An expedient synthesis of 3-substituted indoles via reductive alkylation with ketones

Tetrahedron Letters

Volumn 49, Issue 48, 2008, Pages 6749-6751

  Rizzo, John R ^a   Alt, Charles A ^a   Zhang, Tony Y ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INDOLE DERIVATIVE; KETONE DERIVATIVE;

ALKYLATION; ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; REACTION ANALYSIS; REDUCTION; STRUCTURE ANALYSIS; SUBSTITUTION REACTION; SYNTHESIS;

EID: 53649083269     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2008.08.034     Document Type: Article

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11. 3) 7.9 (1H, br s), 7.7 (1H, d), 7.4 (1H), 7.3 (1H, m), 7.2 (1H, m), 7.0 (1H, s), 3.3 (1H, m), 2.2 (2H, m), 1.9 (1H, m), 1.8 (3H, m), 1.0 (1H, m), 1.6 (1H, m); HRMS theory 185.1204, found 185.1212.
12. All products were isolated and characterized using NMR, IR, and HRMS.