The 2005 meta-analysis of homeopathy: the importance of post-publication data

Homeopathy

Volumn 97, Issue 4, 2008, Pages 169-177

  Rutten, A L B ^a   Stolper, C F ^a  

^a NONE   (Netherlands)

Author keywords

adverse effects; comparative analysis; cut off value; homeopathy; meta analysis; quality bias; selection bias

Indexed keywords

ARTICLE; CLINICAL TRIAL; DATA ANALYSIS; HOMEOPATHY; HYPOTHESIS; MUSCLE FATIGUE; OUTCOME ASSESSMENT; PUBLICATION; RUNNING; SENSITIVITY ANALYSIS; SYSTEMATIC ERROR; THERAPY EFFECT; TREATMENT INDICATION;

HISTORY, 21ST CENTURY; HOMEOPATHY; HUMANS; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

EID: 53949087578     PISSN: 14754916     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.homp.2008.09.008     Document Type: Article

References (61)

1. Kleijnen J., Knipschild P., and ter Riet G. Clinical trials of homeopathy. BMJ 302 (1991) 316-323
2. Linde K., Clausius N., Ramirez G., et al. Are the clinical effects of homeopathy placebo effects? A meta-analysis of placebo-controlled trials. Lancet 350 (1997) 834-843
3. Cucherat M., Haugh M., Gooch M., and Boissel J. Evidence of clinical efficacy of homeopathy - A meta-analysis of clinical trials. Eur J Clin Pharmacol 56 (2000) 27-33
4. Morrison B., Lilford R.J., and Ernst E. Methodological rigour and results of clinical trials of homeopathic medicines. Perfusion 13 (2000) 132-138
5. Ernst E. A systematic review of systematic reviews of homeopathy. J Clin Pharmacol 54 (2002) 577-582
6. Ezzo J., Bausell B., Moerman D.E., Berman B., and Hadhazy V. Reviewing the reviews. How strong is the evidence? How clear are the conclusions?. Int J Technol Assess Health Care 17 4 (2001 Fall) 457-466
7. Vandenbroucke J.P. Medical journals and the shaping of medical knowledge. Lancet 352 (1998) 2001-2006
8. Sterne J.A.C., Egger M., and Smith G.D. Investigating and dealing with publication and other biases in meta-analysis. BMJ 323 (2001) 101-105
9. Shang A., Huwiler-Müntener K., Nartey L., et al. Are the clinical effects of homeopathy placebo effects? Comparative study of placebo-controlled trials of homeopathy and allopathy. Lancet 366 (2005) 726-732
10. Vandenbroucke J.P. Homeopathy and the growth of truth. Lancet 366 (2005) 691-692
11. In: Higgins J.P.T., and Green S. (Eds). Cochrane Handbook for Systematic Reviews of Interventions 4.2.5. The Cochrane Library Issue 3 (2005) Chichester, UK: John Wiley & Sons, Ltd [updated May 2005]
12. Jonas W.B., Kaptchuk T.J., and Linde K. A critical overview of homeopathy. Ann Intern Med 138 (2003) 393-399
13. Egger M., Smith G.D., and Altman D.G. Systematic reviews in health care: meta-analysis in context. 2nd edition (2001), BMJ Books
14. Boden W.E. Meta-analysis in clinical trials reporting: has a tool become a weapon?. Am J Cardiol 69 (1992) 681-686
15. Walach H., Jonas W., and Lewith G. Letter to the editor. Lancet 366 (2005) 2081
16. Linde K., and Jonas W.B. Letter to the editor. Lancet 366 (2005) 2081-2082
17. Fisher P., Berman B., Davidson J., Reilly D., Thompson T., et al. Letter to the editor. Lancet 366 (2005) 2082-2083
18. Lüdtke R., and Rutten A.L.B. The conclusions on the effectiveness of homeopathy highly depend on the set of analysed trials. J Clin Epid (2008) 10.1016/j.jclinepi.2008.06.015
19. Gade J., and Thorn P. Paraghurt for patients with irritable bowel syndrome: a controlled clinical investigation from general practice. Scand J Prim Health Care 7 (1989) 23-26
20. Humphrey R.G., Bartfield M.C., Carlan S.J., O'Brien W.F., O'Leary T.D., and Triana T. Sulindac to prevent recurrent preterm labor: a randomized controlled trial. Obstet Gynecol 98 (2001) 555-562
21. Chan A.W., Hjobartsson A., Haahr M.T., Gotzsche P.C., and Altman D.G. Emperical evidence for selective reporting of outcomes in randomized trials: comparison of protocols to published articles. JAMA 291 (2004) 2457-2465
22. Wiesenauer M., and Gaus W. Wirksamkeitsnachweis eines Homöopathikums bei chronischer Polyarthritis. Eine randomisierte Doppelblindstudie bei niedergelassenen Ärzten. Aktuelle Rheumatologie 16 (1991) 1-9
23. Schmidt J.M., and Ostermayr B. Does a homeopathic ultramolecular dilution of Thyroidinum 30CH affect the decrease of body weight reduction in fasting patients? - A randomised Placebo-controlled double-blind trial. Homeopathy 91 4 (2002) 197-206
24. Enzi G., Crepaldi G., Inelmen E.M., Bruni R., and Baggio B. Efficacy and safety of dexfenfluramine in obese patients: amulticenter study. Clin Neuropharmacology 12 (1995) S173-S178
25. Available from:.
26. Louviere R.L., and Upton R.T. Evaluation of Deladumone OB in the suppression of postpartum lactation. Am J Obstet Gynecol 121 (1975) 641-642
27. Lacey P.H., Dodd G.D., and Shannon D.J. A double blind, placebo controlled study of piroxicam in the management of acute muscoloskeletal disorders. Eur J Rheum Inflam 7 (1984) 95-104
28. Available from:.
29. EMEA. Press release (25 June 2007), European Medicines Agency Recommends Restricted Use for Piroxicam, London
30. Grio R., Cellura A., Geranio R., Porpiglia M., and Piacentino R. Efficacia clinica del tamoxifene nel trattamento della mastodynia premenstruale. Min Ginecol 50 (1998) 101-103
31. de Lange-de Klerk E.S.M. Effects of homeopathic medicines on children with recurrent upper respiratory tract infections. BMJ 309 (1994) 1329-1332
32. Reilly D.T., Taylor M.A., McSharry C., and Aitchison T. Is homeopathy a placebo response? Controlled trial of homeopathic potency with pollen in hay fever as model. Lancet (1986) 881-886
33. Hofmeyr G.J., Picconi V., and Blauhof P. Postpartum homeopathic Arnica montana: a potency-finding pilot study. Br J Clin Pract 44 (1990) 619-621
34. Reilly D., Taylor M.A., Beattie N.G., et al. Is evidence for homeopathy reproducible?. Lancet 344 (1994) 1601-1606
35. Schulz K.F., Chalmers I., Hayes R.J., and Altman D. Emperical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials. JAMA 273 (1995) 408-412
36. Rottey E.E.D., Verleye G.B., and Liagre R.L.P. Het effect van een homeopathische bereiding van micro-organismen bij de preventie von griepsymtomen - Een gerandomiseerd dubbel-blind onderzoek in de huisartspraktijk. Tijdschr Integ Geneeskunde 11 (1995) 54-58
37. Vickers A.J., Fisher P., Wyllie S.E., and Rees R. Homeopathic Arnica 30X Is Ineffective for Muscle Soreness After Long-Distance Running - A randomized, double-blind, Placebo-controlled trial. Clin J Pain 14 3 (1998) 227-231
38. Papp R., Schuback G., Beck E., et al. Oscillococcinum in patients with influenza-like syndroms: A placebo controlled double-blind evaluation. Brit Homeopath J 87 2 (1998) 69-76
39. Labrecque M., Audet D., Latulippe L., and Drouin J. Homeopathic treatment of plantar warts. Can Med Assoc J 146 10 (1992) 1749-1753
40. Jacobs J., Jiménez L.M., Malthouse S., et al. Homeopathic Treatment of Acute Childhood Diarrhea - Results from a Clinical Trial in Nepal. J Alternat Complement Med 6 2 (2000) 131-139
41. Weiser M., and Clasen B.P.E. Randomisierte plazebokontrollierte Doppelblindstudie zur Untersuchung der klinischen Wirksamkeit der homöopathischen Euphorbium compositum-Nasentropfen S bei chronischer Sinusitis. Forsch Komplementarmed 1 (1994) 251-259
42. Walach H., Haeusler W., Lowes T., et al. Classical homeopathic treatment of chronic headaches. Cephalalgia 17 (1997) 119-126
43. Jacobs J., Jiménez L.M., Gloyd S.S., Gale J.L., and Crothers D. Treatment of Acute Childhood Diarrhea With Homoeopathic Medicine: A Randomized Clinical Trial in Nicaragua. Pediatrics 93 5 (1994) 719-725
44. Jacobs J., Springer D.A., and Crothers D. Homeopathic treatment of acute otitis media in children: a preliminary randomized placebo- controlled trial. Pediatr Infect Dis J (2001) 177-183
45. Hart O., Mullee M.A., Lewith G., and Miller J. Double-blind, placebo-controlled, randomized clinical trial of homoeopathic arnica C30 for pain and infection after total abdominal hysterectomy. J R Soc Med 90 (1997) 73-78
46. Wiesenauer M., Häussler S., and Gaus W. Pollinosis-Therapie mit Galphimia glauca. MMW Fortschr Med 101 17 (1983) 811-814
47. Zell J., Connert W.D., Mau J., and Feuerstake G. Behandlung von akuten Sprunggelenksdistorsionen - Doppelblindstudie zum Wirksamkeitsnachweis eines homöopathischen Salbenpräparats. MMW Fortschr Med 106 5 (1988) 96-100
48. Böhmer D., and Ambrus P. Behandlung von Sportverletzungen mit Traumeel-Salbe - Kontrollierte Doppelblindstudie. Biol Medizin 21 4 (1992) 260-268
49. Vickers A.J., Fisher P., Smith C., Wyllie S.E., and Lewith G.T. Homoeopathy for delayed onset muscle soreness - A randomised double blind placebo controlled trial. Brit J Sports Med 31 (1997) 304-307
50. Jawara N., Lewith G.T., Vickers A., Mullee M.A., and Smith C. Homoeopathic Arnica and Rhus toxicodendron for delayed onset muscle soreness - A pilot for a randomized, double-blind, placebo-controlled trial. Brit Hom J 86 1 (1997) 10-15
51. Chapman E.H., Weintraub R.J., and Milburn M.A. Homeopathic Treatment of Mild Traumatic Brain Injury - A Randomised, Double-Blind, Placebo- Controlled Clinical Trial. J Head Trauma Rehabil 14 (1999) 521-542
52. Tveiten D., Bruset S., Borchgrevink C.F., and Norseth J. Effects of the homeopathic remedy Arnica D30 on marathon runners: A randomized, double-blind study during the 1995 Oslo Marathon. Complement Ther Med 6 2 (1998) 71-74
53. Stevinson C., Devaraj V.S., and Fountain-Barber A. homeopathic arnica for prevention of pain and bruising: randomized placebo-controlled trial in hand surgery. J R Soc Med 96 (2003) 60-65
54. Lepaisant C. Essai thérapeutique en homéopathie: traitement des tensions mammaires et mastodynies du syndrome prémenstruel. Rev Fr Gynécol Obstét 90 2 (1995) 94-97
55. Chapman E.H., Angelica J., Spitalny G., and Strauss M. Results of a study of the homoeopathic treatment of PMS. J Am Inst Hom 87 (1994) 14-21
56. Kaplan M.A., Prior M.J., McKonly K.I., Du Pont H.L., Temple A.R., and Nelson E.B. A multicenter randomized controlled trial of a liquid loperamide product versus placebo in the treatment of acute diarrhea in children. Clin Pediatr 38 (1999) 579-591
57. Nicholson K.G., Aoki F.Y., Osterhaus A.D.M.E., et al. Efficacy and safety of oseltamivir in treatment of acute influenza: a randomised controlled trial. Lancet 355 (2000) 1845-1850
58. de Flora S., Grassi C., and Carati L. Attenuation of influenza-like symptomatology and improvement of cell-mediated immunity with long-term N-acetylcysteine treatment. Eur Respir J 10 (1997) 1535-1541
59. Egger M., Smith G.D., and Philips A.N. Meta-analysis: principles and procedures. BMJ 315 (1997) 1533-1537
60. Shang A., Huwiler-Muntener K., Martey L., Jüni P., Dörig S., Sterne J.A.C., et al. Author's reply. Lancet 366 (2005) 2083-2085
61. Vergouwen M.D., de Haan R.J., Vermeulen M., and Roos Y.B. Statin treatment of hemorrhagic stroke in patients with a history of cerebrovascular disease. Stroke 39 (2008) 497-502