Optimization of the separation of β-blockers by ion-pair capillary electrophoresis in non-aqueous media using univariate and multivariate approaches

Journal of Separation Science

Volumn 25, Issue 15-17, 2002, Pages 1087-1095

  Servais, Anne Catherine ^a   Fillet, Marianne ^a   Chiap, Patrice ^a   Abushoffa, Adel M ^a   Hubert, Philippe ^a   Crommen, Jacques ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

blockers; Ion pairing; Non aqueous capillary electrophoresis; Optimization

Indexed keywords

CAPILLARY TUBES; ELECTROLYTES; ELECTROPHORESIS; IONS; ORGANIC COMPOUNDS; SOLVENTS;

ION-PAIR FORMATION;

SEPARATION;

ACETONITRILE; ALCOHOL; ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETAXOLOL; CAMPHOR DERIVATIVE; ION; METHANOL; METOPROLOL TARTRATE; ORGANIC SOLVENT; SOTALOL;

AQUEOUS SOLUTION; ARTICLE; CAPILLARY ELECTROPHORESIS; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG SCREENING; DRUG SELECTIVITY; EXPERIMENTAL DESIGN; ION PAIR EXTRACTION; METHODOLOGY; MOLECULAR INTERACTION; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; PROCESS OPTIMIZATION; SEPARATION TECHNIQUE; STATISTICAL ANALYSIS;

DRYOBALANOPS;

EID: 0036929148     PISSN: 16159306     EISSN: None     Source Type: Journal    
DOI: 10.1002/1615-9314(20021101)25:15/17<1087::AID-JSSC1087>3.0.CO;2-A     Document Type: Article

References (27)

1. I. Bjornsdottir, J. Tjornelund, S.H. Hansen, J. Cap. Elec. 1996, 3, 83-87.
2. M.-L. Riekkola, S.K. Wiedmer, I.E. Valkó, H. Sirén, J. Chromatogr. A 1997, 792, 13-35.
3. K.D. Altria, S.M. Bryant, Chromatographia 1997, 46, 122-130.
4. A. Karbaum, T. Jira, Electrophoresis 1999, 20, 3396-3401.
5. M.-L. Riekkola, M. Jussila, S.P. Porras, I.E. Valkó, J. Chromatogr. A 2000, 892, 155-170.
6. F. Wang, M.G. Khaledi, J. Chromatogr. A 2000, 875, 277-293.
7. F. Steiner, M. Hassel, Electrophoresis 2000, 21, 3994-4016.
8. C. Pettersson, G. Schill, J. Chromatogr. A 1981, 204, 179-183.
9. J. Crommen, J. Pharm. Biomed. Anal. 1983, 1, 549-555.
10. J. Crommen, P. Herné, J. Pharm. Biomed. Anal. 1984, 2, 241-253.
11. C. Pettersson, J. Chromatogr. A 1984, 316, 553-567.
12. C. Pettersson, G. Schill, J. Liq. Chromatogr. 1986, 9 (2-3), 269-290.
13. J. Crommen, G. Schill, D. Westerlund, L. Hackzell, Chromatographia 1987, 24, 252-260.
14. E. Arvidsson, J. Crommen, G. Schill, D. Westerlund, Chromatographia 1987, 24, 460-468.
15. N.-H. Huynh, A. Karlsson, C. Pettersson, J. Chromatogr. A 1995, 705, 275-287.
16. V. Piette, M. Lämmerhofer, W. Lindner, J. Crommen, Chirality 1999, 11, 622-630.
17. V. Piette, M. Fillet, W. Lindner, J. Crommen, Biomed. Chromatogr. 2000, 14, 19-21.
18. Y. Carlsson, M. Hedeland, U. Bondesson, C. Petterson, J. Chromatogr. A 2001, 922, 303-311.
19. C. Pettersson, G. Schill, Chromatographia 1982, 16, 192-197.
20. G. Szepesi, M. Gazdag, R. Ivancsics, J. Chromatogr. 1982, 241, 153-167.
21. G. Szepesi, M. Gazdag, R. Ivancsics, J. Chromatogr. 1982, 244, 33-48.
22. H.K. Lim, M. Sardessei, J.W. Hubbard, K.K. Midha, J. Chromatogr. 1985, 328, 378-386.
23. R. Gotti, V. Andrisano, V. Cavrini, C. Bertucci, S. Furlanetto, J. Pharm. Biomed. Anal. 2000, 22, 423-431.
24. I. Bjorsndottir, S.H. Hansen, S. Terabe, J. Chromatogr. A 1996, 745, 37-44.
25. The European Pharmacopoeia, 4th Edition, Part 2.2.2, Council of Europe, Strasbourg, France 2002.
26. M. Chiari, M. Nesi, P.G. Rigetti, Capillary Electrophoresis in Analytical Biotechnology. CRC Press, Boca Raton 1996.
27. R. Ragonese, M. Macka, J. Hughes, P. Petocz, J. Pharm. Biomed. Anal. 2002, 27, 995-1007.