High-dosage intravenous immunoglobulin-associated macrovacuoles are associated with chronic tubulointerstitial lesion worsening in renal transplant recipients

Clinical Journal of the American Society of Nephrology

Volumn 3, Issue 5, 2008, Pages 1461-1468

  Bollée, Guillaume ^a   Anglicheau, Dany ^a   Loupy, Alexandre ^a   Zuber, Julien ^a   Patey, Natacha ^a   Mac Gregor, Duncan ^a   Martinez, Frank ^a   Mamzer Bruneel, Marie France ^a   Snanudj, Renaud ^a   Thervet, Eric ^a   Legendre, Christophe ^a   Noël, Laure Hélène ^a  

^a HÔPITAL NECKER ENFANTS MALADES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN; IMMUNOSUPPRESSIVE AGENT;

ACUTE KIDNEY FAILURE; ADULT; AGE; ARTICLE; ATROPHY; BIOPSY; CELL VACUOLE; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; FEMALE; FIBROSIS; GLOMERULUS FILTRATION RATE; GRAFT REJECTION; HUMAN; KIDNEY FUNCTION TEST; KIDNEY TRANSPLANTATION; KIDNEY TUBULE; MALE; MIDDLE AGED; PATHOLOGY; PATHOPHYSIOLOGY; RETROSPECTIVE STUDY; TIME;

ADULT; AGE FACTORS; ATROPHY; BIOPSY; FEMALE; FIBROSIS; GLOMERULAR FILTRATION RATE; GRAFT REJECTION; HUMANS; IMMUNOGLOBULINS, INTRAVENOUS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY FAILURE, ACUTE; KIDNEY FUNCTION TESTS; KIDNEY TRANSPLANTATION; KIDNEY TUBULES; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; TIME FACTORS; VACUOLES;

EID: 53749098978     PISSN: 15559041     EISSN: 1555905X     Source Type: Journal    
DOI: 10.2215/CJN.00500108     Document Type: Article

References (23)

1. Kazatchkine MD, Kaveri SV: Immunomodulation of auto-immune and inflammatory diseases with intravenous immune globulin. N Engl J Med 345: 747-755, 2001
2. Looney RJ, Huggins J: Use of intravenous immunoglobulin G (IVIG). Best Pract Res Clin Haematol 19: 3-25, 2006
3. Jordan SC, Pescovitz MD: Presensitization: The problem and its management. Clin J Am Soc Nephrol 1: 421-432, 2006
4. Ibernon M, Gil-Vernet S, Carrera M, Seron D, Moreso F, Bestard O, Cruzado JM, Grinyo JM: Therapy with plasmapheresis and intravenous immunoglobulin for acute humoral rejection in kidney transplantation. Transplant Proc 37: 3743-3745, 2005
5. Lehrich RW, Rocha PN, Reinsmoen N, Greenberg A, Butterly DW, Howell DN, Smith SR: Intravenous immunoglobulin and plasmapheresis in acute humoral rejection: Experience in renal allograft transplantation. Hum Immunol 66: 350-358, 2005
6. Anglicheau D, Loupy A, Suberbielle C, Zuber J, Patey N, Noel LH, Cavalcanti R, Le Quintrec M, Audat F, Mejean A, Martinez F, Mamzer-Bruneel MF, Thervet E, Legendre C: Posttransplant prophylactic intravenous immunoglobulin in kidney transplant patients at high immunological risk: A pilot study. Am J Transplant 7: 1185-1192, 2007
7. Orbach H, Tishler M, Shoenfeld Y: Intravenous immunoglobulin and the kidney: A two-edged sword. Semin Arthritis Rheum 34: 593-601, 2004
8. Vo AA, Cam V, Toyoda M, Puliyanda DP, Lukovsky M, Bunnapradist S, Peng A, Yang K, Jordan SC: Safety and adverse events profiles of intravenous gammaglobulin products used for immunomodulation: A single-center experience. Clin J Am Soc Nephrol 1: 844-852, 2006
9. Levy JB, Pusey CD: Nephrotoxicity of intravenous immunoglobulin. QJM 93: 751-755, 2000
10. Centers for Disease Control and Prevention (CDC): Renal insufficiency and failure associated with immune globulin intravenous therapy - United States, 1985-1998. MMWR Morb Mortal Wkly Rep 24: 518-521, 1999
11. Soares SM, Sethi S: Impairment of renal function after intravenous immunoglobulin. Nephrol Dial Transplant 21: 816-817, 2006
12. Haas M, Sonnenday CJ, Cicone JS, Rabb H, Montgomery RA: Isometric tubular epithelial vacuolization in renal allograft biopsy specimens of patients receiving low-dose intravenous immunoglobulin for a positive crossmatch. Transplantation 78: 549-556, 2004
13. Mihatsch MJ, Thiel G, Basler V, Ryffel B, Landmann J, von Overbeck J, Zollinger HU: Morphological patterns in cyclosporine-treated renal transplant recipients. Transplant Proc 17: 101-116, 1985
14. Randhawa PS, Saad RS, Jordan M, Scantlebury V, Vivas C, Shapiro R: Clinical significance of renal biopsies showing concurrent acute rejection and tacrolimus-associated tubular vacuolization. Transplantation 67: 85-89, 1999
15. Moreau JF, Noel LH, Droz D: Proximal renal tubular vacuolization induced by iodinated contrast media, or so-called "osmotic nephrosis." Invest Radiol 28: 187-190, 1993
16. Tervahartiala P, Kivisaari L, Kivisaari R, Vehmas T, Virtanen I: Structural changes in the renal proximal tubular cells induced by iodinated contrast media. Nephron 76: 96-102, 1997
17. Cittanova ML, Leblanc I, Legendre C, Mouquet C, Riou B, Coriat P: Effect of hydroxyethylstarch in brain-dead kidney donors on renal function in kidney-transplant recipients. Lancet 348: 1620-1622, 1996
18. Cockcroft DW, Gault MH: Prediction of creatinine clearance from serum creatinine. Nephron 16: 31-41, 1976
19. Solez K, Colvin RB, Racusen LC, Sis B, Halloran PF, Birk PE, Campbell PM, Cascalho M, Collins AB, Demetris AJ, Drachenberg CB, Gibson IW, Grimm PC, Haas M, Lerut E, Liapis H, Mannon RB, Marcus PB, Mengel M, Mihatsch MJ, Nankivell BJ, Nickeleit V, Papadimitriou JC, Platt JL, Randhawa P, Roberts I, Salinas-Madriga L, Salomon DR, Seron D, Sheaff M, Weening JJ: Banff '05 Meeting Report: Differential diagnosis of chronic allograft injury and elimination of chronic allograft nephropathy ('CAN'). Am J Transplant 7: 518-526, 2007
20. Dickenmann M, Oettl T, Mihatsch MJ: Osmotic nephrosis: Acute kidney injury with accumulation of proximal tubular lysosomes due to administration of exogenous solutes. Am J Kidney Dis 51: 491-503, 2008
21. Chacko B, John GT, Balakrishnan N, Kirubakaran MG, Jacob CK: Osmotic nephropathy resulting from maltose-based intravenous immunoglobulin therapy. Ren Fail 28: 193-195, 2006
22. Schwartz SL, Johnson CB: Pinocytosis as the cause of sucrose nephrosis. Nephron 8: 246-254, 1971
23. Abraham P, Indirani K, Sugumar E: Effect of cyclophosphamide treatment on selected lysosomal enzymes in the kidney of rats. Exp Toxicol Pathol 59: 143-149, 2007