Pax9 is required for filiform papilla development and suppresses skin-specific differentiation of the mammalian tongue epithelium

Mechanisms of Development

Volumn 121, Issue 11, 2004, Pages 1313-1322

  Jonker, Leon ^a   Kist, Ralf ^a   Aw, Andrew ^a   Wappler, Ilka ^a   Peters, Heiko ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Epithelial differentiation; Filiform papillae; Keratin; Pax9; Tongue

Indexed keywords

HOXC13 PROTEIN; KERATIN; KRT2 1 PROTEIN; KRT2 17 PROTEIN; PROTEIN; TRANSCRIPTION FACTOR PAX9; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; DYSPLASIA; EPITHELIUM; GENOME; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ORGANOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN; TONGUE;

ANIMALS; CELL DIFFERENTIATION; CELL POLARITY; DOWN-REGULATION; EPITHELIUM; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; KERATINS; MICE; MICE, MUTANT STRAINS; MUTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PAIRED BOX TRANSCRIPTION FACTORS; SKIN; TONGUE; TRANSCRIPTION FACTORS;

MAMMALIA;

EID: 5344236034     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mod.2004.07.002     Document Type: Article

References (38)

1. B. Bloor, N. Tidman, I. Leigh, E. Odell, B. Dogan, and U. Wollina Expression of keratin K2e in cutaneous and oral lesions Am. J. Path. 162 2003 963 975
2. I. Cameron Cell proliferation, migration, and specialisation in the epithelium of the mouse tongue J. Exp. Zool. 163 1966 271 284
3. A. Cane, and R. Spearman The keratinised epithelium of the house mouse (Mus musculus) tongue: its structure and histochemistry Archs Oral. Biol. 14 1969 829 841
4. C. Collin, J. Ouhayoun, C. Grund, and W. Franke Suprabasal marker proteins distinguishing keratinizing squamous epithelia: cytokeratin 2 polypeptides of oral masticatory epithelium and epidermis are different Differentiation 51 1992 137 148
5. E. Dahl, E. Winterhager, O. Traub, and K. Willecke Expression of gap junction genes, connexin40 and connexin43 during fetal mouse development Anat. Embryol. 191 1995 267 278
6. D. Dhouailly, C. Xu, M. Manabe, A. Schermer, and T. Sun Expression of hair-related keratins in a soft epithelium: subpopulations of human and mouse dorsal tongue keratinocytes express keratin markers for hair-, skin- and esophagael-types of differentiation Exp. Cell Res. 181 1989 141 158
7. E. Fuchs, and S. Raghavan Getting under the skin of epidermal morphogenesis Nat. Rev. Genet. 3 2002 199 209
8. J. Gerber, T. Richter, E. Kremmer, J. Adamski, H. Hofler, R. Balling, and H. Peters Progressive loss of Pax9 expression correlates with increasing malignancy of dysplastic and cancerous epithelium of the human oesophagus J. Pathol. 197 2002 293 297
9. A. Godwin, and M. Capecchi HoxC13 mutant mice lack external hair Genes Dev. 12 1998 11 20
10. M. Hardman, S. Paraskevi, D. Banbury, and C. Byrne Patterned acquisition of skin barrier function during development Development (Cambridge, UK) 125 1998 1541 1552
11. H. Hennings, D. Michael, C. Cheng, P. Steinert, K. Holbrook, and S. Yuspa Calcium regulation of growth and differentiation of mouse epidermal cells in culture Cell 19 1980 245 254
12. F. Herzog, H. Winter, and J. Schweizer The large type II 70-kDa keratin of mouse epidermis is the ortholog of human keratin K2e Differentiation 102 1994 165 170
13. W. Hume, and C. Potten The ordered columnar structure of mouse filiform papillae J. Cell Sci. 22 1976 149 160
14. S. Iwasaki Evolution of the structure and function of the vertebrate tongue J. Anat. 201 2002 1 13
15. L. Jave-Suarez, H. Winter, L. Langbein, M. Rogers, and J. Schweizer HoxC13 is involved in the regulation of human hair keratin gene expression J. Biol. Chem. 277 2002 3718 3726
16. A. Kalinin, A. Kajava, and P. Steinert Epithelial barrier function: assembly and structural features of the cornified cell envelope Bioessays 24 2002 789 800
17. J. Kvedar, M. Manabe, S. Phillips, B. Ross, and H. Baden Characterization of sciellin, a precursor to the cornified envelope of human keratinocytes Differentiation 49 1992 195 204
18. L. Langbein, M. Rogers, H. Winter, S. Praetzel, and J. Schweizer The catalog of of human hair keratins J. Biol. Chem. 276 2001 35123 35132
19. D. Marshall, M. Hardman, and C. Byrne SPRR1 gene induction and barrier formation occur as coordinated moving fronts in terminally differentiating epithelia J. Invest. Dermat. 114 2000 967 975
20. D. Marshall, M. Hardman, K. Nield, and C. Byrne Differentially expressed late constituents of the epidermal cornified envelope Proc. Natl Acad. Sci. USA 98 2001 13031 13036
21. A. Mills, B. Zheng, X. Wang, H. Vogel, D. Roop, and A. Bradley p63 is a p53 homologue required for limb and epidermal morphogenesis Nature 398 1999 708 713
22. A. Neubuser, H. Koseki, and R. Balling Characterization and developmental expression of Pax9, a paired-box-containing gene related to Pax1 Dev. Biol. 170 1995 701 716
23. G. Park, S. Lim, S.-I. Jang, and M. Morasso Suprabasin, a novel epidermal differentiation marker and potential cornified envelope precursor J. Biol. Chem. 277 2002 45195 45202
24. H. Peters, and R. Balling Teeth. Where and how to make them Trends Genet. 15 1999 59 65
25. H. Peters, G. Schuster, A. Neubuser, T. Richter, H. Hofler, and R. Balling Isolation of the PAX9 cDNA from the human esophogus Mammal. Genome 8 1997 62 64
26. H. Peters, A. Neubuser, K. Kratochwil, and R. Balling Pax9-deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities Gen. Dev. 12 1998 2735 2747
27. J. Pispa, and I. Thesleff Mechanisms of ectodermal organogenesis Dev. Biol. 262 2003 195 205
28. M. Santos, A. Bravo, C. Lopez, J. Paramio, and J. Jorcano Severe abnormalities in the oral mucosa induced by suprabasal expression of epidermal keratin K10 in transgenic mice J. Biol. Chem. 277 2002 35371 35377
29. J. Segre, C. Bauer, and E. Fuchs Klf4 is a transcription factor required for establishing the barrier function of the skin Nat. Genet. 24 1999 356 360
30. P. Sharpe Neural crest and tooth morphogenesis Adv. Dent. Res. 15 2001 4 7
31. L. Smith, R. Underwood, and W. McLean Ontogeny and regional variability of keratin 2e (K2e) in developing human fetal skin: a unique spatial and temporal pattern of keratin expression in development B. J. Dermat. 140 1999 582 591
32. P. Steinert, E. Candi, T. Kartasova, and L. Marekov Small proline-rich proteins are cross-bridging proteins in the cornified cell envelopes of stratified squamous epithelia J. Struct. Biol. 122 1998 76 85
33. D. Stockton, P. Das, M. Goldenberg, R. D'Souza, and P. Patel Mutation of PAX9 is associated with oligodontia Nat. Genet. 24 2000 18 19
34. A. Tkatchenko, R. Visconti, L. Shang, T. Papenbrock, N. Pruett, and T. Ito Overexpression of Hoxc13 in differentiating keratinocytes results in downregulation of a novel hair keratin gene cluster and alopecia Development (Cambridge, UK) 128 2001 1547 1558
35. E. Tobiasch, H. Winter, and J. Schweizer Structural features and sites of expression of a new murine 65kD and 48kD hair-related keratin pair, associated with a special type of parakeratotic epithelial differentiation Differentiation 50 1992 163 178
36. A. Wang, D. Johnson, and M. MacLeod Molecular cloning and characterisation of a novel mouse epidermal differentiation gene and its promoter Genomics 73 2001 284 290
37. P. Wong, E. Colucci-Guyon, K. Takahashi, C. Gu, C. Babinet, and P. Coulombe Introducing a null mutation in the mouse K6alpha and K6beta genes reveals their essential structural role in the oral mucosa J. Cell Biol. 150 2000 921 928
38. A. Yang, R. Schweitzer, D. Sun, M. Kaghad, N. Walker, and R. Bronson p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development Nature 398 1999 714 718