Age-related cone abnormalities in zebrafish with genetic lesions in sonic hedgehog

Investigative Ophthalmology and Visual Science

Volumn 49, Issue 10, 2008, Pages 4631-4640

  Stenkamp, Deborah L ^a   Satterfield, Rosanna ^a   Muhunthan, Kalyani ^a   Sherpa, Tshering ^a   Vihtelic, Thomas S ^b   Cameron, David A ^c  

^a UNIVERSITY OF IDAHO   (United States)

^b UNIVERSITY OF NOTRE DAME   (United States)

^c State University of New York Upstate Medical University: College of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; SONIC HEDGEHOG PROTEIN; OPSIN; SHORT WAVELENGTH OPSIN; SHORT-WAVELENGTH OPSIN; ZEBRAFISH PROTEIN;

AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL AGGREGATION; CELL REGENERATION; CELL TYPE; CONTROLLED STUDY; GENE EXPRESSION; GENE FREQUENCY; GENOTYPE; HETEROZYGOTE; IN SITU HYBRIDIZATION; LIGHT; NONHUMAN; PHENOTYPE; PHOTORECEPTOR; PHOTOTOXICITY; PRIORITY JOURNAL; RETINA; RETINA CELL; RETINA CONE; RETINA CONE ABNORMALITY; RETINA DISEASE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENESCENCE; SIBLING; SIGNAL TRANSDUCTION; WILD TYPE; ZEBRA FISH; ALLELE; ANIMAL; CELL DEATH; CELL PROLIFERATION; FLUORESCENCE MICROSCOPY; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; METABOLISM; MUTATION; NICK END LABELING; PATHOLOGY; PHYSIOLOGY; RADIATION EXPOSURE; RADIATION INJURY; RETINA DEGENERATION;

AGING; ALLELES; ANIMALS; CELL DEATH; CELL PROLIFERATION; CONES (RETINA); FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENE EXPRESSION; HEDGEHOG PROTEINS; IN SITU HYBRIDIZATION; IN SITU NICK-END LABELING; LIGHT; MICROSCOPY, FLUORESCENCE; MUTATION; OPSIN; RADIATION INJURIES, EXPERIMENTAL; RETINA; RETINAL DEGENERATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 53449089162     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.07-1224     Document Type: Article

References (61)

1. Stenkamp DL. Multiple roles for hedgehog signaling in zebrafish eye development. In Fisher CE, Howie SEM, eds. Shh and Gli Signaling and Development. Landes Bioscience; Georgetown, TX; 2006;58-68.
2. Wallace VA. Proliferative and cell fate effects of Hedgehog signaling in the vertebrate retina. Brain Res. 2008;1192:61-75.
3. Wallace VA, Raff MC. A role for Sonic hedgehog in axon-to-astrocyte signalling in the rodent optic nerve. Development. 1999;126(13):2901-2909.
4. Neumann CJ, Nuesslein-Volhard C. Patterning of the zebrafish retina by a wave of sonic hedgehog activity. Science. 2000;289(5487):2137-2139. (Pubitemid 30736522)
5. Zhang XM, Yang XJ. Regulation of retinal ganglion cell production by Sonic hedgehog. Development. 2001;128(6):943-957. (Pubitemid 32288204)
6. Shkumatava A, Fischer S, Müller F, Strahle U, Neumann CJ. Sonic hedgehog, secreted by amacrine cells, acts as a short-range signal to direct differentiation and lamination in the zebrafish retina. Development. 2004;131(16):3849-3858. (Pubitemid 39232146)
7. Stenkamp DL, Frey RA, Prabhudesai SN, Raymond PA. Function for Hedgehog genes in zebrafish retinal development. Dev Biol. 2000;220(2):238-252.
8. Perron M, Boy S, Amato MA, et al. A novel function for Hedgehog signalling in retinal pigment epithelium differentiation. Development. 2003;130(8):1565-1577. (Pubitemid 36527517)
9. Levine EM, Roelink H, Turner J, Reh TA. Sonic hedgehog promotes rod photoreceptor differentiation in mammalian retinal cells in vitro. J Neurosci. 1997;17(16):6277-6288. (Pubitemid 27329902)
10. Wan J, Zheng H, Xiao HL, She ZJ, Zhou GM. Sonic hedgehog promotes stem-cell potential of Muller glia in the mammalian retina. Biochem Biophys Res Commun. 2007;363(2):347-354. (Pubitemid 47484339)
11. Yu C, Mazerolle CJ, Thurig S, et al. Direct and indirect effects of hedgehog pathway activation in the mammalian retina. Mol Cell Neurosci. 2006;32(3):274-282. (Pubitemid 44040966)
12. Stenkamp DL, Frey RA. Extraretinal and retinal hedgehog signaling sequentially regulate retinal differentiation in zebrafish. Dev Biol. 2003;258(2):349-363.
13. Stenkamp DL, Frey RA, Mallory DE, Shupe EE. Embryonic retinal gene expression in sonic-you mutant zebrafish. Dev Dyn. 2002;225(3):344-350. (Pubitemid 35265812)
14. Schauerte HE, van Eeden FJ, Fricke C, Odenthal J, Strähle U, Haffter P. Sonic hedgehog is not required for the induction of medial floor plate cells in the zebrafish. Development. 1998;125(15):2983-2993. (Pubitemid 28410222)
15. Szamier RB, Berson EL. Retinal ultrastructure in advanced retinitis pigmentosa. Invest Ophthalmol Vis Sci. 1977;16(10):947-962.
16. Michaelides M, Hardcastle AJ, Hunt DM, Moore AT. Progressive cone and cone-rod dystrophies: phenotypes and underlying molecular genetic basis. Surv Ophthalmol. 2006;51(3):232-258.
17. Wang DY, Chan WM, Tam PO, et al. Gene mutations in retinitis pigmentosa and their clinical implications. Clin Chim Acta. 2005;351(1-2):5-16. (Pubitemid 39563554)
18. Dalke C, Graw J. Mouse mutants as models for congenital retinal disorders. Exp Eye Res. 2005;81(5):503-512. (Pubitemid 41531996)
19. Raymond PA, Barthel LK, Rounsifer ME, Sullivan SA, Knight JK. Expression of rod and cone visual pigments in goldfish and zebrafish: a rhodopsin-like gene is expressed in cones. Neuron. 1993;10(6):1161-1174.
20. Stenkamp DL, Cameron DA. Cellular pattern formation in the retina: retinal regeneration as a model system. Mol Vis. 2002;8:280-293. (Pubitemid 36153618)
21. Easter SS Jr, Malicki JJ. The zebrafish eye: developmental and genetic analysis. Results Probl Cell Differ. 2002;40:346-370.
22. Stenkamp DL. Neurogenesis in the fish retina. Int Rev Cytol. 2007;259:173-224.
23. Krock BL, Bilotta J, Perkins BD. Noncell-autonomous photoreceptor degeneration in a zebrafish model of choroideremia. Proc Natl Acad Sci U S A. 2007;104(11):4600-4605. (Pubitemid 47186271)
24. Keller ET, Murtha JM. The use of mature zebrafish (Danio rerio) as a model for human aging and disease. Comp Biochem Physiol C Toxicol Pharmacol. 2004;138(3):335-341. (Pubitemid 39469068)
25. Kishi S, Uchiyama J, Baughman AM, Goto T, Lin MC, Tsai SB. The zebrafish as a vertebrate model of functional aging and very gradual senescence. Exp Gerontol. 2003;38(7):777-786. (Pubitemid 36802406)
26. Vihtelic TS, Hyde DR. Light-induced rod and cone cell death and regeneration in the adult albino zebrafish (Danio rerio) retina. J Neurobiol. 2000;44(3):289-307.
27. Hitchcock P, Ochocinska M, Sieh A, Otteson D. Persistent and injury-induced neurogenesis in the vertebrate retina. Prog Retin Eye Res. 2004;23(2):183-194. (Pubitemid 38496400)
28. Maaswinkel H, Riesbeck LE, Riley ME, et al. Behavioral screening for nightblindness mutants in zebrafish reveals three new loci that cause dominant photoreceptor cell degeneration. Mech Ageing Dev. 2005;126(10):1079-1089. (Pubitemid 41253859)
29. Maaswinkel H, Mason B, Li L. ENU-induced late-onset night blindness associated with rod photoreceptor cell degeneration in zebrafish. Mech Ageing Dev. 2003;124(10-12):1065-1071. (Pubitemid 37500832)
30. Westerfield M. The Zebrafish Book: A Guide for the Laboratory Use of Zebrafish (Danio rerio). 4th ed. Eugene, OR: University of Oregon Press; 2000.
31. Otteson DC, D'Costa AR, Hitchcock PF. Putative stem cells and the lineage of rod photoreceptors in the mature retina of the goldfish. Dev Biol. 2001;232(1):62-76.
32. Sherpa T, Fimbel SM, Mallory DE, et al. Ganglion cell regeneration following whole-retina destruction in zebrafish. Dev Neurobiol. 2008;68:166-181. (Pubitemid 351199415)
33. Vihtelic TS, Soverly JE, Kassen SC, Hyde DR. Retinal regional differences in photoreceptor cell death and regeneration in light-lesioned albino zebrafish. Exp Eye Res. 2006;82(4):558-575.
34. Kassen SC, Ramanan V, Montgomery JE, et al. Time course analysis of gene expression during light-induced photoreceptor cell death and regeneration in albino zebrafish. Dev Neurobiol. 2007;67(8):1009-1031. (Pubitemid 47343746)
35. Barthel LK, Raymond PA. Improved method for obtaining 3-microns cryosections for immunocytochemistry. J Histochem Cytochem. 1990;38(9):1383- 1388.
36. Stenkamp DL, Powers MK, Carney LH, Cameron DA. Evidence for two distinct mechanisms of neurogenesis and cellular pattern formation in regenerated goldfish retinas. J Comp Neurol. 2001;431(4):363-381.
37. Cameron DA, Carney LH. Cell mosaic patterns in the native and regenerated inner retina of zebrafish: implications for retinal assembly. J Comp Neurol. 2000;416(3):356-367.
38. Grieg-Smith P. Quantitative Plant Ecology. 2nd ed. London: Butterworth; 1964.
39. Cook JE. Spatial properties of retinal mosaics: an empirical evaluation of some existing measures. Vis Neurosci. 1996;13(1):15-30.
40. DeCarvalho AC, Cappendijk SL, Fadool JM. Developmental expression of the POU domain transcription factor Brn-3b (Pou4f2) in the lateral line and visual system of zebrafish. Dev Dyn. 2004;229(4):869-876.
41. Rozen S, Skaletsky H. Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol. 2000;132:365-386.
42. Larison KD, Bremiller R. Early onset of phenotype and cell patterning in the embryonic zebrafish retina. Development. 1990;109(3):567-576. (Pubitemid 20228651)
43. Fimbel SM, Montgomery JE, Burket CT, Hyde DR. Regeneration of inner retinal neurons after intravitreal injection of ouabain in zebrafish. J Neurosci. 2007;27(7):1712-1724
44. Fausett BV, Goldman D. A role for alpha1 tubulin-expressing Muller glia in regeneration of the injured zebrafish retina. J Neurosci. 2006;26(23):6303-6313.
45. Yurco P, Cameron DA. Responses of Muller glia to retinal injury in adult zebrafish. Vision Res. 2005;45(8):991-1002. (Pubitemid 40203370)
46. Concordet JP, Lewis KE, Moore JW, et al. Spatial regulation of a zebrafish patched homologue reflects the roles of sonic hedgehog and protein kinase A in neural tube and somite patterning. Development. 1996;122(9):2835- 2846.
47. Marcus RC, Delaney CL, Easter SS Jr. Neurogenesis in the visual system of embryonic and adult zebrafish (Danio rerio). Vis Neurosci. 1999;16(3):417-424. (Pubitemid 29245409)
48. Moshiri A, McGuire CR, Reh TA. Sonic hedgehog regulates proliferation of the retinal ciliary marginal zone in posthatch chicks. Dev Dyn. 2005;233(1):66-75. (Pubitemid 40548024)
49. Spence JR, Madhavan M, Ewing JD, et al. The hedgehog pathway is a modulator of retina regeneration. Development. 2004;131(18):4607-4621. (Pubitemid 39409700)
50. Chamberlain M, Baird P, Dirani M, Guymer R. Unraveling a complex genetic disease: age-related macular degeneration. Surv Ophthalmol. 2006;51(6):576-586. (Pubitemid 44667703)
51. Javitt, NB. Oxysterols: functional significance in fetal development and the maintenance of normal retinal function. Curr Opin Lipidol. 2007;18(3):283-288. (Pubitemid 46743052)
52. Fliesler SJ, Peachey NS, Richards MJ, Nagel BA, Vaughan DK. Retinal degeneration in a rodent model of Smith-Lemli-Opitz syndrome: electrophysiologic, biochemical, and morphologic features. Arch Ophthalmol. 2004;122(8):1190-1200.
53. Cohen MM Jr. The hedgehog signaling network. Am J Med Genet A. 2003;123(1):5-28.
54. Curcio CA. Photoreceptor topography in ageing and age-related maculopathy. Eye. 2001;15:376-383.
55. Reme CE, Grimm C, Hafezi F, Iseli HP, Wenzel A. Why study rod cell death in retinal degenerations and how? Doc Ophthalmol. 2003;106(1):25-29. (Pubitemid 36355968)
56. Chader GJ. Animal models in research on retinal degenerations: past progress and future hope. Vision Res. 2002;42(4):393-399.
57. Leveillard T, Mohand-Saïd S, Lorentz O, et al. Identification and characterization of rod-derived cone viability factor. Nat Genet. 2004;36(7):755-759. (Pubitemid 38886639)
58. Michaelides M, Hunt DM, Moore AT. The cone dysfunction syndromes. Br J Ophthalmol. 2004;88(2):291-297.
59. Simunovic MP, Moore AT. The cone dystrophies. Eye. 1998;12:553-565.
60. Biehlmaier O, Neuhauss SC, Kohler K. Double cone dystrophy and RPE degeneration in the retina of the zebrafish gnn mutant. Invest Ophthalmol Vis Sci. 2003;44(3):1287-1298. (Pubitemid 36297852)
61. Morris AC, Schroeter EH, Bilotta J, Wong RO, Fadool JM. Cone survival despite rod degeneration in XOPS-mCFP transgenic zebrafish. Invest Ophthalmol Vis Sci. 2005;46(12):4762-4771. (Pubitemid 44264582)