Mercury accumulation and its distribution to metallothionein in mouse brain after sub-chronic pulse exposure to mercury vapor

Archives of Toxicology

Volumn 78, Issue 9, 2004, Pages 489-495

  Yasutake, A ^a   Sawada, M ^b   Shimada, A ^b   Satoh, M ^c   Tohyama, C ^d  

^a NATIONAL INSTITUTE FOR MINAMATA DISEASE   (Japan)

^b TOTTORI UNIVERSITY   (Japan)

^c GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^d NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIES   (Japan)

Author keywords

Brain; Gel chromatography; Mercury vapor; Metallothionein; Mice

Indexed keywords

MERCURY; METALLOTHEIONIN II; METALLOTHIONEIN; METALLOTHIONEIN I; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR DISORDER; BIOACCUMULATION; BRAIN; CONTROLLED STUDY; CYTOPLASM; GLIA CELL; HISTOCHEMISTRY; LONG TERM EXPOSURE; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN SYNTHESIS; WEIGHT REDUCTION; WILD TYPE;

ADMINISTRATION, INHALATION; ANIMALS; BRAIN; MERCURY; METALLOTHIONEIN; MICE; MICE, KNOCKOUT; TIME FACTORS; TISSUE DISTRIBUTION; VOLATILIZATION;

ANIMALIA;

EID: 5344224077     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-004-0572-1     Document Type: Article

References (30)

1. Cai L, Hammond RR, Cherian MG (1999) Metallothionein expression and radiation protection in primary human CNS cultures. Toxicol Sci 48[Suppl 1]:290-291
2. Chung RS, Vickers JC, Chuah MI, Eckhardt BL, West AK (2002) Metallothionein-III inhibits initial neurite formation in developing neurons as well as postinjury, regenerative neurite sprouting. Exp Neurol 178:1-12
3. Danscher G, Meller-Madsen B (1985) Silver amplification of mercury sulfide and selenide: a histochemical method for light and electron microscopic localization of mercury in tissue. J Histochem Cytochem 33:219-228
4. Ebadi M (1986) Characterization of a metallothionein-like protein in rat brain. Biol Trace Elem Res 11:101-116
5. Erickson JC, Sewell AK, Jensen LT, Winge DR, Palmiter RD (1994) Enhanced neurotrophic activity in Alzheimer's disease cortex is not associated with down-regulation of metallothionein-III (GIF). Brain Res 646:297-304
6. Hirayama K (1985) Effects of combined administration of thiol compounds and methylmercury chloride on mercury distribution in rats. Biochem Pharmacol 34:2030-2032
7. Hozumi I, Inuzuka T, Tsuji S (1998) Brain injury and growth inhibitory factor (GIF) - a minireview. Neurochem Res 23:319-328
8. Irie Y, Keung WM (2001) Metallothionein-III antagonizes the neurotoxic and neurotrophic effects of amyloid beta peptides. Biochim Biophys Res Commun 282:416-420
9. Irie Y, Keung WM (2003) Anti-amyloid beta activity of metallothionein-III is different from its neuronal growth inhibitory activity: structure-activity studies. Brain Res 960:228-234
10. Itoh M, Ebadi M, Swanson S (1983) The presence of zinc binding proteins in brain. J Neurochem 41:823-829
11. Kobayashi H, Uchida Y, Ihara Y, Nakajima K, Kohsaka S, Miyatake T and Tsuji S (1993) Molecular cloning of rat growth inhibitory factor cDNA and the expression in the central nervous system. Mol Brain Res 19:188-194
12. Kramer KK, Liu J, Choudhuri S, Klaassen CD (1996) Induction of metallothionein mRNA and protein in murine astrocyte cultures. Toxicol Appl Pharmacol 136:94-100
13. Lee JY, Kim JH, Palmiter RD, Koh JY (2003) Zinc released from metallothionein-iii may contribute to hippocampal CA1 and thalamic neuronal death following acute brain injury. Exp Neurol 184:337-347
14. Miyazaki I, Asanuma M, Higashi Y, Sogawa CA, Tanaka K, Ogawa N (2002) Age-related changes in expression of metallothionein-III n rat brain. Neurosci Res 43:323-333
15. Montoliu C, Monfort P, Carrasco J, Palacios O, Capdevila M, Hidalgo J, Felipo V (2000) Metallothionein-III prevents glutamate and nitric oxide neurotoxicity in primary cultures of cerebellar neurons. J Neurochem 75:266-273
16. Naganuma A, Satoh M, Imura N (1987) Prevention of lethal and renal toxicity of cis-diamminedichloroplatinum (II) by induction of metallothionein synthesis without compromising its antitumor activity in mice. Cancer Res 47:983-987
17. Nishimura N, Nishimura H, Ghaffar A, Tohyama C (1992) Localization of metallothionein in the brain of rat and mouse. J Histochem Cytochem 40:309-315
18. Ono S, Cai L, Cherian MG (1998) Effects of gamma radiation on levels of brain metallothionein and lipid peroxidation in transgenic mice. Radiation Res 150:52-57
19. Ono S, Cai L, Koropatnick J, Cherian MG (2000) Radiation exposure does not alter metallothionein III isoform expression in mouse brain. Biol Trace Elem Res 74:23-30
20. Pamphlett R, Waley P (1996) Uptake of inorganic mercury by the human brain. Acta Neuropathol 92:525-527
21. Palmiter RD, Findley SD, Whitmore TE and Durnam DM (1992) MT-III, a brain-specific member of the metallothionein gene family. Proc Natl Acad Sci U S A 89:6333-6337
22. Rising L, Vitarella D, Kimerberg HK and Aschner M (1995) Metallothionein induction in neonatal rat primary astrocyte cultures protects against methylmercury cytotoxicity. J Neurochem 65:1562-1568
23. Uchida Y, Takio K, Titani K, Ihara Y and Tomonaga M (1991) The growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like protein. Neuron 7:337-347
24. 0 exposure induces long-lived brain metallothionein. Arch Toxicol 72:187-191
25. Yasutake A, Satoh M, Tohyama C, Hirayama K (1999) Selective and simple quantification of metallothionein III in mouse brain. J Health Sci 45:222-225
26. 0-exposed rat brain. Arch Toxicol 77:12-16
27. Yoshida M, Satoh M, Shimada A, Yasutake A, Sumi Y, Tohyama C (1999a) Pulmonary toxicity caused by acute exposure to mercury vapor is enhanced in metallothionein-null mice. Life Sci 64:1861-1867
28. Yoshida M, Satoh M, Yasutake A, Shimada A, Sumi Y, Tohyama C (1999b) Distribution and retention of mercury in metallothionein-null mice after exposure to mercury vapor. Toxicology 139:129-136
29. You HJ, Oh DH, Choi CY, Lee DG, Hahm KS, Moon AR, Jeong HG (2002) Protective effect of metallothionein-III on DNA damage in response to reactive oxygen species. Biochim Biophys Acta 1573:33-38
30. Zheng H, Berman NE, Klaassen CD (1995) Chemical modulation of metallothionein I and III mRNA in mouse brain. Neurochem Int 27:43-58