L-methionine toxicity in freshly isolated mouse hepatocytes is gender-dependent and mediated in part by transamination

Journal of Pharmacology and Experimental Therapeutics

Volumn 326, Issue 3, 2008, Pages 809-817

  Dever, Joseph T ^a   Elfarra, Adnan A ^a,b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 DEAZAADENOSINE; 3 METHYLTHIOPROPIONIC ACID; ADENOSYLHOMOCYSTEINASE; AMINOOXYACETIC ACID; GLUTATHIONE; GLUTATHIONE DISULFIDE; HOMOCYSTEINE THIOLACTONE; LACTATE DEHYDROGENASE; METHIONINE; PROPIONIC ACID DERIVATIVE; TRYPAN BLUE; UNCLASSIFIED DRUG; OXOACID;

AMINO ACID SYNTHESIS; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL VIABILITY; CHOLESTASIS; CONTROLLED STUDY; CYTOTOXICITY; INCUBATION TIME; LIPID PEROXIDATION; LIVER CELL CULTURE; LIVER TOXICITY; METABOLITE; METHYLATION; MOUSE; NONHUMAN; PARENTERAL NUTRITION; PRIORITY JOURNAL; SEX DIFFERENCE; TRANSAMINATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CELL SURVIVAL; COMPARATIVE STUDY; DRUG EFFECTS; FEMALE; LIVER CELL; MALE; METABOLISM; PHYSIOLOGY; SEXUAL DEVELOPMENT; SIGNAL TRANSDUCTION; TOXICITY;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; FEMALE; GLUTATHIONE; HEPATOCYTES; KETO ACIDS; MALE; METHIONINE; MICE; SEX CHARACTERISTICS; SIGNAL TRANSDUCTION;

EID: 53849085509     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.108.141044     Document Type: Article

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