Antibodies as predictors of complex autoimmune diseases and cancer

International Journal of Immunopathology and Pharmacology

Volumn 21, Issue 3, 2008, Pages 553-566

  Vojdani, Aristo ^a,b  

^a Immunosciences Laboratories Inc   (United States)

^b NONE   (United States)

Author keywords

Autoimmune diseases; Cancer; ELISAIntroduction; Environmental triggers; Neuroimmune disorders; Polyreactive antibodies; Predictive antibodies

Indexed keywords

AUTOANTIBODY; PEPTIDE; TUMOR ANTIGEN;

ANTIBODY PRODUCTION; ANTIGEN ANTIBODY REACTION; ANTIGEN DETECTION; ANTIGEN SPECIFICITY; ARTICLE; AUTISM; AUTOIMMUNE DISEASE; BORRELIA INFECTION; BREAST CANCER; CELLULAR IMMUNITY; CHRONIC OBSTRUCTIVE LUNG DISEASE; COLON CANCER; CONTROLLED STUDY; EARLY DIAGNOSIS; ENZYME IMMUNOASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION; HUMAN; LIVER DISEASE; LUNG DISEASE; MAJOR CLINICAL STUDY; NEOPLASM; NEURAL TUBE DEFECT; NEUROLOGIC DISEASE; PREGNANCY COMPLICATION; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL; PROGNOSIS; PROSTATE CANCER; SOMATIC HYPERMUTATION; TISSUE SPECIFICITY;

EID: 53749104937     PISSN: 03946320     EISSN: None     Source Type: Journal    
DOI: 10.1177/039463200802100308     Document Type: Article

References (40)

1. Steinman L. Multiple sclerosis: a coordinated immunological attack against myelin in the nervous system. Cell 1996; 85:299-302.
2. Raine CS, Cannella B, Hauser SL, Genain CP. Demyelination in primate autoimmune encephalomyelitis and acute multiple sclerosis lesions: a case for antigen-specific antibody mediation. Ann Neurol 1999; 46:144-60.
3. Wilson, NJ, Boniface K, Chan JR, McKenzie BS, Blumenschein WM, Mattson JD, Basham B, Smith K, Chen T, Morel F, Lecron JC, Kastelein RA, Cua DJ, McClanahan TK, Bowman EP, de Waal Malefyt R. Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nat Immunol 2007; 8:950-7.
4. Stone LA, Smith ME, Albert PS, Bash CN, Maloni H, Frank JA, McFarland HF. Blood-brain barrier disruption on contrast-enhanced MRI in patients with mild relapsing-remitting multiple sclerosis: relationship to course, gender, and age. Neurol 1995;45: 1122-6.
5. Kim JV, Dustin ML. Innate response to focal necrotic injury onside the blood-brain barrier. J Immunol 2006; 177:5269-77.
6. Phares TW, Fabis MJ, Brimer CM, Kean RB, Hooper DC. Aperoxynitrite-dependent pathway is responsible for blood-brain barrier permeability changes during a central nervous system inflammatory response: TNF-α is neither necessary or sufficient. J Immunol 2007; 178:7334-7343.
7. H 17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation. Nature Med 2007; 13:1173-6.
8. Ahmed S, Tsukahara S, Tin-Tin-Win-Shwe, Yamamoto S, Kunugita N, Arashidani K, Fujimaki H. Effects of low-level formaldehyde exposure on synaptic plasticity-related gene expression in hippocampus of immunized mice. J Neuroimmunol 2007; 186:101-11.
9. Missmer SA, Suarez L, Felkner M, et al. Exposure to fumonisins and the occurrence of neural tube defects along the Texas-Mexico border. Environ Health Perspect 2006; 114:237-41
10. Rothenberg SP, da Costa MP, Sequeira JM, et al. Autoantibodies against folate receptors in women with a pregnancy complicated by a neural-tube defect. New Engl J Med 2004; 350:134-42
11. Vojdani A, Hebroni F, Raphael Y, et al. Novel diagnosis of Lyme disease: potential for CAM intervention. eCAM published online on 15 October 2007, doi:10.1093/ecam/nem138
12. Vojdani A, Pangborn JB, Vojdani E, Cooper EL. Infections, toxic chemicals and dietary peptides binding to lymphocyte receptors and tissue enzymes are major instigators of autoimmunity in autism. Int J Immunopathol Pharmacol 2003; 16(3):189-99.
13. Leung PSC, Park O, Tsuneyama K, et al. Induction of primary biliary cirrhosis in guinea pigs following chemical xenobiotic immunization. J Immunol 2007; 179:2651-7
14. Lee S, Goswami S, Gurdo A, et al. Antielastin autoimmunity in tobacco smoking-induced emphysema. Nature Med 2007; 13:567-9
15. Keogh E, Fikes J, Southwood S, Celis E, Chestnut R, Sette A. Identification of new epitopes from four different tumor-associated antigens: recognition of naturally processed epitopes correlates with HLA-A*0201-binding affinity. J Immunol 2001; 167:787-96.
16. Allen SD, Garrett JT, Rawale SV, et al. Peptide vaccines of the HER-2/ neu dimerization loop are effective in inhibiting mammary tumor growth in vivo. J Immunol 2002; 179:472-82
17. Kotlan B, Simsa P, Teillaud J-L, et al. Novel ganglioside antigen identified by B cells in human medullary breast carcinomas: the proof of principle concerning the tumor-infiltrating B lymphocytes. J Immunol 2005; 175:2278-85
18. Penna G, Amuchastegui S, Cossetti C, et al. Spontaneous and prostatic steroid binding protein peptide-induced autoimmune prostatitis in the nonobese diabetic mouse. J Immunol 2007; 179: 1559-67
19. Siegel S, Wagner A, Friedrichs B, et al. Identification of HLA-A*0201-Presented T cell epitopes derived from the oncofetal antigen-immature laminin receptor protein in patients with hematological malignancies. J Immunol 2006; 176:6935-44
20. Soussi T. P53 antibodies in the sera of patients with various types of cancer: a review. Cancer Res 2000; 60:1777-88
21. Nilsson BO, Carlsson L, Larsson A, Ronquist G. Autoantibodies to prostasomes as new markers for prostate cancer. Ups J Med Sci 2001; 106:43-9
22. Soares MM, Mehta V, Fin OJ. Three different vaccines based on the 140-amino acid MUC1 peptide with seven tandemly repeated tumor-specific epitopes elicit distinct immune effector mechanisms in wild-type versus MUC1-transgenic mice with different potential for tumor rejection. J Immunol 2001; 166:6555-63
23. Wang X, Yu J, Sreekumar A, Varambally S, Shen R, Giacherio D, Mehra R, Montie JE, Pienta KJ, Sanda MG, Kantoff PW, Rubin MA, Wei JT, Ghosh D, Chinnaiyan AM. Autoantibody signatures in prostate cancer. N Engl J Med 2005; 353:1224-35.
24. Hsu HC, Wu Y, Yang P, et al. Overexpression of activation-induced cytidine deaminase in B cells is associated with production of highly pathogenic autoantibodies. J Immunol 2007; 178:5357-65
25. Vojdani A, Vojdani E, Cooper EL. Antibodies to myelin basic protein, myelin oligodendrocytes peptides, α-β-crystallin, lymphocyte activation and cytokine production in patients with multiple sclerosis. J Internal Med 2003; 254:363-374.
26. Berger T, Rubner P, Schnautzer F, et al. Antimyclin antibodies as a predictor of clinically definite multiple sclerosis after first demyelinating event. N Engl J Med 2003; 349:139-45
27. Challoner PB, Smith KT, Parker JD, et al. Plaque-associated expression of human herpesvirus 6 in multiple sclerosis. Proc Natl Acad Sci USA 1995; 92:7440-4
28. Tsunoda I, Libbey JE, Fujinami RS. Sequential polymicrobial infections lead to CNS inflammatory disease: possible involvement of bystander activation in heterologous immunity. J Neuroimmunol 2007; 188:22-33
29. Paterson G, Wilson G, Kennedy PGE, Willison HJ. Analysis of anti-GM1 ganglioside IgM antibodies cloned from motor neuropathy patients demonstrate diverse V region gene usage with extensive somatic mutation. J Immunol 1995; 155:3049-59
30. Peggy C, Godschalk R, Kujif ML, et al. Structural characterization of Campylobacter jejuni lipooligosaccharide outer cores associated with Guillain-Barre and Miller Fisher syndromes. Infec Immun. 2007; 75:1245-54
31. Rogers SW, Twyman RE, Gahring LC. The role of autoimmunity to glutamate receptors in neurological disease. Mol Med Today 1996;2:76-81
32. Rakhit R, Robertson J, Velde CV, et al. An immunological epitope selective for pathological monomer - misfolded SOD1 in ALS. Nature Med 2007; 13:754-9
33. Mell LK, Davis RL, Owens D. Association between streptococcal infection and obsessive-compulsive. disorder, Tourette's syndrome, and tic disorder. Pediatr 2005; 116:56-60
34. Kirvan CA, Cox CJ, Swedo SE, Cunningham MW. Tubulin is a neuronal target of autoantibodies in Sydenham's chorea. J Immunol 2007; 178:7412-21
35. Centers for Disease Control and Prevention. Recommendation for test performance and interpretation from the Second National Conference on Serologic Diagnosis of Lyme Disease. MMWR, Morb Mortal Wkly Rep 1995; 44:590-591.
36. Engstrom SM, Shoop E, Johnson RC. Immunoblot interpretation criteria for serodiagnosis of early Lyme disease. J Clin M1 crobiol 1995; 33:419-27
37. Sequin P, Allard A, Cartier A, Malo JL. Prevalence of occupational asthma in spray painters exposed to several types of isocyanates. J Occup Med 1987; 29: 340
38. Notkins AL. New Predictor of diseases. Sci Am 2007; 296:72-79.
39. Kuhle J, Pohl C, Mehling M, et al. Lack of association between antimyelin antibodies and progression to multiple sclerosis. N Engl J Med 2007; 356:371-8.
40. Peterson LK, Tsunoda I, Masaki T, Fujinami RS. Polyreactive myelin oligodendrocyte glycoprotein antibodies: implications for systemic autoimmunity in progressive experimental autoimmune encephalomyelitis. J Neuroimmunol 2007; 183:69-80.