Intraoperative low-dose ketamine does not prevent a remifentanil-induced increase in morphine requirement after pediatric scoliosis surgery

Anesthesia and Analgesia

Volumn 107, Issue 4, 2008, Pages 1170-1175

  Engelhardt, Thomas ^a   Zaarour, Christian ^a   Naser, Basem ^a   Pehora, Carolyne ^a   De Ruiter, Joost ^a   Howard, Andrew ^a   Crawford, Mark W ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DIPHENHYDRAMINE; GLYCOPYRRONIUM BROMIDE; KETAMINE; MORPHINE; ONDANSETRON; PARACETAMOL; PROPOFOL; REMIFENTANIL; ROCURONIUM; SODIUM CHLORIDE; ANALGESIC AGENT; INTRAVENOUS ANESTHETIC AGENT; NARCOTIC ANALGESIC AGENT; PIPERIDINE DERIVATIVE;

ADOLESCENT; ADULT; ANESTHESIA INDUCTION; ARTICLE; CHILD; CLINICAL ARTICLE; CONTINUOUS INFUSION; CONTROLLED STUDY; COUGHING; ENDOTRACHEAL INTUBATION; FEMALE; HUMAN; HYPERALGESIA; INTRAOPERATIVE PERIOD; LOW DRUG DOSE; MALE; MEDICAL INSTRUMENTATION; MORPHINE TOLERANCE; PAIN ASSESSMENT; PATIENT CONTROLLED ANALGESIA; PEDIATRIC ANESTHESIA; PEDIATRIC SURGERY; POSTOPERATIVE ANALGESIA; POSTOPERATIVE NAUSEA; POSTOPERATIVE PAIN; PRIORITY JOURNAL; PRURITUS; RECOVERY ROOM; SCHOOL CHILD; SCOLIOSIS; SEDATION; SPINE SURGERY; SYRINGE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DOUBLE BLIND PROCEDURE; DRUG TOLERANCE; PEROPERATIVE CARE; RANDOMIZED CONTROLLED TRIAL;

ADOLESCENT; ANALGESIA, PATIENT-CONTROLLED; ANALGESICS; ANALGESICS, OPIOID; ANESTHETICS, INTRAVENOUS; CHILD; DOUBLE-BLIND METHOD; DRUG TOLERANCE; FEMALE; HUMANS; INTRAOPERATIVE CARE; KETAMINE; MALE; MORPHINE; PAIN, POSTOPERATIVE; PIPERIDINES; SCOLIOSIS;

EID: 53449086520     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/ane.0b013e318183919e     Document Type: Article

References (35)

1. Gibson PR. Anaesthesia for correction of scoliosis in children. Anaesth Intensive Care 2004;32:548-59
2. Kalkman CJ, Drummond JC, Ribberink AA. Low concentrations of isoflurane abolish motor evoked responses to transcranial electrical stimulation during nitrous oxide/opioid anesthesia in humans. Anesth Analg 1991;73:410-5
3. Sekimoto K, Nishikawa K, Ishizeki J, Kubo K, Saito S, Goto F. The effects of volatile anesthetics on intraoperative monitoring of myogenic motor-evoked potential to transcranial electrical stimulation and on partial neuromuscular blockade during propofol/fentanyl/nitrous oxide anesthesia in humans. J Neurosurg Anesthesiol 2006;18:106-11
4. Crawford MW, Hickey C, Zaarour C, Howard A, Naser B. Development of acute opioid tolerance during infusion of remifentanil for pediatric scoliosis surgery. Anesth Analg 2006;102:1662-7
5. Kissin I, Bright C, Bradley L. Acute tolerance to continuously infused alfentanil: the role of cholecystokinin and N-methyl-daspartate- nitric oxide systems. Anesth Analg 2000;91:110-6
6. Guignard B, Bossard AE, Coste C, Sessler DI, Lebrault C, Alfonsi P, Fletcher D, Chauvin M. Acute opioid tolerance: Intraoperative remifentanil increases postoperative pain and morphine requirement. Anesthesiolology 2000;93:409-7
7. Vinik HR, Kissin I. Rapid development of tolerance to analgesia during remifentanil infusion in humans. Anesth Analg 1998;86:1307-11
8. Kissin I, Lee SS, Arthur GR, Bradley EL Jr. Time course characteristics of acute tolerance development to continuously infused alfentanil in rats. Anesth Analg 1996;83:600-5
9. Kissin I, Brown PT, Robinson CA, Bradley EL Jr. Acute tolerance in morphine analgesia: continuous infusion and single injection in rats. Anesthesiology 1991;74:166-71
10. Jordan B, Devi LA. Molecular mechanisms of opioid receptor signal transduction. Br J Anaesth 1998;81:12-9
11. Trafton JA, Abbadie C, Marek K, Basbaum AI. Postsynaptic signaling via the -opioid receptor: responses of dorsal horn neurons to exogenous opioids and noxious stimulation. J Neurosci 2000;20:8578-84
12. Gardell LR, Wang R, Burgess SE, Ossipov MH, Vanderah TW, Malan TP, Lai J, Porreca F. Sustained morphine exposure induces a spinal dynorphin-dependent enhancement of excitatory transmitter release from primary afferent fibers. J Neurosci 2002;22:6747-55
13. Borgland SL. Acute opioid receptor desensitization and tolerance: is there a link? Clin Exp Pharmacol Physiol 2001;28:147-54
14. Guitart X, Nestler EJ. Second messenger and protein phosphorylation mechanisms underlying opiate addiction: studies in the rat locus coeruleus. Neurochem Res 1993;18:5-13
15. Shimoyama N, Shimoyama M, Inturrisi CE, Elliot KJ. Ketamine attenuates and reverses morphine tolerance in rodents. Anesthesiology 1996;85:1357-66
16. McCarthy RJ, Kroin JS, Tuman KJ, Penn RD, Ivankovich AD. Antinociceptive potentiation and attenuation of tolerance by intrathecal co-infusion of magnesium sulfate and morphine in rats. Anesth Analg 1998;86:830-6
17. Laulin J, Maurette P, Corcuff J, Rivat C, Chauvin M, Simonnet G. The role of ketamine in preventing fentanyl-induced hyperalgesia and subsequent acute morphine tolerance. Anesth Analg 2002;94:1263-9
18. Park K, Max M, Robinovitz E, Gracely R, Bennett G. Effects of intravenous ketamine, alfentanil, or placebo on pain, pinprick hyperalgesia, and allodynia produced by intradermal capsaicin in human subjects. Pain 1995;63:163-72
19. Stubhaug A, Breivik H, Eide PK, Kreunen M, Foss A. Mapping of punctuate hyperalgesia around a surgical incision demonstrates that ketamine is a powerful suppressor of central sensitization to pain following surgery. Acta Anaesthesiol Scand 1997;41:1124-32
20. Finck DA, Samaniego E, Ngai SH. Morphine tolerance decreases the analgesic effects of ketamine in mice. Anesthesiology 1988;68:397-400
21. Smith DJ, Pekoe GM, Martin LL, Coalgate B. The interaction of ketamine with the opiate receptor. Life Sci 1980;26:789-95
22. Mikkelsen S, Ilkjaer S, Brennum J, Borgbjerg FM, Dahl JB. The effect of naloxone on ketamine-induced effects on hyperalgesia and ketamine-induced side effects in humans. Anesthesiology 1999;90:1539-45
23. Fu E, Miguel R, Scharf J. Preemptive ketamine decreases postoperative narcotic requirements in patients undergoing abdominal surgery. Anesth Analg 1997;84:1086-90
24. De Kock M, Lavand'homme P, Waterloos H. Balanced analgesia in the perioperative period: is there a place for ketamine? Pain 2001;92:373-80
25. Guillou N, Tanguy M, Seguin P, Branger B, Campion J, Malledant Y. The effects of small-dose ketamine on morphine consumption in surgical intensive care unit patients after major abdominal surgery. Anesth Analg 2003;97:843-7
26. Guignard B, Coste C, Costes H, Sessler D, Lebrault C, Morris W, Simonnet G, Chauvin M. Supplementing desfluraneremifentanil anesthesia with small-dose ketamine reduces perioperative opioid analgesic requirements. Anesth Analg 2002;95:103-8
27. Joly V, Richebe P, Guignard B, Fletcher D, Maurette P, Sessler DI, Chauvin M. Remifentanil-induced postoperative hyperalgesia and its prevention with small-dose ketamine. Anesthesiology 2005;103:147-55
28. McCartney C, Sinha A, Katz J. A qualitative systematic review of the role of N-methyl-D-aspartate anatgonists in preventative analgesia. Anesth Analg 2004;98:1385-400
29. Ganne O, Abisseror M, Menault P, Malhie're S, Chambost V, Charpiat B, Ganne C, Viale JP. Low-dose ketamine failed to spare morphine after a remifentanil-based anaesthesia for ear, nose and throat surgery. Eur J Anaesthesiol 2005;22:426-30
30. Schmid R, Sandler A, Katz J. Use and efficacy of low-dose ketamine in the management of acute postoperative pain: a review of current techniques and outcomes. Pain 1999;82:111-25
31. Bowdle T, Radant A, Cowley D, Kharasch E, Strassman R, Roy-Byrne P. Psychedelic effects of ketamine in healthy volunteers: relationship to steady-state plasma concentrations. Anesthesiology 1998;88:82-8
32. Mazoit JX. Pharmacokinetic/pharmacodynamic modeling of anesthetics in children. Pediatr Drugs 2006;8:139-50
33. Englelhardt T, Macdonald J, Galley HF, Webster NR. Selective phosphodiesterase 5 inhibition does not reduce propofol sedation requirements but affects speed of recovery and plasma cyclic GMP concentrations in healthy volunteers. Anesth Analg 2005;101:1050-3
34. Gonzales JM, Loeb AL, Reichard PS, Irvine S. Ketamine inhibits glutamate-, N-methyl-D-aspartate-, and quisqualate-stimulated cGMP production in cultured cerebral neurons. Anesthesiology 1995;82:205-13
35. Englelhardt T, Lowe PR, Galley HF, Webster NR. Inhibition of neuronal nitric oxide synthase reduces the propofol requirements in wild-type and nNOS knockout mice. Eur J Anaesthesiol 2006;23:197-201