Computational structure-activity relationship analysis of non-peptide inducers of macrophage tumor necrosis factor-α production

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 20, 2008, Pages 9302-9312

  Khlebnikov, Andrei I ^a   Schepetkin, Igor A ^b   Kirpotina, Liliya N ^b   Quinn, Mark T ^b  

^a ALTAI STATE TECHNICAL UNIVERSITY   (Russian Federation)

^b MONTANA STATE UNIVERSITY   (United States)

Author keywords

Atom pairs; Macrophage; Molecular descriptors; Structure activity relationship analysis; Tumor necrosis factor

Indexed keywords

CARBOXYLIC ACID DERIVATIVE; HYDRAZIDE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA;

ACCURACY; ALGORITHM; ANIMAL CELL; ARTICLE; CYTOKINE PRODUCTION; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG STRUCTURE; MACROPHAGE; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; CELL LINE; CELL PROLIFERATION; COMBINATORIAL CHEMISTRY TECHNIQUES; COMPUTER SIMULATION; HYDRAZINES; MACROPHAGES; MICE; MOLECULAR STRUCTURE; PEPTIDES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR NECROSIS FACTOR-ALPHA;

EID: 53249095402     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.08.078     Document Type: Article

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