Neisseria meningitidis intermediately resistant to penicillin and causing invasive disease in South Africa in 2001 to 2005

Journal of Clinical Microbiology

Volumn 46, Issue 10, 2008, Pages 3208-3214

  Du Plessis, Mignon ^a,b,e   Von Gottberg, Anne ^a,b   Cohen, Cheryl ^a,c   De Gouveia, Linda ^a   Klugman, Keith P ^a,d  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^b UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^c UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^d EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e NATIONAL INSTITUTE FOR COMMUNICABLE DISEASES   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIUM ISOLATE; CONTROLLED STUDY; DNA FINGERPRINTING; DNA SEQUENCE; GENE IDENTIFICATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; MOLECULAR EPIDEMIOLOGY; NEISSERIA MENINGITIDIS; NEISSERIACEAE INFECTION; PREVALENCE; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; SOUTH AFRICA;

ALLELES; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CHILD, PRESCHOOL; CLUSTER ANALYSIS; COMORBIDITY; DNA FINGERPRINTING; DNA, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; EPIDEMIOLOGY, MOLECULAR; FEMALE; GENOTYPE; HIV INFECTIONS; HUMANS; INCIDENCE; INFANT; INFANT, NEWBORN; MALE; MENINGOCOCCAL INFECTIONS; MICROBIAL SENSITIVITY TESTS; NEISSERIA MENINGITIDIS; PENICILLIN RESISTANCE; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SEROTYPING; SOUTH AFRICA;

HUMAN IMMUNODEFICIENCY VIRUS; NEISSERIA MENINGITIDIS;

EID: 53649091428     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.00221-08     Document Type: Article

References (51)

1. Antignac, A., J. M. Alonso, and M. K. Taha. 2001. Nonculture prediction of Neisseria meningitidis susceptibility to penicillin. Antimicrob. Agents Chemother. 45:3625-3628.
2. Antignac, A., I. G. Boneca, J. C. Rousselle, A. Namane, J. P. Carlier, J. A. Vazquez, A. Fox, J. M. Alonso, and M. K. Taha. 2003. Correlation between alterations of the penicillin-binding protein 2 and modifications of the peptidoglycan structure in Neisseria meningitidis with reduced susceptibility to penicillin G. J. Biol. Chem. 278:31529-31535.
3. Antignac, A., M. Ducos-Galand, A. Guiyoule, R. Pires, J. M. Alonso, and M. K. Taha. 2003. Neisseria meningitidis strains isolated from invasive infections in France (1999-2002): phenotypes and antibiotic susceptibility patterns. Clin. Infect. Dis. 37:912-920.
4. Antignac, A., P. Kriz, G. Tzanakaki, J. M. Alonso, and M. K. Taha. 2001. Polymorphism of Neisseria meningitidis penA gene associated with reduced susceptibility to penicillin. J. Antimicrob. Chemother. 47:285-296.
5. Arreaza, L., C. Salcedo, B. Alcala, M. J. Uria, R. Abad, R. Enriquez, and J. A. Vazquez. 2004. Sequencing of Neisseria meningitidis penA gene: the key to success in defining penicillin G breakpoints. Antimicrob. Agents Chemother. 48:358-359.
6. Barbour, A. G. 1981. Properties of penicillin-binding proteins in Neisseria gonorrhoeae. Antimicrob. Agents Chemother. 19:316-322.
7. Blondeau, J. M., F. E. Ashton, M. Isaacson, Y. Yaschuck, C. Anderson, and G. Ducasse. 1995. Neisseria meningitidis with decreased susceptibility to penicillin in Saskatchewan, Canada. J. Clin. Microbiol. 33:1784-1786.
8. Boras, A., D. Bozinovic, F. C. Tenover, and T. Popovic. 2001. First report of Neisseria meningitidis intermediately resistant to penicillin in Croatia. J. Clin. Microbiol. 39:823.
9. Botha, P. 1988. Penicillin-resistant Neisseria meningitidis in southern Africa. Lancet i:54.
10. Brannigan, J. A., I. A. Tirodimos, Q. Y. Zhang, C. G. Dowson, and B. G. Spratt. 1990. Insertion of an extra amino acid is the main cause of the low affinity of penicillin-binding protein 2 in penicillin-resistant strains of Neisseria gonorrhoeae. Mol. Microbiol. 4:913-919.
11. Brown, S., G. Riley, and F. Jamieson. 2001. Neisseria meningitidis with decreased susceptibility to penicillin in Ontario, Canada 1997-2000. Can. Commun. Dis. Rep. 27:73-75.
12. Caniça, M., R. Dias, and E. Ferreira. 2004. Neisseria meningitidis C:2b:P1.2,5 with intermediate resistance to penicillin, Portugal. Emerg. Infect. Dis. 10: 526-529.
13. Caniça, M., R. Dias, B. Nunes, L. Carvalho, and E. Ferreira. 2004. Invasive culture-confirmed Neisseria meningitidis in Portugal: evaluation of serogroups in relation to different variables and antimicrobial susceptibility (2000-2001). J. Med. Microbiol. 53:921-925.
14. Centers for Disease Control and Prevention. 2008. Emergence of fluoroquinolone-resistant Neisseria meningitidis - Minnesota and North Dakota, 2007-2008. MMWR Morb. Mortal. Wkly. Rep. 57:173-175.
15. CLSI. 2005. Performance standards for antimicrobial susceptibility testing; fifteenth informational supplement. CLSI document M100-S, 15th ed. CLSI, Wayne, PA.
16. CLSI. 2006. Performance standards for antimicrobial susceptibility testing; sixteenth informational supplement. CLSI document M100-S, 16th ed. CLSI, Wayne, PA.
17. Coulson, G. B., A. von Gottberg, M. du Plessis, A. M. Smith, L. de Gouveia, and K. P. Klugman. 2007. Meningococcal disease in South Africa, 1999-2002. Emerg. Infect. Dis. 13:273-281.
18. Dean, A. D., J. A. Dean, and J. H. Burton. 1996. EpiInfo v6.04: a word processing, database and statistics program for epidemiology on microcomputers. Centers for Disease Control and Prevention, Atlanta, GA.
19. Dougherty, T. J., A. E. Koller, and A. Tomasz. 1981. Competition of betalactam antibiotics for the penicillin-binding proteins of Neisseria gonorrhoeae. Antimicrob. Agents Chemother. 20:109-114.
20. Ferreira, E., and M. Caniça. 2002. Invasive meningococci with reduced susceptibility to penicillin in Portugal. J. Antimicrob. Chemother. 49:424-425.
21. Gagneux, S., A. Hodgson, I. Ehrhard, G. Morelli, B. Genton, T. Smith, M. Tanner, F. Binka, M. Achtman, and G. Pluschke. 2000. Microheterogeneity of serogroup A (subgroup III) Neisseria meningitidis during an outbreak in northern Ghana. Trop. Med. Int. Health 5:280-287.
22. Galimand, M., G. Gerbaud, M. Guibourdenche, J. Y. Riou, and P. Courvalin. 1998. High-level chloramphenicol resistance in Neisseria meningitidis. N. Engl. J. Med. 339:868-874.
23. Gautom, R. K. 1997. Rapid pulsed-field gel electrophoresis protocol for typing of Escherichia coli O157:H7 and other gram-negative organisms in 1 day. J. Clin. Microbiol. 35:2977-2980.
24. Huebner, R. E., K. P. Klugman, U. Matai, R. Eggers, G. Hussey, et al. 1999. Laboratory surveillance for Haemophilus influenzae type B meningococcal, and pneumococcal disease. S. Afr. Med. J. 89:924-925.
25. Jackson, L. A., F. C. Tenover, C. Baker, B. D. Plikaytis, M. W. Reeves, S. A. Stocker, R. E. Weaver, J. D. Wenger, et al. 1994. Prevalence of Neisseria meningitidis relatively resistant to penicillin in the United States, 1991. J. Infect. Dis. 169:438-441.
26. Jackson, L. A., and J. D. Wenger. 1993. Laboratory-based surveillance for meningococcal disease in selected areas, United States, 1989-1991. MMWR CDC Surveill. Summ. 42:21-30.
27. Jolley, K. A., M. S. Chan, and M. C. Maiden. 2004. mlstdbNet - distributed multi-locus sequence typing (MLST) databases. BMC Bioinformatics 5:86.
28. Jones, D. M., and E. M. Sutcliffe. 1990. Meningococci with reduced susceptibility to penicillin. Lancet 335:863-864.
29. Jorgensen, J. H., S. A. Crawford, and K. R. Fiebelkorn. 2005. Susceptibility of Neisseria meningitidis to 16 antimicrobial agents and characterization of resistance mechanisms affecting some agents. J. Clin. Microbiol. 43:3162-3171.
30. Kyaw, M. H., J. C. Bramley, S. Clark, P. Christie, I. G. Jones, and H. Campbell. 2002. Prevalence of moderate penicillin resistant invasive Neisseria meningitidis infection in Scotland, 1994-9. Epidemiol. Infect. 128:149-156.
31. National Department of Health, South Africa. 2006. Standard treatment guidelines and essential drugs list for South Africa: hospital level, adults. http://www.doh.gov.za/docs/index.html.
32. NCCLS. 2004. Performance standards for antimicrobial susceptibility testing; fourteenth informational supplement. NCCLS document M100-S, 14th ed. NCCLS, Wayne, PA.
33. Punar, M., H. Eraksoy, A. A. Cagatay, H. Ozsut, A. Kaygusuz, S. Calangu, and M. Dilmener. 2002. Neisseria meningitidis with decreased susceptibility to penicillin in Istanbul, Turkey. Scand. J. Infect. Dis. 34:11-13.
34. Rådstrom, P., A. Backman, N. Qian, P. Kragsbjerg, C. Pahlson, and P. Olcen. 1994. Detection of bacterial DNA in cerebrospinal fluid by an assay for simultaneous detection of Neisseria meningitidis, Haemophilus influenzae, and streptococci using a seminested PCR strategy. J. Clin. Microbiol. 32: 2738-2744.
35. Rosenstein, N. E., S. A. Stocker, T. Popovic, F. C. Tenover, B. A. Perkins, and the Active Bacterial Core Surveillance (ABCs) Team. 2000. Antimicrobial resistance of Neisseria meningitidis in the United States, 1997. Clin. Infect. Dis. 30:212-213.
36. Sáez-Nieto, J. A., R. Lujan, S. Berron, J. Campos, M. Vinas, C. Fuste, J. A. Vazquez, Q. Y. Zhang, L. D. Bowler, J. V. Martinez-Suarez, et al. 1992. Epidemiology and molecular basis of penicillin-resistant Neisseria meningitidis in Spain: a 5-year history (1985-1989). Clin. Infect. Dis. 14:394-402.
37. Stefanelli, P., C. Fazio, G. La Rosa, C. Marianelli, M. Muscillo, and P. Mastrantonio. 2001. Rifampicin-resistant meningococci causing invasive disease: detection of point mutations in the rpoB gene and molecular characterization of the strains. J. Antimicrob. Chemother. 47:219-222.
38. Stefanelli, P., C. Fazio, A. Neri, T. Sofia, and P. Mastrantonio. 2004. Emergence in Italy of a Neisseria meningitidis clone with decreased susceptibility to penicillin. Antimicrob. Agents Chemother. 48:3103-3106.
39. Taha, M. K. 2000. Simultaneous approach for nonculture PCR-based identification and serogroup prediction of Neisseria meningitidis. J. Clin. Microbiol. 38:855-857.
40. Taha, M. K., J. A. Vazquez, E. Hong, D. E. Bennett, S. Bertrand, S. Bukovski, M. T. Cafferkey, F. Carion, J. J. Christensen, M. Diggle, G. Edwards, R. Enriquez, C. Fazio, M. Frosch, S. Heuberger, S. Hoffmann, K. A. Jolley, M. Kadlubowski, A. Kechrid, K. Kesanopoulos, P. Kriz, L. Lambertsen, I. Levenet, M. Musilek, M. Paragi, A. Saguer, A. Skoczynska, P. Stefanelli, S. Thulin, G. Tzanakaki, M. Unemo, U. Vogel, and M. L. Zarantonelli. 2007. Target gene sequencing to characterize the penicillin G susceptibility of Neisseria meningitidis. Antimicrob. Agents Chemother. 51:2784-2792.
41. Taha, M. K., M. L. Zarantonelli, A. Neri, R. Enriquez, J. A. Vazquez, and P. Stefanelli. 2006. Interlaboratory comparison of PCR-based methods for detection of penicillin G susceptibility in Neisseria meningitidis. Antimicrob. Agents Chemother. 50:887-892.
42. Tenover, F. C., R. D. Arbeit, R. V. Goering, P. A. Mickelsen, B. E. Murray, D. H. Persing, and B. Swaminathan. 1995. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J. Clin. Microbiol. 33:2233-2239.
43. Thulin, S., P. Olcen, H. Fredlund, and M. Unemo. 2006. Total variation in the penA gene of Neisseria meningitidis: correlation between susceptibility to beta-lactam antibiotics and penA gene heterogeneity. Antimicrob. Agents Chemother. 50:3317-3324.
44. Van Esso, D., D. Fontanals, S. Uriz, M. A. Morera, T. Juncosa, C. Latorre, and M. Duran. 1987. Neisseria meningitidis strains with decreased susceptibility to penicillin. Pediatr. Infect. Dis. J. 6:438-439.
45. Vázquez, J. A., L. Arreaza, C. Block, I. Ehrhard, S. J. Gray, S. Heuberger, S. Hoffmann, P. Kriz, P. Nicolas, P. Olcen, A. Skoczynska, L. Spanjaard, P. Stefanelli, M. K. Taha, and G. Tzanakaki. 2003. Interlaboratory comparison of agar dilution and Etest methods for determining the MICs of antibiotics used in management of Neisseria meningitidis infections. Antimicrob. Agents Chemother. 47:3430-3434.
46. Vázquez, J. A., A. M. Enriquez, L. de la Fuente, S. Berron, and M. Baquero. 1996. Isolation of a strain of beta-lactamase-producing Neisseria meningitidis in Spain. Eur. J. Clin. Microbiol. Infect. Dis. 15:181-182.
47. von Gottberg, A., M. du Plessis, C. Cohen, E. Prentice, S. Schrag, L. de Gouveia, G. Coulson, G. de Jong, and K. Klugman. 2008. Emergence of endemic serogroup W135 meningococcal disease associated with a high mortality rate in South Africa. Clin. Infect. Dis. 46:377-386.
48. Winn, W. C. J., S. D. Allen, W. M. Janda, E. M. Koneman, G. W. Procop, P. C. Schreckenberger, and G. L. Woods. 2006. Koneman's color atlas and textbook of diagnostic microbiology, 6th ed., p. 566-622. Lippincott Williams & Wilkins, Philadelphia, PA.
49. Woods, C. R., A. L. Smith, B. L. Wasilauskas, J. Campos, and L. B. Givner. 1994. Invasive disease caused by Neisseria meningitidis relatively resistant to penicillin in North Carolina. J. Infect. Dis. 170:453-456.
50. World Health Organization. 2007. Control of epidemic meningococcal disease. WHO practical guidelines, 2nd ed. WHO_EMC/BAC/98/3/ www.who.int/csr/resources/publications/meningitis/WHO_EMC_BAC_98_3_EN/en/.
51. Zerouali, K., N. Elmdaghri, M. Boudouma, and M. Benbachir. 2002. Serogroups, serotypes, serosubtypes and antimicrobial susceptibility of Neisseria meningitidis isolates in Casablanca, Morocco. Eur. J. Clin. Microbiol. Infect. Dis. 21:483-485.