Optimization strategies using response surface methodologies in high performance liquid chromatography

Journal of Liquid Chromatography and Related Technologies

Volumn 31, Issue 19, 2008, Pages 2893-2916

  Zhang, Yi Jun ^a   Gong, Wen Jun ^a   Zhang, Jia Ming ^a   Zhang, Yu Ping ^a   Wang, Shu Ming ^b   Wang, Li ^b   Xue, Hui Yong ^b  

^a HENAN INSTITUTE OF SCIENCE AND TECHNOLOGY   (China)

^b Beijing Kangbeide Pharmaceutical Development Company Limited   (China)

Author keywords

2 Methyl 4 nitroaniline; 2 Methyl 6 nitroaniline; Experimental design; High performance liquid chromatography; Response surface methodology

Indexed keywords

ANILINE; BODY FLUIDS; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; COLUMNS (STRUCTURAL); DESIGN; EXPERIMENTS; FLOW RATE; FORECASTING; GAS DYNAMIC LASERS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; ISOMERS; MATHEMATICAL MODELS; NITROGEN COMPOUNDS; OPTIMIZATION; PLANNING; SEPARATION; STATISTICAL METHODS; STATISTICS; STRATEGIC PLANNING; SURFACE PROPERTIES;

2-METHYL-4-NITROANILINE; 2-METHYL-6-NITROANILINE; EXPERIMENTAL DESIGN; RESPONSE SURFACE METHODOLOGY;

LIQUID CHROMATOGRAPHY;

2 METHYL 4 NITROANILINE; 2 METHYL 6 NITROANILINE; ANILINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMOMETRICS; EXPERIMENTAL DESIGN; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; RESPONSE SURFACE METHOD; SEPARATION TECHNIQUE;

EID: 53249137968     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826070802424493     Document Type: Article

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