Effects of konjac glucomannan hydrolysates on the gut microflora of mice

Nutrition and Food Science

Volumn 38, Issue 5, 2008, Pages 422-429

  Elamir, Abdulmnem A ^a   Tester, Richard F ^b   Al Ghazzewi, Farage H ^b   Kaal, Hakim Y ^a   Ghalbon, Amna A ^a   Elmegrahai, Najat A ^a   Piggott, John R ^c  

^a UNIVERSITY OF TRIPOLI   (Libyan Arab Jamahiriya)

^b GLASGOW CALEDONIAN UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

Bacteria; Food products

Indexed keywords

BACTERIA (MICROORGANISMS); CLOSTRIDIUM PERFRINGENS; ESCHERICHIA COLI; LACTOBACILLUS; MUS;

EID: 53249147448     PISSN: 00346659     EISSN: None     Source Type: Journal    
DOI: 10.1108/00346650810906930     Document Type: Article

References (30)

1. Al-Ghazzewi, F.H., Khanna, S., Tester, R.F. and Piggott, J. (2007), "The potential use of konjac glucomannan hydrolysate as a prebiotic", Journal of the Science of Food and Agriculture, Vol. 87, pp. 1758-66.
2. Arjmandi, B.H., Ahn, J., Nathani, S. and Reeves, R.D. (1992), "Dietary soluble fibre and cholesterol affect serum cholesterol concentration, hepatic portal venous short-chain fatty acid concentrations and faecal sterol excretion in rats", Journal of Nutrition, Vol. 122, pp. 246-53.
3. Arvill, A. and Bodin, L. (1995), "Effect of short-term ingesion of konjac glucomannan on serum cholesterol in healthy men", American Journal of Clinical Nutrition, Vol. 61, pp. 585-9.
4. Buddington, K.K., Donahoo, J.B. and Buddington, R.K. (2002), "Dietary oligofructose and inulin protect mice from enteric and systemic pathogens and tumour inducers", Journal of Nutrition, Vol. 132, pp. 472-7.
5. Campbell, J.M., Fahey, G.C. and Wolf, B.W. (1997), "Selected indigestible oligosaccharides affect large bowel mass, caecal and faecal short-chain fatty acids, pH and microflora in rats", Journal of Nutrition, Vol. 127, pp. 130-6.
6. Chen, H.L., Fan, Y.H., Chen, M.E. and Chan, Y. (2005), "Unhydrolysed and hydrolysed konjac glucomannans modulated caecal and faecal microflora in Balb/c mice", Nutrition, Vol. 21, pp. 1059-64.
7. Chen, H.L., Sheu, W.h., Tai, T.S., Liaw, Y.P. and Chen, Y.C. (2003), "Konjac supplement alleviated hyper-cholesterolemia and hyperglycemia in type 2 diabetic subjects - a randomised double-blind trial", Journal of the American College of Nutrition, Vol. 22, pp. 36-42.
8. Dvorak, R.A. and Jacques, K.A. (1997), "Effect of adding mannan oligosaccharide (BioMos) to the milk replacer for calves", Journal of Animal Science, Vol. 75, Supplement 1, p. 22.
9. Gallaher, D.D., Gallaher, C.M., Mahrt, G.J., Carr, T.P., Hollingshead, C.H., Hesslink, R. and Wise, J. (2002), "A glucomannan and chitosan fibre supplement decreases plasma cholesterol and increases cholesterol excretion in overweight normocholesterolemic humans", Journal of the American College of Nutrition, Vol. 2, pp. 428-33.
10. Gibson, G.R. and Roberfroid, M.B. (1995), "Dietary modulation of the human colonic microbiota: Introducing the concept of prebiotics", Journal of Nutrition, Vol. 125, pp. 1401-12.
11. Gibson, G.R., McCartney, A.L. and Rastall, R.A. (2005), "Prebiotics and resistance to gastrointestinal infections", British Journal of Nutrition, Vol. 93, pp. S31-4.
12. Heinrichs, A.J., Jones, C.M. and Heinrichs, B.S. (2003), "Effects of mannan oligosaccharide or antibiotics in neonatal diets on health and growth of dairy calves", Journal of Dairy Science, Vol. 86, pp. 4064-9.
13. Hundemer, J.K., Nabar, S.P., Shriver, B.J. and Forman, L.P. (1991), "Dietary fibre sources lower blood cholesterol in C57BL/6 mice", Journal of Nutrition, Vol. 121, pp. 1360-5.
14. Jones, P.J. (2002), "Clinical nutrition: 7. Functional foods - more than just nutrition", Canadian Medical Association Journal, Vol. 166, pp. 1555-63.
15. Khanna, S. (2003), "The chemical, physical and nutritional properties of the plant polysaccharide konjac glucomannan", PhD thesis, Glasgow Caledonian University, Glasgow.
16. Kitamoto, N., Kato, Y., Ohnaka, T., Yokota, M., Tanaka, T. and Tsuji, K. (2003), "Bactericidal effects of konjac fluid on several food-poisoning bacteria", Journal of Food Protection, Vol. 66, pp. 1822-31.
17. Loening-Baucke, V., Miele, E. and Staiano, A. (2004), "Fiber (glucomannan) is beneficial in the treatment of childhood constipation", Pediatrics, Vol. 113, pp. E259-64.
18. Luo, D.Y. (1992), "Inhibitory effect of refined Amorphophallus konjac on MNNG-induced lung cancers in mice", Zhonghua Zhong Liu Za Zhi, Vol. 14, pp. 48-50.
19. Manning, T.S. and Gibson, G.R. (2004), "Prebiotics", Best Practice & Research Clinical Gastroenterology, Vol. 18, pp. 287-98.
20. Martino, F., Martino, E., Morrone, F., Carnevali, E., Forcone, R. and Niglio, T. (2005), "Effect of dietary supplementation with glucomannan on plasma total cholesterol and low density lipoprotein cholesterol in hypercholesterolemic children", Nutrition, Metabolism & Cardiovascular Diseases, Vol. 15, pp. 174-80.
21. Matsuura, Y. (1998), "Degradation of konjac glucomannan by enzymes in human faeces and formation if short-chain fatty acids by intestinal anaerobic bacteria", Journal of Nutritional Science and Vitaminology, Vol. 44, pp. 423-36.
22. Passaretti, S., Franzoni, M., Comin, U., Donzelli, R., Rocca, F., Colombo, E., Ferrara, A., Dinelli, M., Prada, A. and Curzio, M. (1991), "Action of glucomannans on complaints in patients affected with chronic constipation: A multicentric clinical evaluation", Italian Journal of Gastroenterology, Vol. 23, pp. 421-5.
23. Petrovsky, N. (2006), "Novel human polysaccharide adjuvants with dual Th1 and Th2 potentiating activity", Vaccine, Vol. 24, Supplement 2, pp. 26-9.
24. Pool-Zobel, B.L. (2005), "Inulin-type fructans and reduction in colon cancer risk: Review of experimental and human data", British Journal of Nutrition, Vol. 93, Supplement 1, pp. 73-90.
25. Rastall, R.A. (2004), "Bacteria in the gut: Friends and foes and how to alter the balance", Journal of Nutrition, Vol. 134, pp. S2022-6.
26. Takao, I., Fujii, S., Ishii, A., Han, L.K., Kumao, T., Ozaki, K. and Asakawa, A. (2006), "Effects of mannooligosaccharides from coffee mannan on fat storage in mice fed a high fat diet", Journal of Health Science, Vol. 52, pp. 333-7.
27. Walsh, D.E., Yaghoubian, V. and Behforooz, A. (1984), "Effect of glucomannan on obese patients: A clinical study", International Journal of Obesity, Vol. 8, pp. 289-93.
28. Wong, J.M.W., de Souza, R., Kendall, C.W.C., Emam, A. and Jenkins, D.J.A. (2006), "Colonic health: Fermentation and short chain fatty acids", Journal of Clinical Gastroenterology, Vol. 40, pp. 235-43.
29. Zhang, Y., Xie, B. and Gan, X. (2005), "Advance in the applications of konjac glucomannan and its derivatives", Carbohydrate Polymers, Vol. 60, pp. 27-31.
30. Zhou, Y.Z. (1991), "Effects of Amorphophalus konjac on the serum-lipid level in rats with hypercholesterolemia", Zeitschrift Fur Llinische Medizin-ZKM, Vol. 46, pp. 1513-15.