Oncogenic amino acid substitutions in the inhibitory rap-1a protein cause it to adopt a ras-p21-like conformation as computed using molecular dynamics

Journal of Biomolecular Structure and Dynamics

Volumn 13, Issue 6, 1996, Pages 925-933

  Chen, James M ^a   Brandt Rauf, Paul W ^b   Pincus, Matthew R ^c,d  

^a DUPONT COMPANY   (United States)

^b Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d SUNY DOWNSTATE MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; GUANOSINE TRIPHOSPHATE; MEMBRANE PROTEIN; ONCOPROTEIN; PROTEIN P21; RAS PROTEIN; TRANSCRIPTION FACTOR;

AMINO ACID SUBSTITUTION; ARTICLE; CELL TRANSFORMATION; MITOGENESIS; MOLECULAR DYNAMICS; ONCOGENE C JUN; ONCOGENE RAS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN LOCALIZATION;

AMINO ACID SEQUENCE; AMINO ACIDS; BINDING SITES; GTP-BINDING PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; ONCOGENE PROTEIN P21(RAS); PROTEIN CONFORMATION; RAP GTP-BINDING PROTEINS; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0029894427     PISSN: 07391102     EISSN: 15380254     Source Type: Journal    
DOI: 10.1080/07391102.1996.10508907     Document Type: Article

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