain Med 2006; 7 (Suppl 1):S140-S145. This is a detailed review of the clinical applications of epidural electrical stimulation and the mechanisms underlying its effect.
8. Nitsche MA, Paulus W. Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation. J Physiol 2000; 527 (Pt 3): 633-639.
9. Nitsche MA, Liebetanz D, Lang N, et al. Safety criteria for transcranial direct current stimulation (tDCS) in humans. Clin Neurophysiol 2003; 114:2220-2222.
10. Rothwell JC. Techniques and mechanisms of action of transcranial stimulation of the human motor cortex. J Neurosci Methods 1997; 74:113-122.
11. Chen R, Gerloff C, Classen J, et al. Safety of different inter-train intervals for repetitive transcranial magnetic stimulation and recommendations for safe ranges of stimulation parameters. Electroencephalogr Clin Neurophysiol 1997; 105:415-421.
12. Fregni F, Boggio PS, Mansur CG, et al. Transcranial direct current stimulation of the unaffected hemisphere in stroke patients. Neuroreport 2005; 16:1551-1555. This is a well-designed single-session study which provides a direct comparison between the two ways to use stimulation in chronic stroke, i.e. excitation of the stroke hemisphere and suppression of the nonstroke hemisphere.
13. Hummel F, Celnik P, Giraux P, et al. Effects of noninvasive cortical stimulation on skilled motor function in chronic stroke. Brain 2005; 128:490-499. This single-session study additionally employs TMS measures to explore the mechanisms underlying the behavioural effects of TDCS in stroke.
14. Mansur CG, Fregni F, Boggio PS, et al. A sham stimulation-controlled trial of rTMS of the unaffected hemisphere in stroke patients. Neurology 2005; 64:1802-1804.
15. Takeuchi N, Chuma T, Matsuo Y, et al. Repetitive transcranial magnetic stimulation of contralesional primary motor cortex improves hand function after stroke. Stroke 2005; 36:2681-2686. This single-session study employs TMS to provide electrophysiological evidence of the effects that suppressing rTMS of the nonstroke hemisphere has on the stroke hemisphere.
16. Kim YH, You SH, Ko MH, et al. Repetitive transcranial magnetic stimulation-induced corticomotor excitability and associated motor skill acquisition in chronic stroke. Stroke 2006; 37:1471-1476.
17. Brown JA, Lutsep HL, Weinand M, et al. Motor cortex stimulation for the enhancement of recovery from stroke: a prospective, multicenter safety study. Neurosurgery 2006; 58:464-473.
18. Bezard E, Boraud T, Nguyen JP, et al. Cortical stimulation and epileptic seizure: a study of the potential risk in primates. Neurosurgery 1999; 45:346-350.
19. Parker VM, Wade DT, Langton HR. Loss of arm function after stroke: measurement, frequency, and recovery. Int Rehabil Med 1986; 8:69-73.
20. Brighina F, Bisiach E, Oliveri M, et al. 1 Hz repetitive transcranial magnetic stimulation of the unaffected hemisphere ameliorates contralesional visuospatial neglect in humans. Neurosci Lett 2003; 336:131-133.
21. Naeser MA, Martin PI, Nicholas M, et al. Improved picture naming in chronic aphasia after TMS to part of right Broca's area: an open-protocol study. Brain Lang 2005; 93:95-105.
22. Shindo K, Sugiyama K, Huabao L, et al. Long-term effect of low-frequency repetitive transcranialmagnetic stimulation over the unaffected posterior parietal cortex in patients with unilateral spatial neglect. J Rehabil Med 2006;38:65-67.
23. Winhuisen L, Thiel A, Schumacher B, et al. Role of the contralateral inferior frontal gyrus in recovery of language function in poststroke aphasia: a combined repetitive transcranial magnetic stimulation and positron emission tomography study. Stroke 2005; 36:1759-1763.
24. Khedr EM, Ahmed MA, Fathy N, et al. Therapeutic trial of repetitive transcranial magnetic stimulation after acute ischemic stroke. Neurology 2005; 65:466-468.
25. Werhahn KJ, Conforto AB, Kadom N, et al. Contribution of the ipsilateral motor cortex to recovery after chronic stroke. Ann Neurol 2003; 54:464-472.
26. Lotze M, Markert J, Sauseng P, et al. The role of multiple contralesional motor areas for complex hand movements after internal capsular lesion. J Neurosci 2006; 26:6096-6102. This is an interesting study that combines TMS-induced virtual lesions and functional magnetic resonance imaging activation to show that the role of the contralesional hemisphere in poststroke recovery may depend on the difficulty of the task performed with the paretic hands.
27. Gerloff C, Corwell B, Chen R, et al. The role of the human motor cortex in the control of complex and simple finger movement sequences. Brain 1998; 121(Pt 9):1695-1709.
28. Baumer T, Lange R, Liepert J, et al. Repeated premotor rTMS leads to cumulative plastic changes of motor cortex excitability in humans. Neuroimage 2003; 20:550-560.
29. Uy J, Ridding MC, Hillier S, et al. Does induction of plastic change in motor cortex improve leg function after stroke? Neurology 2003; 61:982-984.
30. Martin PI, Naeser MA, Theoret H, et al. Transcranial magnetic stimulation as a complementary treatment for aphasia. Semin Speech Lang 2004; 25:181-191.
31. Silverman IE, Restrepo L, Mathews GC. Poststroke seizures. Arch Neurol 2002; 59:195-201.
32. Ziemann U, Ilic TV, Pauli C, et al. Learning modifies subsequent induction of long-term potentiation-like and long-term depression-like plasticity in human motor cortex. J Neurosci 2004; 24:1666-1672.