Development of an in vitro reproductive screening assay for novel pharmaceutical compounds

Biotechnology and Applied Biochemistry

Volumn 51, Issue 2, 2008, Pages 63-71

  Edwards, Vicki ^a   Markovic, Elda ^b   Matisons, Janis ^b   Young, Fiona ^a  

^a FLINDERS UNIVERSITY   (Australia)

^b FLINDERS UNIVERSITY   (Australia)

Author keywords

3 (4,5 dimethylthiazol 2 yl) 2; 5 diphenyl 2H tetrazolium bromide (MTT); Human chorionic gonadotropin; In vitro reproductive screening; Murine Leydig tumour cell line (MLTC 1); Nanopharmaceutical; Reproductive toxicity

Indexed keywords

CELL ADHESION; CELL CULTURE; CELLS; CYTOLOGY; ETHERS; ETHYLENE; ETHYLENE GLYCOL; GLYCOLS; ORGANIC COMPOUNDS; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; TOXICITY; TUMORS;

3-(4,5-DIMETHYLTHIAZOL-2-YL)-2; 5-DIPHENYL-2H-TETRAZOLIUM BROMIDE (MTT); HUMAN CHORIONIC GONADOTROPIN; IN VITRO REPRODUCTIVE SCREENING; MURINE LEYDIG TUMOUR CELL LINE (MLTC-1); NANOPHARMACEUTICAL; REPRODUCTIVE TOXICITY;

ASSAYS;

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 3 (4,5 DIMETHYLTHIAZOL 2 YL) 5 (3 CARBOXYMETHOXYPHENYL) 2 (4 SULFOPHENYL) 2H TETRAZOLIUM; CHORIONIC GONADOTROPIN; ETHER DERIVATIVE; ETHYLENE GLYCOL MONO ALLYL ETHER; HYDROGEN PEROXIDE; MACROGOL; PROGESTERONE; TETRAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL CELL; ANIMAL MODEL; ARTICLE; ASSAY; CANCER CELL CULTURE; CELL ADHESION; CELL PROTECTION; CYTOTOXICITY; CYTOTOXICITY TEST; INCUBATION TIME; INTERMETHOD COMPARISON; LEYDIG CELL TUMOR; MOUSE; NANOTECHNOLOGY; NONHUMAN; OLIGOMERIZATION; PROGESTERONE SYNTHESIS; REPRODUCIBILITY; REPRODUCTIVE PROCEDURES; REPRODUCTIVE TOXICITY; SCREENING;

ANIMALS; CELL COUNT; CELL LINE, TUMOR; CELL PROLIFERATION; CHORIONIC GONADOTROPIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; ETHYLENE GLYCOL; GENTIAN VIOLET; MALE; MICE; MICE, INBRED C57BL; MOLECULAR STRUCTURE; ORGANOSILICON COMPOUNDS; PROGESTERONE; RADIOIMMUNOASSAY; REPRODUCIBILITY OF RESULTS; TETRAZOLIUM SALTS; THIAZOLES; TOXICITY TESTS;

ANIMALIA; MURINAE;

EID: 53549106385     PISSN: 08854513     EISSN: None     Source Type: Journal    
DOI: 10.1042/BA20070223     Document Type: Article

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