-
1
-
-
0025826161
-
Oskar organizes the germ plasm and directs localization of the posterior determinant nanos
-
Ephrussi A., Dickinson L.K., and Lehmann R. Oskar organizes the germ plasm and directs localization of the posterior determinant nanos. Cell 66 (1991) 37-50
-
(1991)
Cell
, vol.66
, pp. 37-50
-
-
Ephrussi, A.1
Dickinson, L.K.2
Lehmann, R.3
-
2
-
-
0035206539
-
RNA localization and germ cell determination in Xenopus
-
Kloc M., Bilinski S., Chan A.P., Allen L.H., Zearfoss N.R., and Etkin L.D. RNA localization and germ cell determination in Xenopus. Int Rev Cytol 203 (2001) 63-91
-
(2001)
Int Rev Cytol
, vol.203
, pp. 63-91
-
-
Kloc, M.1
Bilinski, S.2
Chan, A.P.3
Allen, L.H.4
Zearfoss, N.R.5
Etkin, L.D.6
-
3
-
-
0031891129
-
Germ plasm in Caenorhabditis elegans, Drosophila and Xenopus
-
Ikenishi K. Germ plasm in Caenorhabditis elegans, Drosophila and Xenopus. Dev Growth Differ 40 (1998) 1-10
-
(1998)
Dev Growth Differ
, vol.40
, pp. 1-10
-
-
Ikenishi, K.1
-
5
-
-
40149110698
-
X chromosome activity in mouse XX primordial germ cells
-
Chuva de Sousa Lopes S.M., Hayashi K., Shovlin T.C., Mifsud W., Surani M.A., and McLaren A. X chromosome activity in mouse XX primordial germ cells. PLoS Genet 4 (2008) e30
-
(2008)
PLoS Genet
, vol.4
-
-
Chuva de Sousa Lopes, S.M.1
Hayashi, K.2
Shovlin, T.C.3
Mifsud, W.4
Surani, M.A.5
McLaren, A.6
-
6
-
-
0033558165
-
Bmp4 is required for the generation of primordial germ cells in the mouse embryo [see comments]
-
Lawson K.A., Dunn N.R., Roelen B.A., Zeinstra L.M., Davis A.M., Wright C.V., Korving J.P., and Hogan B.L. Bmp4 is required for the generation of primordial germ cells in the mouse embryo [see comments]. Genes Dev 13 (1999) 424-436
-
(1999)
Genes Dev
, vol.13
, pp. 424-436
-
-
Lawson, K.A.1
Dunn, N.R.2
Roelen, B.A.3
Zeinstra, L.M.4
Davis, A.M.5
Wright, C.V.6
Korving, J.P.7
Hogan, B.L.8
-
7
-
-
0034465667
-
Requirement of Bmp8b for the generation of primordial germ cells in the mouse
-
Ying Y., Liu X.M., Marble A., Lawson K.A., and Zhao G.Q. Requirement of Bmp8b for the generation of primordial germ cells in the mouse. Mol Endocrinol 14 (2000) 1053-1063
-
(2000)
Mol Endocrinol
, vol.14
, pp. 1053-1063
-
-
Ying, Y.1
Liu, X.M.2
Marble, A.3
Lawson, K.A.4
Zhao, G.Q.5
-
8
-
-
0035871471
-
Cooperation of endoderm-derived BMP2 and extraembryonic ectoderm-derived BMP4 in primordial germ cell generation in the mouse
-
Ying Y., and Zhao G.Q. Cooperation of endoderm-derived BMP2 and extraembryonic ectoderm-derived BMP4 in primordial germ cell generation in the mouse. Dev Biol 232 (2001) 484-492
-
(2001)
Dev Biol
, vol.232
, pp. 484-492
-
-
Ying, Y.1
Zhao, G.Q.2
-
9
-
-
0037130207
-
A molecular programme for the specification of germ cell fate in mice
-
Saitou M., Barton S.C., and Surani M.A. A molecular programme for the specification of germ cell fate in mice. Nature 418 (2002) 293-300
-
(2002)
Nature
, vol.418
, pp. 293-300
-
-
Saitou, M.1
Barton, S.C.2
Surani, M.A.3
-
10
-
-
22444448587
-
Blimp1 is a critical determinant of the germ cell lineage in mice
-
This study revealed that the Blimp1-positive cells originating from the proximal posterior epiblast cells are indeed the lineage-restricted primordial germ cell precursors.
-
Ohinata Y., Payer B., O'Carroll D., Ancelin K., Ono Y., Sano M., Barton S.C., Obukhanych T., Nussenzweig M., Tarakhovsky A., et al. Blimp1 is a critical determinant of the germ cell lineage in mice. Nature 436 (2005) 207-213. This study revealed that the Blimp1-positive cells originating from the proximal posterior epiblast cells are indeed the lineage-restricted primordial germ cell precursors.
-
(2005)
Nature
, vol.436
, pp. 207-213
-
-
Ohinata, Y.1
Payer, B.2
O'Carroll, D.3
Ancelin, K.4
Ono, Y.5
Sano, M.6
Barton, S.C.7
Obukhanych, T.8
Nussenzweig, M.9
Tarakhovsky, A.10
-
11
-
-
33744795753
-
Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells
-
Ancelin K., Lange U.C., Hajkova P., Schneider R., Bannister A.J., Kouzarides T., and Surani M.A. Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells. Nat Cell Biol 8 (2006) 623-630
-
(2006)
Nat Cell Biol
, vol.8
, pp. 623-630
-
-
Ancelin, K.1
Lange, U.C.2
Hajkova, P.3
Schneider, R.4
Bannister, A.J.5
Kouzarides, T.6
Surani, M.A.7
-
12
-
-
34447522791
-
Cellular dynamics associated with the genome-wide epigenetic reprogramming in migrating primordial germ cells in mice
-
Seki Y., Yamaji M., Yabuta Y., Sano M., Shigeta M., Matsui Y., Saga Y., Tachibana M., Shinkai Y., and Saitou M. Cellular dynamics associated with the genome-wide epigenetic reprogramming in migrating primordial germ cells in mice. Development 134 (2007) 2627-2638
-
(2007)
Development
, vol.134
, pp. 2627-2638
-
-
Seki, Y.1
Yamaji, M.2
Yabuta, Y.3
Sano, M.4
Shigeta, M.5
Matsui, Y.6
Saga, Y.7
Tachibana, M.8
Shinkai, Y.9
Saitou, M.10
-
13
-
-
43449083748
-
Nanos3 maintains the germ cell lineage in the mouse by suppressing both Bax-dependent and -independent apoptotic pathways
-
Suzuki H., Tsuda M., Kiso M., and Saga Y. Nanos3 maintains the germ cell lineage in the mouse by suppressing both Bax-dependent and -independent apoptotic pathways. Dev Biol 318 (2008) 133-142
-
(2008)
Dev Biol
, vol.318
, pp. 133-142
-
-
Suzuki, H.1
Tsuda, M.2
Kiso, M.3
Saga, Y.4
-
14
-
-
0041821717
-
Conserved role of nanos proteins in germ cell development
-
Tsuda M., Sasaoka Y., Kiso M., Abe K., Haraguchi S., Kobayashi S., and Saga Y. Conserved role of nanos proteins in germ cell development. Science 301 (2003) 1239-1241
-
(2003)
Science
, vol.301
, pp. 1239-1241
-
-
Tsuda, M.1
Sasaoka, Y.2
Kiso, M.3
Abe, K.4
Haraguchi, S.5
Kobayashi, S.6
Saga, Y.7
-
15
-
-
27744551009
-
Structure and regulation of Kit protein-tyrosine kinase - the stem cell factor receptor
-
Roskoski Jr. R. Structure and regulation of Kit protein-tyrosine kinase - the stem cell factor receptor. Biochem Biophys Res Commun 338 (2005) 1307-1315
-
(2005)
Biochem Biophys Res Commun
, vol.338
, pp. 1307-1315
-
-
Roskoski Jr., R.1
-
16
-
-
25844507795
-
Signaling by Kit protein-tyrosine kinase - the stem cell factor receptor
-
Roskoski Jr. R. Signaling by Kit protein-tyrosine kinase - the stem cell factor receptor. Biochem Biophys Res Commun 337 (2005) 1-13
-
(2005)
Biochem Biophys Res Commun
, vol.337
, pp. 1-13
-
-
Roskoski Jr., R.1
-
17
-
-
0025027264
-
Embryonic expression of a haematopoietic growth factor encoded by the Sl locus and the ligand for c-kit
-
Matsui Y., Zsebo K.M., and Hogan B.L. Embryonic expression of a haematopoietic growth factor encoded by the Sl locus and the ligand for c-kit. Nature 347 (1990) 667-669
-
(1990)
Nature
, vol.347
, pp. 667-669
-
-
Matsui, Y.1
Zsebo, K.M.2
Hogan, B.L.3
-
18
-
-
0027812323
-
The kit-ligand (steel factor) and its receptor c-kit/W: pleiotropic roles in gametogenesis and melanogenesis
-
Besmer P., Manova K., Duttlinger R., Huang E.J., Packer A., Gyssler C., and Bachvarova R.F. The kit-ligand (steel factor) and its receptor c-kit/W: pleiotropic roles in gametogenesis and melanogenesis. Dev Suppl 119 (1993) 125-137
-
(1993)
Dev Suppl
, vol.119
, pp. 125-137
-
-
Besmer, P.1
Manova, K.2
Duttlinger, R.3
Huang, E.J.4
Packer, A.5
Gyssler, C.6
Bachvarova, R.F.7
-
19
-
-
0025741284
-
Requirement for mast cell growth factor for primordial germ cell survival in culture
-
Dolci S., Williams D.E., Ernst M.K., Resnick J.L., Brannan C.I., Lock L.F., Lyman S.D., Boswell H.S., and Donovan P.J. Requirement for mast cell growth factor for primordial germ cell survival in culture. Nature 352 (1991) 809-811
-
(1991)
Nature
, vol.352
, pp. 809-811
-
-
Dolci, S.1
Williams, D.E.2
Ernst, M.K.3
Resnick, J.L.4
Brannan, C.I.5
Lock, L.F.6
Lyman, S.D.7
Boswell, H.S.8
Donovan, P.J.9
-
20
-
-
0025779118
-
Effects of the steel gene product on mouse primordial germ cells in culture
-
Godin I., Deed R., Cooke J., Zsebo K., Dexter M., and Wylie C.C. Effects of the steel gene product on mouse primordial germ cells in culture. Nature 352 (1991) 807-809
-
(1991)
Nature
, vol.352
, pp. 807-809
-
-
Godin, I.1
Deed, R.2
Cooke, J.3
Zsebo, K.4
Dexter, M.5
Wylie, C.C.6
-
21
-
-
33846146040
-
Steel factor controls midline cell death of primordial germ cells and is essential for their normal proliferation and migration
-
Runyan C., Schaible K., Molyneaux K., Wang Z., Levin L., and Wylie C. Steel factor controls midline cell death of primordial germ cells and is essential for their normal proliferation and migration. Development 133 (2006) 4861-4869
-
(2006)
Development
, vol.133
, pp. 4861-4869
-
-
Runyan, C.1
Schaible, K.2
Molyneaux, K.3
Wang, Z.4
Levin, L.5
Wylie, C.6
-
22
-
-
34249883075
-
Chemoattractant action and molecular signaling pathways of Kit ligand on mouse primordial germ cells
-
This study revealed that Kit ligand functions as a PGC chemoattractant required for their directional migration.
-
Farini D., La Sala G., Tedesco M., and De Felici M. Chemoattractant action and molecular signaling pathways of Kit ligand on mouse primordial germ cells. Dev Biol 306 (2007) 572-583. This study revealed that Kit ligand functions as a PGC chemoattractant required for their directional migration.
-
(2007)
Dev Biol
, vol.306
, pp. 572-583
-
-
Farini, D.1
La Sala, G.2
Tedesco, M.3
De Felici, M.4
-
23
-
-
0021932945
-
A recessive mutation (ter) causing germ cell deficiency and a high incidence of congenital testicular teratomas in 129/Sv-ter mice
-
Noguchi T., and Noguchi M. A recessive mutation (ter) causing germ cell deficiency and a high incidence of congenital testicular teratomas in 129/Sv-ter mice. J Natl Cancer Inst 75 (1985) 385-392
-
(1985)
J Natl Cancer Inst
, vol.75
, pp. 385-392
-
-
Noguchi, T.1
Noguchi, M.2
-
24
-
-
0028450067
-
The ter primordial germ cell deficiency mutation maps near Grl-1 on mouse chromosome 18
-
Sakurai T., Katoh H., Moriwaki K., Noguchi T., and Noguchi M. The ter primordial germ cell deficiency mutation maps near Grl-1 on mouse chromosome 18. Mamm Genome 5 (1994) 333-336
-
(1994)
Mamm Genome
, vol.5
, pp. 333-336
-
-
Sakurai, T.1
Katoh, H.2
Moriwaki, K.3
Noguchi, T.4
Noguchi, M.5
-
25
-
-
19644373800
-
The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours
-
Youngren K.K., Coveney D., Peng X., Bhattacharya C., Schmidt L.S., Nickerson M.L., Lamb B.T., Deng J.M., Behringer R.R., Capel B., et al. The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours. Nature 435 (2005) 360-364
-
(2005)
Nature
, vol.435
, pp. 360-364
-
-
Youngren, K.K.1
Coveney, D.2
Peng, X.3
Bhattacharya, C.4
Schmidt, L.S.5
Nickerson, M.L.6
Lamb, B.T.7
Deng, J.M.8
Behringer, R.R.9
Capel, B.10
-
26
-
-
0042926721
-
Dead end, a novel vertebrate germ plasm component, is required for zebrafish primordial germ cell migration and survival
-
Weidinger G., Stebler J., Slanchev K., Dumstrei K., Wise C., Lovell-Badge R., Thisse C., Thisse B., and Raz E. Dead end, a novel vertebrate germ plasm component, is required for zebrafish primordial germ cell migration and survival. Curr Biol 13 (2003) 1429-1434
-
(2003)
Curr Biol
, vol.13
, pp. 1429-1434
-
-
Weidinger, G.1
Stebler, J.2
Slanchev, K.3
Dumstrei, K.4
Wise, C.5
Lovell-Badge, R.6
Thisse, C.7
Thisse, B.8
Raz, E.9
-
27
-
-
38349118916
-
RNA-binding protein Dnd1 inhibits microRNA access to target mRNA
-
This study demonstrates that the expression of dead end 1 (Dnd1) counteracts the function of several miRNAs in human cells and in primordial germ cells of zebrafish by binding mRNAs and prohibiting miRNAs from associating with their target sites.
-
Kedde M., Strasser M.J., Boldajipour B., Vrielink J.A., Slanchev K., le Sage C., Nagel R., Voorhoeve P.M., van Duijse J., Orom U.A., et al. RNA-binding protein Dnd1 inhibits microRNA access to target mRNA. Cell 131 (2007) 1273-1286. This study demonstrates that the expression of dead end 1 (Dnd1) counteracts the function of several miRNAs in human cells and in primordial germ cells of zebrafish by binding mRNAs and prohibiting miRNAs from associating with their target sites.
-
(2007)
Cell
, vol.131
, pp. 1273-1286
-
-
Kedde, M.1
Strasser, M.J.2
Boldajipour, B.3
Vrielink, J.A.4
Slanchev, K.5
le Sage, C.6
Nagel, R.7
Voorhoeve, P.M.8
van Duijse, J.9
Orom, U.A.10
-
28
-
-
33750619546
-
Differential regulation of germline mRNAs in soma and germ cells by zebrafish miR-430
-
Mishima Y., Giraldez A.J., Takeda Y., Fujiwara T., Sakamoto H., Schier A.F., and Inoue K. Differential regulation of germline mRNAs in soma and germ cells by zebrafish miR-430. Curr Biol 16 (2006) 2135-2142
-
(2006)
Curr Biol
, vol.16
, pp. 2135-2142
-
-
Mishima, Y.1
Giraldez, A.J.2
Takeda, Y.3
Fujiwara, T.4
Sakamoto, H.5
Schier, A.F.6
Inoue, K.7
-
29
-
-
33644521570
-
Retinoic acid regulates sex-specific timing of meiotic initiation in mice
-
This study is the first paper indicating that signaling by retinoic acid (RA) is required for meiotic initiation in embryonic ovaries. In addition, using specific inhibitors, they indicated that a cytochrome p450 from the 26 family (CYP26) is responsible for delaying meiotic initiation in embryonic testes.
-
Koubova J., Menke D.B., Zhou Q., Capel B., Griswold M.D., and Page D.C. Retinoic acid regulates sex-specific timing of meiotic initiation in mice. Proc Natl Acad Sci U S A 103 (2006) 2474-2479. This study is the first paper indicating that signaling by retinoic acid (RA) is required for meiotic initiation in embryonic ovaries. In addition, using specific inhibitors, they indicated that a cytochrome p450 from the 26 family (CYP26) is responsible for delaying meiotic initiation in embryonic testes.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 2474-2479
-
-
Koubova, J.1
Menke, D.B.2
Zhou, Q.3
Capel, B.4
Griswold, M.D.5
Page, D.C.6
-
30
-
-
39449131659
-
Nanos2 suppresses meiosis and promotes male germ cell differentiation
-
This study revealed that Nanos2, the male-specific RNA-binding protein suppresses meiotic initiation in embryonic male germ cells via suppressing stra8 expression and also functions to promote male germ cell program.
-
Suzuki A., and Saga Y. Nanos2 suppresses meiosis and promotes male germ cell differentiation. Genes Dev 22 (2008) 430-435. This study revealed that Nanos2, the male-specific RNA-binding protein suppresses meiotic initiation in embryonic male germ cells via suppressing stra8 expression and also functions to promote male germ cell program.
-
(2008)
Genes Dev
, vol.22
, pp. 430-435
-
-
Suzuki, A.1
Saga, Y.2
-
31
-
-
33751536886
-
In germ cells of mouse embryonic ovaries, the decision to enter meiosis precedes premeiotic DNA replication
-
This study revealed that Stra8 gene function is required for germ cells to undergo premeiotic DNA replication.
-
Baltus A.E., Menke D.B., Hu Y.C., Goodheart M.L., Carpenter A.E., de Rooij D.G., and Page D.C. In germ cells of mouse embryonic ovaries, the decision to enter meiosis precedes premeiotic DNA replication. Nat Genet 38 (2006) 1430-1434. This study revealed that Stra8 gene function is required for germ cells to undergo premeiotic DNA replication.
-
(2006)
Nat Genet
, vol.38
, pp. 1430-1434
-
-
Baltus, A.E.1
Menke, D.B.2
Hu, Y.C.3
Goodheart, M.L.4
Carpenter, A.E.5
de Rooij, D.G.6
Page, D.C.7
-
32
-
-
33646198340
-
Retinoid signaling determines germ cell fate in mice
-
This study revealed that meiosis is retarded in the fetal testis by the action of the retinoid-degrading enzyme Cyp26B1.
-
Bowles J., Knight D., Smith C., Wilhelm D., Richman J., Mamiya S., Yashiro K., Chawengsaksophak K., Wilson M.J., Rossant J., et al. Retinoid signaling determines germ cell fate in mice. Science 312 (2006) 596-600. This study revealed that meiosis is retarded in the fetal testis by the action of the retinoid-degrading enzyme Cyp26B1.
-
(2006)
Science
, vol.312
, pp. 596-600
-
-
Bowles, J.1
Knight, D.2
Smith, C.3
Wilhelm, D.4
Richman, J.5
Mamiya, S.6
Yashiro, K.7
Chawengsaksophak, K.8
Wilson, M.J.9
Rossant, J.10
-
33
-
-
34748870401
-
Apoptotic extinction of germ cells in testes of Cyp26b1 knockout mice
-
MacLean G., Li H., Metzger D., Chambon P., and Petkovich M. Apoptotic extinction of germ cells in testes of Cyp26b1 knockout mice. Endocrinology 148 (2007) 4560-4567
-
(2007)
Endocrinology
, vol.148
, pp. 4560-4567
-
-
MacLean, G.1
Li, H.2
Metzger, D.3
Chambon, P.4
Petkovich, M.5
-
34
-
-
29044432866
-
Dazl deficiency leads to embryonic arrest of germ cell development in XY C57BL/6 mice
-
Lin Y., and Page D.C. Dazl deficiency leads to embryonic arrest of germ cell development in XY C57BL/6 mice. Dev Biol 288 (2005) 309-316
-
(2005)
Dev Biol
, vol.288
, pp. 309-316
-
-
Lin, Y.1
Page, D.C.2
-
35
-
-
33750482567
-
Tdrd1/Mtr-1, a tudor-related gene, is essential for male germ-cell differentiation and nuage/germinal granule formation in mice
-
Chuma S., Hosokawa M., Kitamura K., Kasai S., Fujioka M., Hiyoshi M., Takamune K., Noce T., and Nakatsuji N. Tdrd1/Mtr-1, a tudor-related gene, is essential for male germ-cell differentiation and nuage/germinal granule formation in mice. Proc Natl Acad Sci U S A 103 (2006) 15894-15899
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 15894-15899
-
-
Chuma, S.1
Hosokawa, M.2
Kitamura, K.3
Kasai, S.4
Fujioka, M.5
Hiyoshi, M.6
Takamune, K.7
Noce, T.8
Nakatsuji, N.9
-
36
-
-
41649116098
-
DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes
-
Kuramochi-Miyagawa S., Watanabe T., Gotoh K., Totoki Y., Toyoda A., Ikawa M., Asada N., Kojima K., Yamaguchi Y., Ijiri T.W., et al. DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes. Genes Dev 22 (2008) 908-917
-
(2008)
Genes Dev
, vol.22
, pp. 908-917
-
-
Kuramochi-Miyagawa, S.1
Watanabe, T.2
Gotoh, K.3
Totoki, Y.4
Toyoda, A.5
Ikawa, M.6
Asada, N.7
Kojima, K.8
Yamaguchi, Y.9
Ijiri, T.W.10
-
37
-
-
34248580923
-
Translational control of maternal Cyclin B mRNA by Nanos in the Drosophila germline
-
Kadyrova L.Y., Habara Y., Lee T.H., and Wharton R.P. Translational control of maternal Cyclin B mRNA by Nanos in the Drosophila germline. Development 134 (2007) 1519-1527
-
(2007)
Development
, vol.134
, pp. 1519-1527
-
-
Kadyrova, L.Y.1
Habara, Y.2
Lee, T.H.3
Wharton, R.P.4
-
38
-
-
37849022712
-
Potential role of Nanos3 in maintaining the undifferentiated spermatogonia population
-
Lolicato F., Marino R., Paronetto M.P., Pellegrini M., Dolci S., Geremia R., and Grimaldi P. Potential role of Nanos3 in maintaining the undifferentiated spermatogonia population. Dev Biol 313 (2008) 725-738
-
(2008)
Dev Biol
, vol.313
, pp. 725-738
-
-
Lolicato, F.1
Marino, R.2
Paronetto, M.P.3
Pellegrini, M.4
Dolci, S.5
Geremia, R.6
Grimaldi, P.7
-
39
-
-
33846482690
-
Functional redundancy among Nanos proteins and a distinct role of Nanos2 during male germ cell development
-
Suzuki A., Tsuda M., and Saga Y. Functional redundancy among Nanos proteins and a distinct role of Nanos2 during male germ cell development. Development 134 (2007) 77-83
-
(2007)
Development
, vol.134
, pp. 77-83
-
-
Suzuki, A.1
Tsuda, M.2
Saga, Y.3
|