Harpooning the Cvt complex to the phagophore assembly site

Autophagy

Volumn 4, Issue 7, 2008, Pages 914-916

  Monastyrska, Iryna ^a   Reggiori, Fulvio ^a   Klionsky, Daniel J ^b  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Actin filaments; Autophagy; Cvt pathway; Phagophore assembly site; Yeast

Indexed keywords

ACTIN RELATED PROTEIN 2-3 COMPLEX;

ACTIN FILAMENT; ARTICLE; AUTOPHAGY; CELL VACUOLE; CYTOPLASM; LYSOSOME; MEMBRANE VESICLE; NONHUMAN; PHAGOPHORE ASSEMBLY SITE; PHAGOSOME; YEAST;

EUKARYOTA;

EID: 53549119394     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.6657     Document Type: Article

References (20)

1. Harding TM, Morano KA, Scott SV, Klionsky DJ. Isolation and characterization of yeasr mutants in the cytoplasm to vacuole protein targering pathway. J Cell Biol 1995; 131:591-602.
2. Baba M, Osumi M, Scott SV, Klionsky DJ, Ohsumi Y. Two distinct parhways for Targeting proreins from the cytoplasm to the vacuole/lysosome. J Cell Biol 1997; 139:1687-95.
3. Xie Z, Nair U, Klionsky DJ. Arg8 controls phagophore expansion during autophagosome formation. Mol Biol Cell 2008; 19:3290-8.
4. Yen W-L, Legakis JE, Nair U, Klionsky DJ. Atg27 is required for autophagy-dependent cycling of Atg9. Mol Biol Cell 2007; 18:581-93.
5. Reggiori F, Monastyrska I, Shintani T, Klionsky DJ. The actin cytoskeleton is required for selective types of autophagy, but not nonspecific autophagy, in the yeast Saccharomyces cerevisiae. Mol Biol Cell 2005; 16:5843-56.
6. Shintani T, Huang W-P, Stromhaug PE, Klionsky DJ. Mechanism of cargo selection in the cytoplasm to vacuole Targeting parhway. Dev Cell 2002; 3:825-37.
7. Shintani T, Klionsky DJ. Cargo proteins facilitate the formation of transport vesicles in the cytoplasm to vacuole targeting parhway. J Biol Chem 2004; 279:29889-94.
8. Yorimitsu T, Klionsky DJ. Arg11 links cargo to the vesicle-forming machinery in the cytoplasm to vacuole targeting pathway. Mol Biol Cell 2005; 16:1593-605.
9. He C, Song H, Yorimitsu T, Monastyrska I, Yen W-L, Legakis JE, Klionsky DJ. Recruitment of Atg9 to the preautophagosomal structure by Atg11 is essential for selective autophagy in budding yeast. J Cell Biol 2006; 175:925-35.
10. Noda T, Kim J, Huang W-P, Baba M, Tokunaga C, Ohsumi Y, Klionsky DJ. Apg9p/Cvt7p is an integral membrane protein required for transport vesicle formation in the Cvt and autophagy pathways. J Cell Biol 2000; 148:465-80.
11. Legakis JE, Yen W-L, Klionsky DJ. A cycling protein complex required for selective autophagy. Autophagy 2007; 3:422-32.
12. Reggiori F, Shintani T, Nair U, Klionsky DJ. Atg9 cycles between mitochondria and the pre-autophagosomal structure in yeasts. Autophagy 2005; 1:101-9.
13. Boldogh IR, Yang H-C, Nowakowski WD, Karmon SL, Hays LG, Yates JR, III, Pon LA. Arp2/3 complex and actin dynamics are required for actin-based mitochondrial motility in yeast. Proc Natl Acad Sci USA 2001; 98:3162-7.
14. Winder SJ, Ayscough KR. Actin-binding proteins. J Cell Sci 2005; 118:651-4.
15. Monastyrska I, He C, Geng J, Hoppe AD, Li Z, Klionsky DJ. Arp2 links autophagic machinery with the actin cytoskeleton. Mol Biol Cell 2008; 19:1962-75.
16. Goldberg MB. Actin-based motility of intracellular microbial pathogens. Microbiol Mol Biol Rev 2001; 65:595-626.
17. Merrifield CJ, Moss SE, Ballestrem C, Imhof BA, Giese G, Wunderlich I, Almers W. Endocytic vesicles move at the tips of actin tails in cultured mast cells. Nat Cell Biol 1999; 1:72-4.
18. Monastyrska I, Shintani T, Klionsky DJ, Reggiori F. Atg11 directs autophagosome cargoes to the PAS along actin cables. Autophagy 2006; 2:119-21.
19. Kaksonen M, Sun Y, Drubin DG. A pathway for association of receptors, adaptors, and actin during endocytic internalization. Cell 2003; 115:475-87.
20. Vida TA, Emr SD. A new vital stain for visualizing vacuolar membrane dynamics and endocytosis in yeast. J Cell Biol 1995; 128:779-92.