Protein-induced changes during the maturation process of human dendritic cells: A 2-D DIGE approach

Proteomics - Clinical Applications

Volumn 2, Issue 9, 2008, Pages 1349-1360

  Ferreira, Gabriela Bomfim ^a   Overbergh, Lut ^a   van Etten, Evelyne ^a   Lage, Kasper ^b   D'Hertog, Wannes ^a   Hansen, Daniel Aaen ^b   Maris, Michael ^a   Moreau, Yves ^c   Workman, Christopher T ^b   Waelkens, Etienne ^a   Mathieu, Chantal ^a  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^c UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

2 D DIGE; Dendritic cell; Maturation; Network

Indexed keywords

ALPHA ENOLASE; APOLIPOPROTEIN; APOLIPOPROTEIN L2; BETA N ACETYLHEXOSAMINIDASE; BETA N ACETYLHEXOSAMINIDASE BETA CHAIN; CATHEPSIN B; CATHEPSIN D; CATHEPSIN S; CD11B ANTIGEN; CD14 ANTIGEN; CYTOSOL AMINOPEPTIDASE; DIHYDROLIPOAMIDE DEHYDROGENASE; FASCIN; LAMIN A; MALATE DEHYDROGENASE; PROTEIN SERINE THREONINE KINASE; PROTEIN SERINE THREONINE KINASE 4; PROTEIN TYROSINE PHOSPHATASE; PYRUVATE CARBOXYLASE; PYRUVATE KINASE; RIBONUCLEOPROTEIN; RIBONUCLEOPROTEIN H; SERINE PROTEINASE INHIBITOR; SERINE PROTEINASE INHIBITOR 9; SERUM ALBUMIN; SPHINGOLIPID ACTIVATOR PROTEIN 2; STAT5A PROTEIN; SUPEROXIDE DISMUTASE; THYMIDINE PHOSPHORYLASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIGEN PRESENTATION; ARTICLE; CELL MATURATION; CONTROLLED STUDY; DENDRITIC CELL; HUMAN; HUMAN CELL; IMMUNOPATHOLOGY; PERIPHERAL BLOOD MONONUCLEAR CELL; PH; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PROCESSING; TWO DIMENSIONAL DIFFERENCE GEL ELECTROPHORESIS; TWO DIMENSIONAL GEL ELECTROPHORESIS;

EID: 53549128367     PISSN: 18628346     EISSN: None     Source Type: Journal    
DOI: 10.1002/prca.200800110     Document Type: Article

References (33)

1. Banchereau, J., Briere, F., Caux, C., Davoust, J. et al., Immunobiology of dendritic cells. Annu. Rev. Immunol. 2000, 18, 767-811.
2. Hawiger, D., Inaba, K., Dorsett, Y., Guo, M. et al., Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J. Exp. Med. 2001, 194, 769-779.
3. Sotomayor, E. M., Borrello, I., Rattis, F. M., Cuenca, A. G. et al., Cross-presentation of tumor antigens by bone marrow-derived antigen-presenting cells is the dominant mechanism in the induction of T-cell tolerance during B-cell lymphoma progression. Blood 2001, 98, 1070-1077.
4. Jonuleit, H., Schmitt, E., Stassen, M., Tuettenberg, A. et al., Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood. J. Exp. Med. 2001, 193, 1285-1294.
5. Banchereau, J., Steinman, R. M., Dendritic cells and the control of immunity. Nature 1998, 392, 245-252.
6. Adema, G. J., Hartgers, F., Verstraten, R., de Vries, E. et al., A dendritic-cell-derived C-C chemokine that preferentially attracts naive T cells. Nature 1997, 387, 713-717.
7. Brocker, T., Survival of mature CD4 T lymphocytes is dependent on major histocompatibility complex class II-expressing dendritic cells. J. Exp. Med. 1997, 186, 1223-1232.
8. Granucci, F., Zanoni, I., Feau, S., Ricciardi-Castagnoli, P., Dendritic cell regulation of immune responses: a new role for interleukin 2 at the intersection of innate and adaptive immunity. EMBO J. 2003, 22, 2546-2551.
9. Ahn, J. H., Lee, Y., Jeon, C., Lee, S. J. et al., Identification of the genes differentially expressed in human dendritic cell subsets by cDNA subtraction and microarray analysis. Blood 2002, 100, 1742-1754.
10. Baltathakis, I., Alcantara, O., Boldt, D. H., Expression of different NF-kappaB pathway genes in dendritic cells (DCs) or macrophages assessed by gene expression profiling. J. Cell Biochem. 2001, 83, 281-290.
11. Chen, Z., Gordon, J. R., Zhang, X., Xiang, J., Analysis of the gene expression profiles of immature versus mature bone marrow-derived dendritic cells using DNA arrays. Biochem. Biophys. Res. Commun. 2002, 290, 66-72.
12. Ju, X. S., Hacker, C., Madruga, J., Kurz, S. M. et al., Towards determining the differentiation program of antigen-presenting dendritic cells by transcriptional profiling. Eur. J. Cell Biol. 2003, 82, 75-86.
13. Angenieux, C., Fricker, D., Strub, J. M., Luche, S. et al., Gene induction during differentiation of human monocytes into dendritic cells: An integrated study at the RNA and protein levels. Funct. Integr. Genomics 2001, 1, 323-329.
14. Le Naour, F., Hohenkirk, L., Grolleau, A., Misek, D. E. et al., Profiling changes in gene expression during differentiation and maturation of monocyte-derived dendritic cells using both oligonucleotide microarrays and proteomics. J. Biol. Chem. 2001, 276, 17920-17931.
15. Pereira, S. R., Faca, V. M., Gomes, G. G., Chammas, R. et al., Changes in the proteomic profile during differentiation and maturation of human monocyte-derived dendritic cells stimulated with granulocyte macrophage colony stimulating factor/interleukin-4 and lipopolysaccharide. Proteomics 2005, 5, 1186-1198.
16. Horlock, C., Shakib, F., Mahdavi, J., Jones, N. S. et al., Analysis of proteomic profiles and functional properties of human peripheral blood myeloid dendritic cells, monocyte-derived dendritic cells and the dendritic cell-like KG-1 cells reveals distinct characteristics. Genome Biol. 2007, 8, R30.
17. Rivollier, A., Perrin-Cocon, L., Luche, S., Diemer, H. et al., High expression of antioxidant proteins in dendritic cells: possible implications in atherosclerosis. Mol. Cell. Proteomics 2006, 5, 726-736.
18. Watarai, H., Hinohara, A., Nagafune, J., Nakayama, T. et al., Plasma membrane-focused proteomics: dramatic changes in surface expression during the maturation of human dendritic cells. Proteomics 2005, 5, 4001-4011.
19. Richards, J., Le Naour, F., Hanash, S., Beretta, L., Integrated genomic and proteomic analysis of signaling pathways in dendritic cell differentiation and maturation. Ann. NY Acad. Sci. 2002, 975, 91-100.
20. D'Hertog, W., Overbergh, L., Lage, K., Ferreira, G. B. et al., Proteomics analysis of cytokine-induced dysfunction and death in insulin-producing INS-1E cells: new insights into the pathways involved. Mol. Cell. Proteomics 2007, 6, 2180-2199.
21. Hinsby, A. M., Kiemer, L, Karlberg, E. O., Lage, K. et al., A wiring of the human nucleolus. Mol. Cell 2006, 22, 285-295.
22. Lage, K., Karlberg, E. O., Storling, Z. M., Olason, P. I. et al., A human phenome-interactome network of protein complexes implicated in genetic disorders. Nat. Biotechnol. 2007, 25, 309-316.
23. Macagno, A., Gilliet, M., Sallusto, F., Lanzavecchia, A. et al., Dendritic cells up-regulate immunoproteasomes and the proteasome regulator PA28 during maturation. Eur. J. Immunol. 1999. 29, 4037-4042.
24. Fruh, K., Yang, Y., Antigen presentation by MHC class I and its regulation by interferon gamma. Curr. Opin. Immunol. 1999, 11, 76-81.
25. Kos, J., Sekirnik, A., Premzl, A., Zavasnik Bergant, V. et al., Carboxypeptidases cathepsins X and B display distinct protein profile in human cells and tissues. Exp. Cell Res. 2005, 306, 103-113.
26. Deussing, J., Roth, W., Saftig, P., Peters, C. et al., Cathepsins B and D are dispensable for major histocompatibility complex class II-mediated antigen presentation. Proc. Natl. Acad. Sci. USA 1998, 95, 4516-4521.
27. Riese, R. J., Wolf, P. R., Brömme, D., Natkin, L. R. et al., Essential Role for Cathepsin S in MHC Class II-Associated Invariant Chain Processing and Peptide Loading. Immunity 1996, 4, 357-366.
28. Villadangos, J. A., Riese. R. J., Peters, C., Chapman, H. A. et al., Degradation of mouse invariant chain: roles of cathepsins S and D and the influence of major histocompatibility complex polymorphism. J. Exp. Med. 1997. 186, 549-560.
29. Accola, M. A., Huang, B., Al Masri, A., McNiven, M. A., The antiviral dynamin family member, MxA, tubulates lipids and localizes to the smooth endoplasmic reticulum. J. Biol. Chem. 2002, 277, 21829-21835.
30. Nagano, K., Masters, J. R., Akpan, A., Yang, A. et al., Differential protein synthesis and expression levels in normal and neoplastic human prostate cells and their regulation by type I and II interferons. Oncogene 2004, 23, 1693-1703.
31. Schroer, T. A., Microtubules don and doff their caps: Dynamic attachments at plus and minus ends. Curr. Opin. Cell Biol. 2001, 13, 92-96.
32. King, S. M., Witman, G. B., Localization of an intermediate chain of outer arm dynein by immunoelectron microscopy. J. Biol. Chem. 1990, 265, 19807-19811.
33. Stow, J. L., Manderson, A. P., Murray, R. Z., SNAREing immunity: The role of SNAREs in the immune system. Nat. Rev. Immunol. 2006, 6, 919-929.