Immunohistochemical evaluation of insulin-like growth factor I receptor status in cervical cancer specimens

Acta Medica Okayama

Volumn 62, Issue 4, 2008, Pages

  Kuramoto, Hiroyuki ^a   Hongo, Atsushi ^a   Liu, Yi Xuan ^a   Ojima, Yojiro ^a   Nakamura, Keiichiro ^a   Seki, Noriko ^a   Kodama, Junichi ^a   Hiramatsu, Yuji ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

Cervical cancer; Human papillomavirus; Insulin like growth factor I receptor; Tyrosil phosphorylation

Indexed keywords

HUMAN PAPILLOMAVIRUS;

ONCOPROTEIN; SOMATOMEDIN C RECEPTOR;

ARTICLE; EVALUATION; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; METABOLISM; PATHOLOGY; UTERINE CERVIX CARCINOMA IN SITU; UTERINE CERVIX TUMOR; VIRUS INFECTION;

CERVICAL INTRAEPITHELIAL NEOPLASIA; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; ONCOGENE PROTEINS, VIRAL; PAPILLOMAVIRUS INFECTIONS; RECEPTOR, IGF TYPE 1; UTERINE CERVICAL NEOPLASMS;

EID: 53149132023     PISSN: 0386300X     EISSN: 0386300X     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. zur Hausen H and Schneider A: The role of papillomaviruses in human anogenital cancer. Papovaviridae (1987) 2: 245-263.
2. Howley PM: Role of human papillomaviruses in human cancer. Cancer Res (1991) 51: 5019s-5022s.
3. Walboomers JMM, Jacobs MV, Manos MM, Bosch FX, Kummer JA, Shah KV, Snijders PJF, Peto J, Meijer CJLM and Muñoz N: Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J Pathol (1999) 189: 12-19.
4. Scheffner M, Werness BA, Huibregtse JM, Levine AJ and Howley PM: The E6 oncoprotein encoded by human papillomavirus type-16 and type-18 promotes the degradation of p53. Cell (1990) 63: 1129-1136.
5. Huibregtse JM, Scheffner M and Howley PM: A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18. EMBO J (1991)10: 4129-4135.
6. Scheffner M, Huibregtse JM, Vierstra RD and Howley PM: The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell (1993) 75: 495-505.
7. Chellappan S, Kraus VB, Kroger B, Münger K, Howley PM, Phelps WC and Nevins JR: Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product. Proc Natl Acad Sci USA (1992) 89: 4549-4553.
8. Boyer SN, Wazer DE and Band V: E7 protein of human papilloma virus-16 induces degradation of retinoblastoma protein through the ubiquitin-proteasome pathway. Cancer Res (1996) 56: 4620-4624.
9. Jones DL, Thompson DA and Münger K: Destabilization of the RB tumor suppressor protein and stabilization of p53 contribute to HPV 16 E7-induced apoptosis. Virology (1997) 239: 97-107.
10. Baserga R, Hongo A, Rubini M, Prisco M and Valentinis B: The IGF-I receptor in cell growth, transformation and apoptosis. Biochim Biophys Acta (1997)1332: F105-126.
11. Rubini M, Hongo A, D'Ambrosio C and Baserga R: The IGF-I receptor in mitogenesis and transformation of mouse embryo cells: role of receptor number. Exp Cell Res (1997) 230: 284-292.
12. Nielsen TO, Andrews HN, Cheang M, Kucab JE, Hsu FD, Ragaz J, Gilks CB, Makretsov N, Bajdik CD, Brookes C, Neckers LM, Evdokimova V, Huntsman DG and Dunn SE: Expression of the insulin-like growth factor I receptor and urokinase plasminogen activator in breast cancer is associated with poor survival: potential for intervention with 17-allylamino geldanamycin. Cancer Res (2004) 64: 286-291.
13. Furukawa M, Raffeld M, Mateo C, Sakamoto A, Moody TW, Ito T, Venzon DJ, Serrano J and Jensen RT: Increased expression of insulin-like growth factor I and/or its receptor in gastrinomas is associated with low curability, increased growth, and development of metastasis. Clin Cancer Res (2005) 11: 3233-3242.
14. Prisco M, Hongo A, Rizzo MG, Sacchi A and Baserga R: The insulin-like growth factor I receptor as a physiologically relevant target of p53 in apoptosis caused by interleukin-3 withdrawal. Mol Cell Biol (1997)17: 1084-1092.
15. Sell C, Dumenil G, Deveaud C, Miura M, Coppola D, DeAngelis T, Rubin R, Efstratiadis A and Baserga R: Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts. Mol Cell Biol (1994) 14: 3604-3612.
16. Rubini M, D'Ambrosio C, Carturan S, Yumet G, Catalano E, Shan S, Huang Z, Criscuolo M, Pifferi M and Baserga R: Characterization of an antibody that can detect an activated IGF-I receptor in human cancers. Exp Cell Res (1999) 251: 22-32.
17. Durst M, Glitz D, Schneider A and zur Hausen H: Human papillomavirus type 16 (HPV 16) gene expression and DNA replication in cervical neoplasia: analysis by in situ hybridization. Virology (1992)189: 132-140.
18. Staler MH, Rhodes CR, Whitbeck A, Wolinsky SM, Chow LT and Broker TR: Human papillomavirus type 16 and 18 gene expression in cervical neoplasia. Hum Pathol (1992) 23: 117-128.
19. Snijders PJF, Steenbergen RDM, Heideman DAM and Meijer CJLM: HPV-mediated cervical carcinogenesis: concepts and clinical implications. J Pathol (2006) 208: 152-164.
20. Klaes R, Woerner SM, Ridder R, Wentzensen N, Duerst M, Schneider A, Lotz B, Melsheimer P and von Knebel Doeberitz M: Detection of high-risk cervical intraepithelial neoplasia and cervical cancer by amplification of transcripts derived from integrated papillomavirus oncogenes. Cancer Res (1999) 59: 6132-6136.
21. zur Hausen H: Pappilomaviruses and cancer: from basic studies to clinical application. Nat Rev Cancer (2002) 2: 342-350.
22. Klaes R, Friedrich T, Spitkovsky D, Ridder R, Rudy W, Petry U, Dallenbach-Hellweg G, Schmidt D and von Knebel Doeberitz M: Overexpression of p16(INK4A) as a specific marker for dysplastic and neoplastic epithelial cells of the cervix uteri. Int J Cancer (2001) 92: 276-84.
23. Dray M, Russell P, Dalrymple C, Wallman N, Angus G, Leong A, Carter J and Cheerala B: p16(INK4a) as a complementary marker of high-grade intraepithelial lesions of the uterine cervix. I: Experience with squamous lesions in 189 consecutive cervical biopsies. Pathology (2005) 37: 112-124.