GABAergic synaptic communication in the GABAergic and non-GABAergic cells in the deep cerebellar nuclei

Neuroscience

Volumn 156, Issue 3, 2008, Pages 537-549

  Uusisaari, M ^a   Knopfel T ^a  

^a RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

Author keywords

cerebellar nuclei; GABAergic; synaptic transmission

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; TETRODOTOXIN;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL KINETICS; CELL SIZE; CELL TYPE; CEREBELLUM NUCLEUS; CONTROLLED STUDY; DENDRITE; GABAERGIC TRANSMISSION; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; SYNAPSE; SYNAPTIC TRANSMISSION;

ACTION POTENTIALS; ANALYSIS OF VARIANCE; ANIMALS; BIOMECHANICS; CEREBELLAR NUCLEI; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTRIC STIMULATION; GABA AGONISTS; GAMMA-AMINOBUTYRIC ACID; GLUTAMATE DECARBOXYLASE; GREEN FLUORESCENT PROTEINS; MICE; MICE, TRANSGENIC; NEURONS; PATCH-CLAMP TECHNIQUES; PYRIDINES; SODIUM CHANNEL BLOCKERS; SYNAPTIC TRANSMISSION; TEMPERATURE; TETRODOTOXIN;

EID: 53249095477     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2008.07.060     Document Type: Article

References (54)

1. Aizenman C.D., and Linden D.J. Rapid, synaptically driven increases in the intrinsic excitability of cerebellar deep nuclear neurons. Nat Neurosci 3 (2000) 109-111
2. Aizenman C.D., Manis P.B., and Linden D.J. Polarity of long-term synaptic gain change is related to postsynaptic spike firing at a cerebellar inhibitory synapse. Neuron 21 (1998) 827-835
3. Aizenman C.D., Huang E.J., and Linden D.J. Morphological correlates of intrinsic electrical excitability in neurons of the deep cerebellar nuclei. J Neurophysiol 89 (2003) 1738-1747
4. Akemann W., and Knöpfel T. Interaction of Kv3 potassium channels and resurgent sodium current influences the rate of spontaneous firing of Purkinje neurons. J Neurosci 26 (2006) 4602-4612
5. Alonso-Espinaco V., Elezgarai I., Diez-Garcia J., Puente N., Knopfel T., and Grandes P. Subcellular localization of the voltage-gated potassium channels Kv3.1b and Kv3.3 in the cerebellar dentate nucleus of Gad67-Gfp transgenic mice (2008) Neuroscience, available online 12 July 2008 doi:10.1016/j.neuroscience.2008.07.014.
6. Anchisi D., Scelfo B., and Tempia F. Postsynaptic currents in deep cerebellar nuclei. J Neurophysiol 85 (2001) 323-331
7. Bagnall M., Stevens R., and du Lac S. Transgenic mouse lines subdivide medial vestibular nucleus neurons into discrete, neurochemically distinct populations. J Neurosci 27 (2007) 2318-2330
8. Barberis A., Mozrzymas J.W., Ortinski P.I., and Vicini S. Desensitization and binding properties determine distinct alpha1beta2gamma2 and alpha3beta2gamma2 GABAA receptor-channel kinetic behavior. Eur J Neurosci 25 (2007) 2726-2740
9. Bäurle J., and Grüsser-Cornehls U. Differential number of glycine- and GABA-immunopositive neurons and terminals in the deep cerebellar nuclei of normal and Purkinje cell degeneration mutant mice. J Comp Neurol 382 (1997) 443-458
10. Browne S.H., Kang J., Akk G., Chiang L.W., Schulman H., Huguenard J.R., and Prince D.A. Kinetic and pharmacological properties of GABAA receptors in single thalamic neurons and GABAA subunit expression. J Neurophysiol 86 (2001) 2312-2322
11. Camp A., Callister R., and Brichta A. Inhibitory synaptic transmission differs in mouse type A and B medial vestibular nucleus neurons in vitro. J Neurophysiol 95 (2006) 3208-3218
12. Chan-Palay V. Cerebellar dentate nucleus: organization, cytology and transmitters (1977), Springer-Verlag, Berlin, Heidelberg, New York
13. Chen S., and Hillman D.E. Colocalization of neurotransmitters in the deep cerebellar nuclei. J Neurocytol 22 (1993) 81-91
14. Chen L., Yang C., and Mower G.D. Developmental changes in the expression of GABAA receptor subunits ([alpha]1, [alpha]2, [alpha]3) in the cat visual cortex and the effects of dark rearing. Mol Brain Res 88 (2001) 135-143
15. Czubayko U., Sultan F., Their P., and Schwarz C. Two types of neurons in the rat cerebellar nuclei as distinguished by membrane potentials and intracellular fillings. J Neurophysiol 85 (2001) 2017-2029
16. De Zeeuw C.I., and Berrebi A.S. Postsynaptic targets of Purkinje cell terminals in the cerebellar and vestibular nuclei of the rat. Eur J Neurosci 7 (1995) 2322-2333
17. De Zeeuw C.I., Van Alphen A.M., Hawkins R.K., and Ruigrok T.J. Climbing fibre collaterals contact neurons in the cerebellar nuclei that provide a GABAergic feedback to the inferior olive. Neuroscience 80 (1997) 981-986
18. Fritschy J., Benke D., Mertens S., Oertel W.H., Bachi T., and Mohler H. Five subtypes of type a {gamma}-aminobutyric acid receptors identified in neurons by double and triple immunofluorescence staining with subunit- specific antibodies. Proc Natl Acad Sci U S A 89 (1992) 6726-6730
19. Hardie J.B., and Pearce R.A. Active and passive membrane properties and intrinsic kinetics shape synaptic inhibition in hippocampal CA1 pyramidal neurons. J Neurosci 26 (2006) 8559-8569
20. Harney S.C., and Jones M.V. Pre- and postsynaptic properties of somatic and dendritic inhibition in dentate gyrus. Neuropharmacology 43 (2002) 584-594
21. Ito M. Cerebellar circuitry as a neuronal machine. Prog Neurobiol 78 (2006) 272-303
22. Jirenhed D., Bengtsson F., and Hesslow G. Acquisition, extinction, and reacquisition of a cerebellar cortical memory trace. J Neurosci 27 (2007) 2493-2502
23. Kawa K. Glycine receptors and glycinergic synaptic transmission in the deep cerebellar nuclei of the rat: a patch-clamp study. J Neurophysiol 90 (2003) 3490-3500
24. Laurie D.J., Seeburg P.H., and Wisden W. The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. II. Olfactory bulb and cerebellum. J Neurosci 12 (1992) 1063-1076
25. Lisberger S.G., and Sejnowski T.J. Motor learning in a recurrent network model based on the vestibulo-ocular reflex. Nature 360 (1992) 159-161
26. Lynch J.W. Molecular structure and function of the glycine receptor chloride channel. Physiol Rev 84 (2004) 1051-1095
27. Maccaferri G., Roberts J.D., Szucs P., Cottingham C.A., and Somogyi P. Cell surface domain specific postsynaptic currents evoked by identified GABAergic neurones in rat hippocampus in vitro. J Physiol 524 (2000) 91-116
28. Masuda N., and Amari S. A computational study of synaptic mechanisms of partial memory transfer in cerebellar vestibulo-ocular-reflex learning. J Comput Neurosci 24 (2008) 137-156
29. Mauk M.D. Roles of cerebellar cortex and nuclei in motor learning: contradictions or clues?. Neuron 18 (1997) 343-346
30. Meadows H.J., Kumar C.S., Pritchett D.B., Blackburn T.P., and Benham C.D. SB-205384: a GABA(A) receptor modulator with novel mechanism of action that shows subunit selectivity. Br J Pharmacol 123 (1998) 1253-1259
31. Molineux M.L., McRory J.E., McKay B.E., Hamid J., Mehaffey W.H., Rehak R., Snutch T.P., Zamponi G.W., and Turner R.W. Specific T-type calcium channel isoforms are associated with distinct burst phenotypes in deep cerebellar nuclear neurons. Proc Natl Acad Sci U S A 103 (2006) 5555-5560
32. Ohyama T., Nores W.L., Medina J.F., Riusech F.A., and Mauk M.D. Learning-induced plasticity in deep cerebellar nucleus. J Neurosci 26 (2006) 12656-12663
33. Ouardouz M., and Sastry B.R. Change in diazepam sensitivity of GABAA currents after LTP induction in neurons of deep cerebellar nuclei. Neurosci Lett 393 (2006) 147-149
34. Parsons R. Handbook of electrochemical constants (1960), Academic Press, New York
35. Paysan J., and Fritschy J.M. GABAA-receptor subtypes in developing brain. Actors or spectators?. Perspect Dev Neurobiol 5 (1998) 179-192
36. Pedroarena C.M., and Kamphausen S. Glycinergic synaptic currents in the deep cerebellar nuclei. Neuropharmacology 54 5 (2008) 784-795
37. Pedroarena C.M., and Schwarz C. Efficacy and short-term plasticity at GABAergic synapses between Purkinje and cerebellar nuclei neurons. J Neurophysiol 89 (2003) 704-715
38. Picton A.J., and Fisher J.L. Effect of the [alpha] subunit subtype on the macroscopic kinetic properties of recombinant GABAA receptors. Brain Res 1165 (2007) 40-49
39. Pritchett D.B., and Seeburg P.H. Gamma-aminobutyric acid A receptor alpha5-subunit creates novel type II benzodiazepine receptor pharmacology. J Neurochem 54 (1990) 1802-1804
40. Pugh J.R., and Raman I.M. GABAA receptor kinetics in the cerebellar nuclei: evidence for detection of transmitter from distant release sites. Biophys J 88 (2005) 1740-1754
41. Sceniak M., and Maciver M.B. Slow GABAA mediated synaptic transmission in rat visual cortex. BMC Neurosci 9 (2008) 8
42. Sekirnjak C., Vissel B., Bollinger J., Faulstich M., and du Lac S. Purkinje cell synapses target physiologically unique brainstem neurons. J Neurosci 23 (2003) 6392-6398
43. Spruston N., Jaffe D.B., Williams S.H., and Johnston D. Voltage- and space-clamp errors associated with the measurement of electrotonically remote synaptic events. J Neurophysiol 70 (1993) 781-802
44. Spruston N., Jaffe D.B., and Johnston D. Dendritic attenuation of synaptic potentials and currents: the role of passive membrane properties. Trends Neurosci 17 (1994) 161-166
45. Sultan F., König T., Möck M., and Thier P. Quantitative organization of neurotransmitters in the deep cerebellar nuclei of the Lurcher mutant. J Comp Neurol 452 (2002) 311-323
46. Tamamaki N., Yanagawa Y., Tomioka R., Miyazaki J., Obata K., and Kaneko T. Green fluorescent protein expression and colocalization with calretinin, parvalbumin, and somatostatin in the GAD67-GFP knock-in mouse. J Comp Neurol 467 (2003) 60-79
47. Telgkamp P., and Raman I.M. Depression of inhibitory synaptic transmission between Purkinje cells and neurons of the cerebellar nuclei. J Neurosci 22 (2002) 8447-8457
48. Telgkamp P., Padgett D.E., Ledoux V.A., Woolley C.S., and Raman I.M. Maintenance of high-frequency transmission at Purkinje to cerebellar nuclear synapses by spillover from boutons with multiple release sites. Neuron 41 (2004) 113-126
49. Teune T.M., van der Burg J., and Ruigrok T.J. Cerebellar projections to the red nucleus and inferior olive originate from separate populations of neurons in the rat: a non-fluorescent double labeling study. Brain Res 673 (1995) 313-319
50. Uusisaari M., Obata K., and Knöpfel T. Morphological and electrophysiological properties of GABAergic and non-GABAergic cells in the deep cerebellar nuclei. J Neurophysiol 97 (2007) 901-911
51. Wada N., Kishimoto Y., Watanabe D., Kano M., Hirano T., Funabiki K., and Nakanishi S. Conditioned eyeblink learning is formed and stored without cerebellar granule cell transmission. Proc Natl Acad Sci U S A 104 (2007) 16690-16695
52. Wassef M., Simons J., Tappaz M.L., and Sotelo C. Non-Purkinje cell GABAergic innervation of the deep cerebellar nuclei: A quantitative immunocytochemical study in C57BL and in Purkinje cell degeneration mutant mice. Brain Res 399 (1986) 125-135
53. Wei W., Zhang N., Peng Z., Houser C.R., and Mody I. Perisynaptic localization of {delta} subunit-containing GABAA receptors and their activation by GABA spillover in the mouse dentate gyrus. J Neurosci 23 (2003) 10650-10661
54. - currents in rat thalamic reticular and relay neurons. J Neurophysiol 78 (1997) 2280-2286