Disulfide bond within μ-calpain active site inhibits activity and autolysis

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1784, Issue 9, 2008, Pages 1215-1221

  Lametsch, René ^a   Lonergan, Steven ^b   Huff Lonergan, Elisabeth ^b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b IOWA STATE UNIVERSITY   (United States)

Author keywords

Cysteine modification; Disulfide bond; LC MS; Oxidation; calpain

Indexed keywords

AMINO ACID; CALPAIN 1; CYSTEINE; HYDROGEN PEROXIDE; CALPAIN; DISULFIDE; MERCAPTOETHANOL; MU-CALPAIN;

ARTICLE; AUTOLYSIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISULFIDE BOND; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; OXIDATION; PRIORITY JOURNAL; PROTEIN MODIFICATION; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVE SITE; IN VITRO STUDY; METABOLISM; OXIDATION REDUCTION REACTION; SKELETAL MUSCLE; SWINE; TANDEM MASS SPECTROMETRY;

ANIMALS; AUTOLYSIS; CALPAIN; CATALYTIC DOMAIN; CHROMATOGRAPHY, LIQUID; DISULFIDES; HYDROGEN PEROXIDE; MERCAPTOETHANOL; MODELS, MOLECULAR; MUSCLE, SKELETAL; OXIDATION-REDUCTION; SWINE; TANDEM MASS SPECTROMETRY;

EID: 53149136625     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2008.04.018     Document Type: Article

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