The culture of zygotes to the blastocyst stage changes the postnatal expression of an epigentically labile allele, agouti viable yellow, in mice

Biology of Reproduction

Volumn 79, Issue 4, 2008, Pages 618-623

  Morgan, Hugh D ^a   Jin, Xing L ^a   Li, Aiqing ^a   Whitelaw, Emma ^c   O'Neill, Chris ^a,b,d  

^a ROYAL NORTH SHORE HOSPITAL   (Australia)

^b University of Sydney   (Australia)

^c QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^d UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Early development; Embryo; Environment; Epigenetic modification; Epigenetics; Gene regulation; In vitro embryo culture; Phenotypic variation; Preimplantation development

Indexed keywords

AGOUTI PROTEIN; PROTEIN AGOUTI VIABLE YELLOW; UNCLASSIFIED DRUG;

ALLELE; ANIMAL EXPERIMENT; ARTICLE; BLASTOCYST; CONTROLLED STUDY; DEVELOPMENTAL STAGE; EMBRYO; EMBRYO CULTURE; EMBRYO DEVELOPMENT; EMBRYO TRANSFER; EPIGENETICS; FEMALE; FERTILIZATION IN VITRO; MALE; MATING; MOUSE; NIDATION; NONHUMAN; OVULATION; PERINATAL PERIOD; PHENOTYPE; PREGNANCY; PREIMPLANTATION EMBRYO; PRIORITY JOURNAL; PUP (RODENT); ZYGOTE;

AGOUTI SIGNALING PROTEIN; ALLELES; ANIMALS; ANIMALS, NEWBORN; BLASTOCYST; EMBRYO CULTURE TECHNIQUES; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MALE; MICE; MICE, INBRED C57BL; MUTANT PROTEINS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; ZYGOTE;

AGOUTI; MUS;

EID: 53349143541     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod.108.068213     Document Type: Article

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