Analysis of the expression pattern of regulatory genes Pax6, Prox1, and Six3 during regeneration of eye structures in the newt

Biology Bulletin

Volumn 31, Issue 5, 2004, Pages 428-436

  Markitantova, Yu V ^a   Makar'ev, E O ^a   Smirnova, Yu A ^a   Zinov'eva, R D ^a   Mitashov, V I ^a  

^a KOL TSOV INSTITUTE OF DEVELOPMENTAL BIOLOGY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

EUKARYOTA; SALAMANDRIDAE; VERTEBRATA;

EID: 5344264480     PISSN: 10623590     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:BIBU.0000043766.41763.90     Document Type: Article

References (44)

1. Barthel, L.K. and Raymond, P.A., In situ Hybridization Studies of Retinal Neurons, Methods Enzymol., 2000, vol. 316, pp. 579-590.
2. Baumer, N., Marquardt, T., Stoykova, A., et al., Retinal Pigmented Epithelium Determination Requires the Redundant Activities of Pax2 and Pax6, Development, 2003, vol. 130, pp. 2903-2915.
3. Bene, F.D., Tessmar-Raible, K., and Wittbrodt, J., Direct Interaction of Geminin and Six3 in Eye Development, Nature, 2004, vol. 427, pp. 745-748.
4. Chow, R.L., Altman, C.R., Lang, R.A., and Hemmati-Brivanlou, A., Pax-6 Induces Ectopic Eyes in a Vertebrate, Development, 1999, vol. 126, pp. 4213-4222.
5. Dyer, M.A., Regulation of Proliferation, Cell Fate Specification and Differentiation by the Homeodomain Proteins Prox1, Six3, and Chx10 In the Developing Retins, Cell Cycle, 2003, vol. 2, no. 4, pp. 350-357.
6. Dyer, M.A., Livesey, F.J., Cepko, C.L., and Oliver, G., Prox1 Function Controls Progenitor Cell Proliferation and Horizontal Cell Genesis in the Mammalian Retina, Nature Gen., 2003, vol. 34, pp. 53-58.
7. Fuhrmann, S., Levine, E.M., and Reh, T.A., Extraocular Mesenchyme Patterns the Optic Vesicle during Early Eye Development in the Embryonic Chick, Development, 2000, vol. 127, p. 4599-1609.
8. Gehring, W.J., The Genetic Control of Eye Development and Its Implications for the Evolution of the Various Eye-types, Int. J. Dev. Biol., 2002, vol. 46, pp. 65-73.
9. Hatakeyama, J. and Kageyama, R., Retinal Cell Fate Determination and bHLH Factors, Seminars Cell Dev. Biol., 2004, vol. 15, pp. 83-89.
10. Hayashi, T., Yamagishi, A., Kuroiva, A., et al., Highly Efficient Transfection System for Functional Gene Analysis in Adult Amphibian Lens Regeneration, Develop. Growth Differ., 2001, vol. 43, pp. 361-370.
11. Hsieh, Y.W., Zhang, X.M., Lin., E., et al., The Homeobox Gene Six3 Is a Potential Regulator of Anterior Segment Formation in the Chick Eye, Dev. Biol., 2002, vol. 248, pp. 265-280.
12. Jung, J.C., Rio-Tsonis, K D., and Tsonis, P.A., Regulation of Homeobox-Containing Genes during Lens Regeneration, Exp. Eye Res., 1998, vol. 66, pp. 361-370.
13. Kammandel, B., Chowdhury, K., Stoykova, A., et al., Distinct cis-Elemential Modules Direct the Time-Space Pattern of the Pax6 Gene Activity, Dev. Biol., 1999, vol. 205, pp. 79-97.
14. Kaneko, Y., Matsumoto, G., and Hanyu, Y., Pax-6 Expression during Retinal Regeneration in the Adult Newt, Develop. Growth Differ., 1999, vol. 41, pp. 723-729.
15. Kaneko, Y., Hirota, K., Matsumo, G., and Hanyu, Y., Expression Pattern of a Newt Notch Homologue in Regenerating Newt Retina, Dev. Brain Res., 2001, vol. 128, pp. 53-62.
16. Kawakami, K., Sato, S., Ozaki, H., and Ikeda, K., Six Family Genes - Structure and Function as Transcription Factors and Their Roles in Development, BioEssays, 2000, vol. 22, pp. 616-626.
17. Keefe, J.R., An Analysis of Urodelian Retinal Regeneration. I. Studies of the Cellular Source of Retinal Regeneration in Notophthalmus viridescens Utilizing 3H-Thymidine and Colchicines, J. Exp. Zool., 1973, 84, pp. 185-205.
18. Lagutin, O., Zhu, C.C., Furuta, Y., et al., Six3 Promotes the Formation of Ectopic Optic Vesicle-like Structures in Mouse Embryos, Dev. Dynam., 2001, vol. 222, pp. 342-349.
19. Lengler, J. and Graw, J., Regulation of the Human Six3 Gene Promoter, Biochem. Biophys. Res. Commun., 2001, vol. 287, pp. 372-376.
20. Lengler, J., Rrausz, E., Tomarev, S., et al., Antagonistic Action of Six3 and Prox1 at the Gamma-Crystallin Promoter, Nucleic Acids Res., 2001, vol. 29, pp. 515-526.
21. Loosli, F., Winkler, S., and Wittbrodt, J., Six3 Overexpression Initiates the Formation of Ectopic Retina, Genes Dev., 1999, vol. 13, pp. 649-654.
22. Macdonald, R. and Wilson, S.W., Distribution of Pax6 Protein during Eye Development Suggest Discrete Roles in Proliferative and Differentiated Visual Cells, Dev. Genes Evol., 1997, vol. 206, pp. 363-369.
23. Makar'ev, E.O., Zinov'eva, R.D., and Mitashov, V.I., Expression of Regulatory Homeobox Genes during Retina Regeneration in Adult Newts, Izv. Akad. Nauk. Ser. Biol., 2002, no. 6, pp. 662-667.
24. Marquardt, T. and Gruss, P., Generating Neuronal Diversity in the Retina: One for Nearly All, Trends Neuroscience, 2002, vol. 25, no. 1, pp. 32-37.
25. Marquardt, T., Ashery-Padan, R., Andrejewsky, et al., Pax6 Is Required for the Multipotent State of Retinal Progenitor Cells, Cell, 2001, vol. 105, pp. 43-55.
26. Mitashov, V.I., Dynamics of DNA Biosynthesis in Pigment Epithelium during Eye Restitution after Surgical Removal of the Retina in Adult Pectinate Tritons, Tsitologiya, 1969, vol. 11, pp. 434-446.
27. Mitashov, V.I., Multipotent and Stem Cells in the Developing, Definitive, and Regenerating Vertebrate Eye, Izv. Akad. Nauk. Ser. Biol., 2001, no. 6, pp. 717-727.
28. Mitashov, V.I. and Koussulakos, S., Molecular Mechanisms of Development of the Eye Structures in Drosophila and Vertebrates, Ontogenez, 2001, vol. 32, pp. 14-28.
29. Mitashov, V.I., Koussoulakos, S., Zinovieva, R.D., et al., Constructive Synergism of Regulatory Genes Expressed in the Course of Eye and Muscle Development and Regeneration, Izv. Akad. Nauk. Ser. Biol., 2001, no. 3, pp. 245-259.
30. Mizuno, M., Takabatake, T., Takahashi, T.C., and Takashima, K., Pax6 Gene Expression in Newt Eye Development, Dev. Genes Evol., 1997, vol. 207, pp. 167-176.
31. Mizuno, N., Agata, K., Sawada, K., et al., Expression of Crystalline Genes in Embryonic and Regeneration Newt Lenses, Dev. Growth Differ., 2002, vol. 44, pp. 251-256.
32. Mochii, M., Ono, T., Matsubara, Y., and Eguchi, G., Spontaneous Transdifferentiation of Quail Pigmented Epithelial Cell Is Accompanied by a Mutation in the Mitf Gene, Dev. Biol., 1998, vol. 196, pp. 145-159.
33. Nishina, S., Kohsaka, Sh., Yamaguchi, Y., et al., Pax6 Expression in the Developing Human Eye, Br. J. Ophthalmol., 1999, vol. 83, pp. 723-727.
34. Perron, M., Boy, S., Amato, M.A., et al., A Novel Function for Hedgehog Signaling in Retinal Pigment Epithelium Differentiation, Development, 2003, vol. 130, pp. 1565-1577.
35. Rio-Tsonis, K.D., Washbaugh, C.H., and Tsonis, P.A., Expression of Pax-6 during Urodele Eye Development and Lens Regeneration, Proc. Natl. Acad. Sci. USA, 1995, vol. 92, pp. 5092-5096.
36. Rio-Tsonis, K.D., Jang, J.C., and Chiu, I.-M., and Tsonis, P.A., Conservation of Fibroblast Growth Factor Function in Lens Regeneration, Proc. Natl. Acad. Sci. USA, 1997, vol. 94, pp. 13701-13706.
37. Rio-Tsonis, K., Tomarev, S.I., and Tsonis, P.A., Regulation of Prox1 during Lens Regeneration, Invest. Ophthalmol. Vis. Sci., 1999, vol. 40, pp. 2039-2045.
38. Toy, J., Yang, J.M., Leppert, G.S., and Sundin, O.H., The Optix2 Homeobox Gene Is Expressed in Early Precursors of the Eye and Activates Retina-Specific Genes, Proc. Natl. Acad. Sci. USA, 1998, vol. 95, pp. 10643-10648.
39. Tressmar, K., Loosli, F., and Wittbrodt, J., A Screen for Co-Factors of Six3, Mech. Dev., 2002, vol. 117, pp. 103-113.
40. Tsonis, P.A., Tsavaris, M., Call, M.K., et al., Expression and Role of Retinoic Acid Receptor Alpha in Lens Regeneration, Develop. Growth Differ., 2002, vol. 44, pp. 391-394.
41. Wargelius, A., Seo, H.C., Austbo, L., and Fjose, A., Retinal Expression of Zebrafish Six3.1 and Its Regulation by Pax6, Biochem. Biophys. Res. Commun., 2003, vol. 309, pp. 475-481.
42. Zhang, X.M. and Yang, X.J., Temporal and Spatial Effects of Sonic Hedgehog Signaling in Chick Eye Morphogenesis, Dev. Biol., 2001, vol. 233, pp. 271-293.
43. Zhang, S.Sh., Fu, X.-Y., and Barnstable, C.J., Molecular Aspect of Vertebrate Retinal Development, Mol. Neurobiol., 2002, vol. 26, pp. 136-152.
44. Zuber, M.E., Gestri, G., Viczian, A.S., et al., Specification of the Vertebrate Eye by Network of Eye Field Transcription Factors, Development, 2003, vol. 130, pp. 5155-5167.