Subtype-specific suppression of Shiga toxin 2 released from Escherichia coli upon exposure to protein synthesis inhibitors

Journal of Clinical Microbiology

Volumn 46, Issue 9, 2008, Pages 2987-2991

  Pedersen, Malene Gantzhorn ^a   Hansen, Claus ^a,b   Riise, Erik ^b   Persson, Søren ^a   Olsen, Katharina E P ^a  

^a STATENS SERUM INSTITUT   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN SYNTHESIS INHIBITOR; VEROTOXIN 2;

ARTICLE; BACTERIAL STRAIN; CYTOTOXICITY; ESCHERICHIA COLI; HUMAN; HUMAN CELL; IN VITRO STUDY; INCUBATION TIME; INTESTINE INFECTION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; WILD TYPE;

AZITHROMYCIN; CIPROFLOXACIN; ENTEROHEMORRHAGIC ESCHERICHIA COLI; ESCHERICHIA COLI O157; GENTAMICINS; KETOLIDES; MICROBIAL SENSITIVITY TESTS; PROTEIN SYNTHESIS INHIBITORS; SHIGA TOXIN 2;

ESCHERICHIA COLI;

EID: 53649101330     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.00871-08     Document Type: Article

References (22)

1. Aertsen, A., D. Faster, and C. W. Michiels. 2005. Induction of Shiga toxin-converting prophage in Escherichia coli by high hydrostatic pressure. Appl. Environ. Microbiol. 71:1155-1162.
2. Andreoli, S. P., H. Trachtman, D. W. K. Acheson, R. L. Sigler, and T. G. Obrig. 2002. Hemolytic uremic syndrome: epidemiology, pathophysiology, and therapy. Pediatr. Nephrol. 17:293-298.
3. Boerlin, P., S. A. McEwen, F. Boerlin-Petzold, J. B. Wilson, R. P. Johnson, and C. L. Gyles. 1999. Associations between virulence factors of Shiga toxin-producing Escherichia coli and disease in humans. J. Clin. Microbiol. 37:497-503.
4. Eklund, M., K. Leino, and A. Siitonen. 2002. Clinical Escherichia coli strains carrying stx genes: stx variants and stx-positive virulence profiles. J. Clin. Microbiol. 40:4585-4593.
5. Ethelberg, S., K. E. Olsen, F. Scheutz, C. Jensen, P. Schiellerup, J. Enberg, A. M. Petersen, B. Olesen, P. Gerner-Smidt, and K. Mølbak. 2004. Virulence factors for hemolytic uremic syndrome, Denmark. Emerg. Infect. Dis. 10:842-847.
6. Friedrich, A. W., M. Bielaszewska, W. L. Zhang, M. Pulz, T. Kuczius, A. Ammon, and H. Karch. 2002. Escherichia coli harboring Shiga toxin 2 gene variants: frequency and association with clinical symptoms. J. Infect. Dis. 185:74-84.
7. Griffin, P. M. 1995. Escherichia coli O157:H7 and other enterohemorrhagic Escherichia coli, p. 739-761. In M. J. Blaser, P. D. Smith, J. I. Ravdin, H. B. Greenberg, and R. L. Guerrant (ed.), Infections of the gastrointestinal tract. Raven Press, New York, NY.
8. Jenkins, C., G. A. Willshaw, J. Evans, T. Cheasty, H. Chart, D. J. Shaw, G. Dougan, G. Frankel, and H. R. Smith. 2003. Subtyping of virulence genes in verocytotoxin-producing Escherichia coli (VTEC) other than serogroup O157 associated with disease in the United Kingdom. J. Med. Microbiol. 52:941-947.
9. Kaper, J. B., J. P. Nataro, and H. L. T. Mobley. 2004. Pathogenic Escherichia coli. Nat. Rev. Microbiol. 2:123-140.
10. Kimmitt, P. T., C. R. Harwood, and M. R. Barer. 2000. Toxin gene expression by Shiga toxin-producing Escherichia coli: the role of antibiotics and the bacterial SOS response. Emerg. Infect. Dis. 6:458-465.
11. Mølbak, K., P. S. Mead, and P. M. Griffin. 2002. Antimicrobial therapy in patients with Escherichia coli O157:H7 infection. JAMA 288:1014-1016.
12. Murakami, J., K. Kishi, K. Hirai, K. Hiramatsu, T. Yamasaki, and M. Nasu. 2000. Macrolides and clindamycin suppress the release of Shiga-like toxins from Escherichia coli O157:H7 in vitro. Int. J. Antimicrob. Agents 15:103-109.
13. Nataro, J. P., and J. B. Kaper. 1998. Diarrheagenic Escherichia coli. Clin. Microbiol. Rev. 11:142-201.
14. Persson, S., K. E. P. Olsen, S. Ethelberg, and F. Scheutz. 2007. Subtyping method for Escherichia coli Shiga toxin (verocytotoxin) 2 variants and correlations to clinical manifestations. J. Clin. Microbiol. 45:2020-2024.
15. Scheutz, F., and N. A. Strockbine. 2005. Escherichia, p. 607-624. In G. M. Garrity, D. J. Brenner, N. R. Krieg, and J. T. Staley (ed.), Bergey's manual of systematic bacteriology. Springer, New York, NY.
16. Tarr, P. I., C. A. Gordon, and W. L. Chandler. 2005. Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome. Lancet 365:1073-1086.
17. Teel, L. D., A. R. Melton-Celsa, C. K. Schmitt, and A. D. O'Brien. 2002. One of two copies of the gene for the activatable Shiga toxin type 2d in Escherichia coli O91:H21 strain B2F1 is associated with an inducible bacteriophage. Infect. Immun. 70:4282-4291.
18. Wagner, P. L., J. Livny, M. N. Neely, D. W. Acheson, D. I. Friedman, and M. K. Waldor. 2002. Bacteriophage control of Shiga toxin 1 production and release by Escherichia coli. Mol. Microbiol. 44:957-970.
19. Wagner, P. L., M. N. Neely, X. Zhang, D. W. K. Acheson, M. K. Waldor, and D. I. Friedman. 2001. Role for a phage promoter in Shiga toxin 2 expression from a pathogenic Escherichia coli strain. J. Bacteriol. 183:2081-2085.
20. Yoh, M., E. K. Frimpong, and T. Honda. 1997. Effect of antimicrobial agents, especially fosfomycin, on the production and release of Vero toxin by enterohaemorrhagic Escherichia coli O157:H7. FEMS Immunol. Med. Microbiol. 19:57-64.
21. Yoh, M., E. K. Frimpong, S. P. Voravuthikunchai, and T. Honda. 1999. Effect of subinhibitory concentrations of antimicrobial agents (quinolones and macrolide) on the production of verotoxin by enterohemorrhagic Escherichia coli O157:H7. Can. J. Microbiol. 45:732-739.
22. Zhang, X., A. D. McDaniel, L. E. Wolf, G. T. Keusch, M. K. Waldor, and D. W. K. Acheson. 2000. Quinolone antibiotics induce Shiga toxin-encoding bacteriophages, toxin production, and death in mice. J. Infect. Dis. 181:664-670.