Palmitoylation of stathmin family proteins domain A controls Golgi versus mitochondrial subcellular targeting

Biology of the Cell

Volumn 100, Issue 10, 2008, Pages 577-591

  Chauvin, Stéphanie ^a,b   Poulain, Fabienne E ^a,b   Ozon, Sylvie ^a,b   Sobel, André ^a,b  

^a INSTITUT DU FER À MOULIN   (France)

^b SORBONNE UNIVERSITÉ   (France)

Author keywords

Golgi; Mitochondria; Neuron; Palmitoylation; Stathmin family; Subcellular targeting

Indexed keywords

GREEN FLUORESCENT PROTEIN; MUTANT PROTEIN; STATHMIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BRAIN NERVE CELL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DROSOPHILA; EMBRYO; FEMALE; GOLGI COMPLEX; HELA CELL; HIPPOCAMPUS; HUMAN; HUMAN CELL; MEMBRANE VESICLE; METABOLIC REGULATION; MITOCHONDRION; NERVE CELL DIFFERENTIATION; NONHUMAN; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TARGETING; RAT; SIGNAL TRANSDUCTION;

EID: 53349177067     PISSN: 02484900     EISSN: None     Source Type: Journal    
DOI: 10.1042/BC20070119     Document Type: Article

References (36)

1. Charbaut, E., Curmi, P.A., Ozon, S., Lachkar, S., Redeker, V. and Sobel, A. (2001) Stathmin family proteins display specific molecular and tubulin binding properties. J. Biol. Chem. 276, 16146-16154
2. Charbaut, E., Chauvin, S., Enslen, H., Zamaroczy, S. and Sobel, A. (2005) Two separate motifs cooperate to target stathmin-related proteins to the Golgi complex. J. Cell Sci. 118, 2313-2323
3. Curmi, P.A., Andersen, S.S., Lachkar, S., Gavet, O., Karsenti, E., Knossow, M. and Sobel, A. (1997) The stathmin/tubulin interaction in vitro. J. Biol. Chem. 272, 25029-25036
4. Di Paolo, G., Lutjens, R., Osen-Sand, A., Sobel, A., Catsicas, S. and Grenningloh, G. (1997a) Differential distribution of stathmin and SCG10 in developing neurons in culture. J. Neurosci. Res. 50, 1000-1009
5. 2-terminal region. J. Biol. Chem. 272, 5175-5182
6. El-Husseini, A.D. and Bredt, D.S. (2002) Protein palmitoylation: a regulator of neuronal development and function. Nat. Rev. Neurosci. 3, 791-802
7. Fukata, M., Fukata, Y., Adesnik, H., Nicoll, R.A. and Bredt, D.S. (2004) Identification of PSD-95 palmitoylating enzymes. Neuron 44, 987-996
8. Gavet, O., Ozon, S., Manceau, V., Lawler, S., Curmi, R and Sobel, A. (1998) The stathmin phosphoprotein family: intracellular localization and effects on the microtubule network. J. Cell Sci. 111, 3333-3346
9. Gavet, O., El Messari, S., Ozon, S. and Sobel, A. (2002) Regulation and subcellular localization of the microtubule-destabilizing stathmin family phosphoproteins in cortical neurons. J. Neurosci. Res. 68, 535-550
10. Greka, A., Navarro, B., Oancea, E., Duggan, A. and Clapham, D.E. (2003) TRPC5 is a regulator of hippocampal neurite length and growth cone morphology. Nat. Neurosci. 6, 837-845
11. Grenningloh, G., Soehrman, S., Bondallaz, P., Ruchti, E. and Cadas, H. (2004) Role of the microtubule destabilizing proteins SCG10 and stathmin in neuronal growth. J. Neurobiol. 58, 60-69
12. Huang, K. and El-Husseini, A. (2005) Modulation of neuronal protein trafficking and function by palmitoylation. Curr. Opin. Neurobiol. 15, 527-535
13. Huang, K., Yanai, A., Kang, R., Arstikaitis, P, Singaraja, R.R., Metzler, M., Mullard, A., Haigh, B., Gauthier-Campbell, C., Gutekunst, C.A. et al. (2004) Huntingtin-interacting protein HIP14 is a palmitoyl transferase involved in palmitoylation and trafficking of multiple neuronal proteins. Neuron 44, 977-986
14. Jourdain, L., Curmi, P., Sobel, A., Pantaloni, D. and Carlier, M.F. (1997) Stathmin: a tubulin-sequestering protein which forms a ternary T2S complex with two tubulin molecules. Biochemistry 36, 10817-10821
15. Kanaani, J., El-Husseini, A.D., Aguilera-Moreno, A., Diacovo, J.M., Bradt, D.S. and Baekkeskov, S. (2002) A combination of three distinct trafficking signals mediates axonal targeting and presynaptic clustering of GAD65. J. Cell Biol. 158, 1229-1238
16. Kang, S.W., Shin, Y.J., Shim, Y.J., Jeong, S.Y., Park, I.S. and Min, B.H. (2005) Clusterin interacts with SCLIP (SCG10-like protein) and promotes neurite outgrowth of PC12 cells. Exp. Cell Res. 309, 305-315
17. Linder, M.E., Middleton, P., Hepler, J.R., Taussig, R., Gilman, A.G. and Mumby, S.M. (1993) Lipid modifications of G proteins: alpha subunits are palmitoylated. Proc. Natl. Acad. Sci. U.S.A. 90, 3675-3679
18. Liu, Z., Chatterjee, T.K. and Fisher, R.A. (2002) RGS6 interacts with SCG10 and promotes neuronal differentiation. Role of the G gamma subunit-like (GGL) domain of RGS6. J. Biol. Chem. 277, 37832-37839
19. Lutjens, R., Igarashi, M., Pellier, V., Blasey, H., Di Paolo, G., Ruchti, E., Pfulg, C., Staple, J.K., Catsicas, S. and Grenningloh, G. (2000) Localization and targeting of SCG10 to the trans-Golgi apparatus and growth cone vesicles. Eur. J. Neurosci. 12, 2224-2234
20. Morii, H., Yamada, T., Nakano, I., Coulson, J.M. and Mori, N. (2005) Site-specific phosphorylation of SCG10 in neuronal plasticity: role of Ser73 phosphorylation by N-methyl D-aspartic acid receptor activation in rat hippocampus. Neurosci. Lett. 396, 241-246
21. Ng, D.C., Lin, B.H., Lim, C.P., Huang, G., Zhang, T, Poli, V. and Cao, X. (2006) Stat3 regulates microtubules by antagonizing the depolymerization activity of stathmin. J. Cell Biol. 172, 245-257
22. Nixon, A.B. and Casey, P.J. (2004) Analysis of the regulation of microtubule dynamics by interaction of RGSZ1 (RGS20) with the neuronal stathmin, SCG10. Methods Enzymol. 390, 53-64
23. Ohno, Y., Kihara, A., Sano, T and Igarashi, Y. (2006) Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins. Biochim. Biophys. Acta 1761, 474-483
24. Ozon, S., Maucuer, A. and Sobel, A. (1997) The stathmin family - molecular and biological characterization of novel mammalian proteins expressed in the nervous system. Eur. J. Biochem. 248, 794-806
25. Ozon, S., Byk, T. and Sobel, A. (1998) SCLIP: a novel SCG10-like protein of the stathmin family expressed in the nervous system. J. Neurochem. 70, 2386-2396
26. Ozon, S., Guichet, A., Gavet, O., Roth, S. and Sobel, A. (2002) Drosophila stathmin: a microtubule-destabilizing factor involved in nervous system formation. Mol. Biol. Cell 13, 698-710
27. Peters, A., Palay, S. and Websters, H. (1991) The Fine Structure of the Nervous System: The Neurons and Supporting Cells, Oxford University Press, New York
28. Poulain, F.E. and Sobel, A. (2007) The 'SCG10-Like Protein'SCLIP is a novel regulator of axonal branching in hippocampal neurons, unlike SCG10. Mol. Cell Neurosci. 34, 137-146
29. Ruthel, G. and Hollenbeck, P.J. (2003) Response of mitochondrial traffic to axon determination and differential branch growth. J. Neurosci. 23, 8618-8624
30. Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory Press, Plainview, NY
31. Skene, J.H. and Virag, I. (1989) Posttranslational membrane attachment and dynamic fatty acylation of a neuronal growth cone protein, GAP-43. J. Cell Biol. 108, 613-624
32. Smotrys, J.E. and Linder, M.E. (2004) Palmitoylation of intracellular signaling proteins: regulation and function. Annu. Rev. Biochem. 73, 559-587
33. Sudo, Y., Valenzuela, D., Beck-Sickinger, A.G., Fishman, M.C. and Strittmatter, S.M. (1992) Palmitoylation alters protein activity: blockade of G(o) stimulation by GAP-43. EMBO J. 11, 2095-2102
34. Togano, T., Kurachi, M., Watanabe, M., Grenningloh, G. and Igarashi, M. (2005) Role of Ser50 phosphorylation in SCG10 regulation of microtubule depolymerization. J. Neurosci. Res. 80, 475-480
35. - channel Kv1.4. Neuron 20, 125-134
36. Wedegaertner, P.B., Chu, D.H., Wilson, P.T., Levis, M.J. and Bourne, H.R. (1993) Palmitoylation is required for signalling functions and membrane attachment of Gq alpha and Gs alpha. J. Biol. Chem. 268, 25001-25008