A single dose of anti-D immunoglobulin raises platelet count as efficiently as intravenous immunoglobulin in newly diagnosed immune thrombocytopenic purpura in korean children

Journal of Pediatric Hematology/Oncology

Volumn 30, Issue 8, 2008, Pages 598-601

  Son, Dong Woo ^a   Jeon, In Sang ^a   Yang, Sung Wan ^a   Cho, Sang Hee ^a  

^a Gachon University   (South Korea)

Author keywords

Anti D; Immune thrombocytopenic purpura; Immunoglobulin

Indexed keywords

GLOBULIN S; HEMOGLOBIN; IMMUNOGLOBULIN; RHESUS D ANTIBODY; UNCLASSIFIED DRUG;

ARTICLE; CHILD; CHILL; CLINICAL EVALUATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG FEVER; DRUG INDUCED HEADACHE; FEMALE; FEVER; HEADACHE; HUMAN; IDIOPATHIC THROMBOCYTOPENIC PURPURA; KOREA; MAJOR CLINICAL STUDY; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; PROSPECTIVE STUDY; SINGLE DRUG DOSE; THROMBOCYTE COUNT; TREATMENT RESPONSE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; RANDOMIZED CONTROLLED TRIAL; THROMBOCYTE; THROMBOCYTOPENIC PURPURA;

BLOOD PLATELETS; CHILD, PRESCHOOL; FEMALE; HEMOGLOBINS; HUMANS; IMMUNOGLOBULINS, INTRAVENOUS; KOREA; MALE; PLATELET COUNT; PURPURA, THROMBOCYTOPENIC; RHO(D) IMMUNE GLOBULIN;

EID: 53749101830     PISSN: 10774114     EISSN: 15363678     Source Type: Journal    
DOI: 10.1097/MPH.0b013e31817541ba     Document Type: Article

References (17)

1. Kühne T, Imbach P, Bolton-Maggs PHB, et al; for the Intercontinental Childhood ITP Study Group. Newly diagnosed idiopathic thrombocytopenic purpura in childhood: an observational study. Lancet. 2001;358:2122-2125.
2. de Alarcon PA. Immune or idiopathic thrombocytopenic purpura (ITP) in childhood: what are the risks and who should be treated? J Pediatr. 2003;143:287-289.
3. George JN, Woolf SH, Raskob GE, et al. Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for the American Society of Hematology. Blood. 1996;88:3-40.
4. Vesely SK, Buchanan GR, Adix L, et al. Self-reported initial management of childhood idiopathic thrombocytopenic purpura: results of a survey of members of the American Society of Pediatric Hematology/Oncology, 2001. J Pediatr Hematol Oncol. 2003;25: 130-133.
5. Imbach P, Barandun S, d'Apuzzo V, et al. High-dose intravenous gammaglobulin for idiopathic thrombocytopenic purpura in childhood. Lancet. 1981;1:1228-1231.
6. Benesch M, Kerbl R, Lackner H, et al. Low-dose versus high-dose immunoglobulin for primary treatment of acute immune thrombocytopenic purpura in children: results of a prospective, randomized single-center trial. J Pediatr Hematol Oncol. 2003;25:797-800.
7. Warrier I, Bussel JB, Valdez L, et al. Safety and efficacy of low-dose intravenous immune globulin (IVIG) treatment for infants and children with immune thrombocytopenic purpura. Low-Dose IVIG Study Group. J Pediatr Hematol Oncol. 1997;19:197-201.
8. Blanchette V, Imbach P, Andrew M, et al. Randomized trial of intravenous immunoglobulin G, intravenous anti-D, and oral prednisone in childhood acute immune thrombocytopenic purpura. Lancet. 1994;344:703-707.
9. Tarantino MD, Madden RM, Fennewald DL, et al. Treatment of childhood acute immune thrombocytopenic purpura with anti-D immune globulin or pooled immune globulin. J Pediatr. 1999;134: 21-26.
10. Tarantino MD, Young G, Bertolone SJ, et al. Single dose of anti-D immune globulin at 75 microg/kg is as effective as intravenous immune globulin at rapidly raising the platelet count in newly diagnosed immune thrombocytopenic purpura in children. J Pediatr. 2006;148:489-494.
11. Newman GC, Novoa MV, Fodero EM, et al. A dose of 75 microg/kg/d of i.v. anti-D increases the platelet count more rapidly and for a longer period of time than 50 microg/kg/d in adults with immune thrombocytopenic purpura. Br J Haematol. 2001;112:1076-1078.
12. Sekul EA, Cupler EJ, Dalakas MC. Aseptic meningitis associated with high-dose intravenous immunoglobulin therapy: frequency and risk factors. Ann Intern Med. 1994;121:259-262.
13. Gains AR. Disseminated intravascular coagulation associated with hemoglobinemia or hemoglobinuria following Rh(D) immune globulin intravenous administration for immune thrombocytopenic purpura. Blood. 2005;106:1532-1537.
14. Christopher K, Horkan C, Barb IT, et al. Rapid irreversible encephalopathy associated with anti-D immune globulin treatment for idiopathic thrombocytopenic purpura. Am J Hematol. 2004;77: 299-302.
15. Chun NS, Savani B, Seder RH, et al. Acute renal failure after intravenous anti-D immune globulin in an adult with immune thrombocytopenic purpura. Am J Hematol. 2003;74:276-279.
16. Chapel HM, Spickett GP, Ericson D, et al. The comparison of the efficacy and safety of intravenous versus subcutaneous immunoglobulin replacement therapy. J Clin Immunol. 2000;20:94-100.
17. Song S, Crow AR, Freedman J, et al. Monoclonal IgG can ameliorate immune thrombocytopenic purpura in a murine model of ITP: an alternative to IVIG. Blood. 2003;101:3708-3713.