Small proline-rich proteins are cross-bridging proteins in the cornified cell envelopes of stratified squamous epithelia

Journal of Structural Biology

Volumn 122, Issue 1-2, 1998, Pages 76-85

  Steinert, Peter M ^a   Candi, Eleonora ^a   Kartasova, Tonja ^a   Marekov, Lyuben ^a  

^a NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

Author keywords

Barrier function; Cornified cell envelope; Epidermis; Involucrin; Loricrin; Transglutaminases

Indexed keywords

INVOLUCRIN; LORICRIN; PROLINE; PROTEIN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; STRUCTURAL PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; HUMAN; HUMAN CELL; HUMAN TISSUE; KERATINOCYTE; PEPTIDE ANALYSIS; PREPUCE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN CROSS LINKING; PROTEIN DEGRADATION; PROTEIN DOMAIN; SQUAMOUS EPITHELIUM; STRATUM CORNEUM; STRUCTURE ACTIVITY RELATION; TISSUE SPECIFICITY;

EID: 0031664479     PISSN: 10478477     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsbi.1998.3957     Document Type: Article

References (36)

1. An G., Tesfaigzi J., Chuu Y. J., Wu R. Isolation and characterization of the human spr1 gene and its regulation of expression by phorbol ester and cyclic AMP. J. Biol. Chem. 268:1993;10977-10982.
2. Austin S. J., Fujimoto W., Marvin K. W., Vollberg T. M., Lorand L., Jetten A. M. Cloning and regulation of cornifin beta, a new member of the cornifin/spr family. Suppression by retinoic acid receptor-selective retinoids. J. Biol. Chem. 271:1996;3737-3742.
3. Candi E., Tarcsa E., DiGiovanna J. J., Compton J. G., Elias P. M., Marekov L. N., Steinert P. M. Identification of a highly conserved lysine residue on type II keratins which is essential for the structural coordination of keratin intermediate filaments and the cornified cell envelope through isopeptide crosslinking by transglutaminases. Proc. Natl. Acad. Sci. USA. 1998.
4. Candi E., Melino G., Pei G., Tarcsa E., Marekov L. N., Steinert P. M. Bacterially-expressed human loricrin: Biochemical, structural and transglutaminase substrate properties of the major epidermal cornified cell envelope structural protein. J. Biol. Chem. 270:1995;26382-26390.
5. Downing D. T., Stewart M. E., Wertz P. W., Strauss J. S. Lipids in the epidermis and sebaceous glands. Dermatology in General Medicine. 1993;McGraw-Hill, New York. p. 210-221.
6. Eckert R. L., Yaffe M. B., Crish J. F., Murthy S., Rorke E. A., Welter J. F. Involucrin-structure and role in envelope assembly. J. Invest. Dermatol. 100:1993;613-617.
7. Elias P. M. The stratum corneum revisited. J. Dermatol. 23:1996;756-758.
8. Fujimoto W., Nakanishi G., Arata J., Jetten A. M. Differential expression of human cornifin α and β in squamous differentiating epithelial tissues and several skin lesions. J. Invest. Dermatol. 108:1997;200-204.
9. Gibbs S., Fijneman R., Wiegant J., van Kessel A. G., van de Putte P., Backendorf C. Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline rich proteins. Genomics. 16:1993;630-637.
10. Greco M. A., Lorand L., Lane W. S., Baden H. P., Parameswaran K. N. P., Kvedar J. C. The pancornulins: A group of small proline-rich-related cornified envelope precursors with bifunctional crosslinking capabilities and isopeptide bond formation. J. Invest. Dermatol. 104:1995;204-210.
11. Greenberg C. S., Birckbichler P. J., Rice R. H. Transglutaminases: Multifunctional crosslinking enzymes that stabilize tissues. FASEB J. 5:1991;3071-3077.
12. Hohl D. Cornified cell envelope. Dermatologica. 180:1990;201-211.
13. Hohl D., Lichti U., Turner M. L., Roop D. R., Steinert P. M. Characterization of human loricrin: Structure and function of a new class of epidermal cell envelope proteins. J. Biol. Chem. 266:1991;6626-6636.
14. Hohl D., Ruf O. B., de Viragh P. A., Huber M., Detrisac C. J., Schnyder U. W., Roop D. R. Expression patterns of loricrin in various species and tissues. Differentiation. 54:1993;25-34.
15. Hohl D., de Viragh P. A., Amiguet-Barras F., Gibbs S., Backendorf C., Huber M. The small proline rich proteins constitute a multigene family of differentially regulated cornified cell envelope precursor proteins. J. Invest. Dermatol. 104:1995;902-909.
16. Huber M., Rettler I., Bernasconi K., Frenk E., Lavrijsen S. P. MS. P., Ponec M., Bon A., Lautenschlager S., Schoderer D. F., Hohl D. Mutations in keratinocyte transglutaminase in lamellar ichthyosis. Science. 267:1995;525-528.
17. Jarnik M., Kartasova T., Steinert P. M., Lichti U., Steven A. C. Differential expression and cell envelope incorporation of small proline rich protein 1 in different cornified epithelia. J. Cell Sci. 109:1996;1381-1391.
18. Kartasova T., van Muijen G., Pelt-Heerschap H., van de Putte P. Isolation, characterization, and UV-stimulated expression of two families of genes encoding polypeptides of related structure in human epidermal keratinocytes. Mol. Cell Biol. 8:1988;2195-2210.
19. Kartasova T., Parry D. A. DD. A., Steinert P. M. Modeling of small proline rich protein evolution and structure. J. Invest. Dermatol. 104:1995;611.
20. Kartasova T., Kohno Y., Koizumi H., Osada S., Huh N., Lichti U., Steinert P. M., Kuroki T. Sequence and expression patterns of mouse SPR1: Correlation of expression with epithelial function. J. Invest. Dermatol. 106:1996;294-304.
21. 8. Biochem. J. 271:1988;305-308.
22. Marvin K. W., George M. D., Fujimoto W., Saunders N. A., Bernacki S. H., Jetten A. M. Cornifin, a cross-linked envelope precursor in keratinocytes that is down-regulated by retinoids. Proc. Natl. Acad. Sci. USA. 89:1992;11026-11030.
23. Owens D. M., Zainal T. A., Jetten A. M., Smart R. C. Localization and expression of cornifin alpha/SPRR1 in mouse epidermis, anagen hair follicles, and skin neoplasms. J. Invest. Dermatol. 106:1996;647-654.
24. Reichert U., Michel S., Schmidt R. The cornified cell envelope: A key structure of terminally differentiating keratinocytes. Darmon M., Blumenberg M. Molecular Biology of the Skin. 1993;107-150 Academic Press, New York.
25. Robinson N. A., Lapec S., Welter J. F., Eckert R. L. S100A11, S100A10, annexin I, desmosomal proteins, small proline-rich proteins, plasminogen activator inhibitor-2, and involucrin are components of the cornified envelope of cultured human epidermal keratinocytes. J. Biol. Chem. 272:1997;12035-12046.
26. Russell L. J., DiGiovanna J. J., Hashem N., Rogers G. R., Steinert P. M., Compton J. G., Bale S. J. TGM1. Nature Genet. 9:1995;279-283.
27. Simon M. The epidermal cornified cell envelope and its precursors. Leigh I. M., Lane E., Watt F. M. The Keratinocyte Handbook. 1994;275-292 Cambridge Univ. Press, Cambridge.
28. Steinert P. M. A model for the hierarchical structure of the human epidermal cornified cell envelope. Cell Death Different. 2:1995;23-31.
29. Steinert P. M., Marekov L. N. The proteins elafin, filaggrin, keratin intermediate filaments, loricrin and SPRs are isodipeptide crosslinked components of the human epidermal cornified cell envelope. J. Biol. Chem. 270:1995;17702-17711.
30. Steinert P. M., Marekov L. N. Involucrin is an important early component in the assembly of the epidermal cornified cell envelope. J. Biol. Chem. 272:1997;2021-2030.
31. Steinert, P. M. Kartasova, T. Marekov, L. N. 1998.
32. Steven A. C., Steinert P. M. The protein composition of the cornified cell envelope. J. Cell Sci. 107:1994;693-700.
33. Swartzendruber D. C., Wertz P. W., Madison K. C., Downing D. T. Evidence that the corneocyte has a chemically bound lipid envelope. J. Invest. Dermatol. 88:1987;709-713.
34. Tarcsa E., Marekov L. N., Andreoli J. M., Idler W. W., Candi E., Chung S.-I., Steinert P. M. The fate of trichohyalin: Sequential post-translational modifications by peptidylarginine deiminase and transglutaminases. J. Biol. Chem. 272:1997;27893-27901.
35. Williams M. L., Elias P. M. Genetically transmitted, generalized disorders of cornification: the ichthyoses. Alper J. C. Dermatology Clinics. 1987;155-178 Saunders, Philadelphia.
36. Yoneda K., Steinert P. M. The over-expression of loricrin in transgenic mice produces a normal phenotype. Proc. Natl. Acad. Sci. USA. 90:1993;10754-10758.